• Journal of Pharmaceutical Investigation
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• v.24 no.3
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• pp.109-113
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• 1994

Effects of various formulation factors using $L_8$ orthogonal arrays with the stability of doxorubicin hydrochloride injections(DHls) were investigated. The degradation of DHI may be occured by pH, temperature, light and metal ions. It is known that DHI should be stored on refrigerated condition of $4{\sim}8^{\circ}C$ because of its unstability on the room temperature. The employed factors were sodium chloride as isotonic solution, sodium bisulfite or sodium pyrosulfite as an antioxidant, disodium edetate as a chelating agent, methyl parahydroxybenzoate as a dissolution time shortening agent, and hydrochloric acid or citric acid as a pH adjusting agent at $22^{\circ}C$. From the results of $L_8$ orthogonal arrays, an optimal formula, including sodium chloride, disodium edetate, sodium bisulfite and hydrochloric acid, was obtained and the shelf-life of the formula was determined as 560 days approximately.

• Journal of Industrial Technology
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• v.31 no.B
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• pp.59-65
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• 2011

In this study, LCD Cell process has been analyzed through ARENA simulation. The major concern is to find the condition maximizing production rate (or quantity per hour). For the analysis, we have selected 4 factors and performed simulation experiments through $L_8(2^7)$ orthogonal arrays. Our results indicate that the production may be maximized with well selected conditions proposed in this study. The results obtained from this study may provide a good base for practical applications.

• Journal of Ocean Engineering and Technology
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• v.20 no.4 s.71
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• pp.37-42
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• 2006

This paper is concerned with experimental investigation of steering performance of a tracked vehicle on extremely soft soil. A tracked vehicle model with principal dimensions of 0.9 m(L)x0.75 m(B)x0.4 m(H) and weight of 167 kg was constructed with a pair of driving chain links, driven by two AC-servo motors. The tracks were configured with detachable grousers with variable span. A deep seabed was simulated by means of a bentonite-water mixture in a soil bin of 6.0 m(L)x3.7 m(B)x0.7 m(H). The turning radii of vehicle and driving torques of motors were measured with respect to experiment variables: steering ratio, driving speed, grouser chevron angle, grouser span, and grouser height. L8 orthogonal table is adopted for DOE (Design of experiment). The effects of experiment variables on steering performance are evaluated.

• Ocean and Polar Research
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• v.26 no.2
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• pp.333-339
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• 2004

This paper is concerned with an experimental investigation about tractive performance of a tracked vehicle on extremely soft soil. A tracked vehicle model with principal dimensions of $0.9\;m(L)\;{\times}\;0.75\;m(B)\;{\times}\;0.4\;m(H)$ and the weight of 167 kg was constructed with a pair of driving chain links driven by two AC-servo motors. The tracks are configured with detachable grousers with variable span. Deep seabed was simulated by means of bentonite-water mixture in a soil bin of $6.0\;m(L)\;{\times}\;3.7\;m(B)\;{\times}\;0.7\;m(H)$. Slip of vehicle and driving torque of motor were measured with respect to experimental variables; grouser span, grouser chevron angle, driving speed, drawbar-pull weight, position of center-of-gravity and weight. $L_8$ orthogonal array is adopted for DOE (Design Of Experiment). The effects of experiment variables on traction performance are evaluated.

• Solar Energy
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• v.20 no.1
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• pp.91-96
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• 2000

This study was performed to find out how much experimental factors influence on regeneration performance in a solar air conditioning system. The experimental apparatus was set up in a climate-controlled chamber where temperature and humidity could be kept constant. In order. to investigate factors' influence on the regeneration performance of the solar air conditioning system, the model experiment was done using the 600mm $\times$ 600mm black painted aluminum regenerator. The design and analysis of experiment were done by the design of experiments, especially the table of orthogonal arrays. In order to find out how much experimental factors influence on regeneration performance, the table of orthogonal arrays $L_8(2^7)$ was used. According to the results, it was found that the most influential factor to affect regeneration performance was the concentration of LiCl solution. The next influential factors were a solar radiation, an air velocity, and the temperature of LiCl solution in order.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.39 no.4
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• pp.90-96
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• 2016

Incremental sheet forming (ISF) is a highly versatile and flexible process for rapid manufacturing of complex sheet metal parts. Compared to conventional sheet forming processes, ISF is of a clear advantage in manufacturing small batch or customized parts. ISF needs die-less machine alone, while conventional sheet forming requires highly expensive facilities like dies, molds, and presses. This equipment takes long time to get preparation for manufacturing. However, ISF does not need the full facilities nor much cost and time. Because of the facts, ISF is continuously being used for small batch or prototyping manufacturing in current industries. However, spring-back induced in the process of incremental forming becomes a critical drawback on precision manufacturing. Since sheet metal, being a raw material for ISF, has property to resilience, spring-back would come in the case. It is the research objective to investigate how geometrical shaping parameters make effect on shape dimensional errors. In order to analyze the spring-back occurred in the process, this study experimented on Al 1015 material in the ISF. The statistical tool employed experimental design with factors. The table of orthogonal arrays of $L_8(2^7)$ are used to design the experiments and ANOVA method are employed to statistically analyze the collected data. The results of the analysis from this study shows that the type of shape and the slope of bottom are the significant, whereas the shape size, the shape height, and the side angle are not significant factors on dimensional errors. More error incurred on the pyramid than on the circular type in the experiments. The sloped bottom showed higher errors than the flat one.

• Journal of the Semiconductor & Display Technology
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• v.8 no.4
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• pp.1-5
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• 2009

This investigation is applied Taguchi method and the analysis of variance(ANOVA) to the reactive ion etching(RIE) characteristics of $SiO_2$ film coated on a wafer with Experimental Analysis and Optimization of $CF_4/O_2$ Plasma Etching Process mixture. Plans of experiments via nine experimental runs are based on the orthogonal arrays. A $L_9$ orthogonal array was selected with factors and three levels. The three factors included etching time, RF power, gas mixture ratio. The etching rate of the film were measured as a function of those factors. In this study, the etching thickness mean and uniformity of thickness of the RIE are adopted as the quality targets of the RIE etching process. The partial factorial design of the Taguchi method provides an economical and systematic method for determining the applicable process parameters. The RIE are found to be the most significant factors in both the thickness mean and the uniformity of thickness for a RIE etching process.

• Journal of the Korean Ceramic Society
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• v.33 no.2
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• pp.155-162
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• 1996

A Taguchi methodology study of the plasma spraying thermal barrier coating (TBC) layer is presented. The experiment parameters were designed by a L8-style orthogonal arrays approach. A Taguchi analysis was conduc-ted through the results of the coating properties which were affected by plasma spraying parameters. Zirconia (partially stbilized with ytrria: PSZ) was sprayed on TiAl intermetallic compound substrates, The coating layer was characterized by thickness microstructure and porosity using SEM and Image analyzer. The coating quali-ties are discussed with respect to thermal barrier effect thermal cycling test6 and adhesion strength test. An optimum condition of plasma spraying process which are derived from the Taguchi analysis could be found for high quality TBC.

• Solar Energy
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• v.19 no.4
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• pp.55-62
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• 1999

This study was performed to find out the influence of experimental factors on dehumidification performance and furthermore to suggest an optimal combination of factors of a total heat exchanger in a solar air conditioning system. The experimental apparatus was set up in a climate-controlled chamber where the temperature and humidity was maintained constant. In order to find out the contribution ratio of factors on dehumidification performance, the table of orthogonal arrays $L_8(2^7)$ was used. According to the results, the most influential factor on dehumidification performance was the concentration of LiCl(Lithium Chloride) solution. The next influential factors were the temperature of LiCl solution and the air flow rate. The packed layer height, packed material, and flow rate of LiCl solution had no influence on the dehumidification performance under these experimental conditions. Through the three level experiments of $L_{27}(3^{13})$, it was found that the optimal combination was $A_2B_0G_2$(concentration of solution 30 wt%, temperature of solution $15^{\circ}C$, air flow rate $253m^3/h$).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.8
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• pp.4729-4735
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• 2014

To protect the environment, the regulation of emissions from off-road engines which are relatively neglected, is being reinforced. This paper deals with the robust design of off-road diesel engines considering the emission characteristics. Measurements of the NOx and PM levels based on the DOE were carried out. The injector hole number, injection timing and EGR rate were selected as the control factors. The orthogonal arrays table $L_9(3^3)$ was made from 2 or 3 levels for each factor and measurements of emissions were accomplished based on the table. The small-the-better SN ratio according to the Taguchi method was evaluated. The ANOVA (analysis of variance) for the SN ratio was conducted. The injection timing on the NOx emissions and the EGR rate on the PM have the largest effect on the low-load operation condition. The confidence levels of the control factors were more than 90%.