• Title/Summary/Keyword: $L_{eq}$

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Effect of thyroparathyroidectomy on urinary excretion of sodium, potassium, calcium and phosphate in the rabbits (갑상선 부갑상선 적출이 뇨중 Na, K, Ca 및 $PO_4$ 배설에 미치는 영향)

  • Choi, Duck-Kyung
    • The Korean Journal of Physiology
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    • v.16 no.1
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    • pp.69-76
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    • 1982
  • The effect of parathyroid hormone on calcium and phosphate metabolism have been widely investigated, however less attention has been paid to the effect on urinary excretion. This study was performed for the purpose determining urinary excretion of Na, K, Ca, and $Po_4$, of 18 thyroparathyroidectomized (TPTX) rabbits, which were TPTX previously 7 to 10 days compared with the same normal ones. After TPTX 0.2 mg/day of synthyroid was donated to the rabbits. The concentration of electrolytes in the serum and urine was determined by the following method; Na and K were determined by means of flame photometry, Ca was by EDTA titration $method^{19)}$, and $Po_4$ by Fiske and Subba-Raw $method^{20)}$. The results as follows. The concentrations of electrolytes in the serum were 1) In the normal control rabbits (N = 25) (data, $Mean{\pm}S.E.$) $Na\;131.72{\pm}1.33\;mEq/L$, $K\;3.59{\pm}0.28\;mEq/L$, $Ca\;12.58{\pm}0.29\;mg%$, $Po_4\;4.50{\pm}\;0.45mg%$. 2) In the TPTX rabbits(N= 18) $Na\;140.6l{\pm}2.56\;mEq/L$, $K\;3.38{\pm}0.36\;mEq/L$, $Ca\;l2.18{\pm}0.45\;mg%$, $Po_4\;3.92{\pm}\;0.35\;mg%$. There was no significant change between the normal and TPTX rabbits. The concentration of elelctrolytes in the urine were variously changed. 3) In the normal rabbits. $Na\;8.40{\pm}1.09\;mEq/L$, $K\;81.59{\pm}10.19\;mEq/L$, $Ca\;16.02{\pm}3.12\;mg%$, $Po_4\;13.16{\pm}2.89mg%$. 4) In the TPTX rabbits, $Na\;14.57{\pm}3.39\;mEq/L$ slight ncreased, $K\;116.06{\pm}12.77\;mEq/L$ significant increased (P<0.05), $Ca\;18.90{\pm}5.44\;mg%$ no significant increased, $Po_4\;43.38{\pm}8.67\;mg%$ significant increased (p<0.01). The effect of TPTX was assumed that it affected upon increasing tubular secretion of $K^+$ and inhibition of the tubular reabsorption of $Po_4$.

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A Study on the Ingredients in the Sap of Acer mono MAX. and Betula costata T. in Mt. Jiri Area -On the Components of Mineral and Sugar- (지리산지역 고로쇠나무 및 거제수(거자수) 나무의 수액성분에 관하여 -Mineral과 Sugar성분에 관하여-)

  • 서화중;김충모;정두례
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.20 no.5
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    • pp.479-482
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    • 1991
  • The medical use of Acer mono MAX. and Betula costata T. sap has had the long history in Korea. So the mineral and sugar contents of these sap gathered in Mt. Jiri area at spring were analyzed to investigate the scientific base of folk remedies by using ion liquid chromatography and high performance liquid chromatography. The values of chlorine and sulfate in Acer mono MAX. were 11.5 mg/l and 176.7 mg/l, and in Betula costata T. 26.5 mg/l and 162.4 mg/l, respectively. The values of potassium, sodium, calcium and magnesium in Acer mono MAX. were 67.9 mg/l, 5.6 mg/l, 73.8 mg/l and 4.5 mg/l, and in Betula costata T. were 152.1 mg/l, 9.7 mg/l, 39.2 mg/l and 5.7 mg/l, respectively. The values of copper, zinc and manganese in Acer mono MAX. were 0.057 mg/l, 0.483 mg/l and 5.071 mg/l, and copper, zinc, mangances and iron in Betula costata T. were 0.038 mg/l, 1.584 mg/l, 4.354 mg/l and 2.511 mg/l, respectively. The values of sucrose in Acer mono MAX. were 27.29 mg/l, glucose and fructose in Betula costata T. were 0.97 g/l and 3.05 g/l, respectively.

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A Clinical Study of Changes in Serum Electrolyte Concentration During and After Extracorporeal Circulation with Heart-Lung Machine (심폐기 체외순환에 의한 혈청 전해질 변동에 관한 연구)

  • 김근호
    • Journal of Chest Surgery
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    • v.11 no.4
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    • pp.404-415
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    • 1978
  • The present study was carried out to develop the better measures for safety of open heart surgery under extracorporeal circulation (ECC) with Heart-Lung-Machine by preventing changes in the concentrations of serum electrolytes during and after ECC. For this purpose, the cocentrations of serum electrolytes were measured before, during, and after ECC in 21 patients with congenital and acquired heart diseases who received open heart surger, - under ECC using Heart-Lung-Machine. Also considered was the development of safety measured by which changes in serum electrolyte concentrations were prevented during and after open heart surgery under ECC. The mean values for serum sodium levels were observed to be ; $13.14{\pm}0.47$mEq./L. for the samples obtained before ECC. $139.59{\pm}0.68$mEq./L. for the samples obtained 10 minutes after ECC and $138.0{\pm}0.68$mEq./L. for the samples obt"ined 24 hours after ECC. These results indicate that serum sodium concentrations were \\'ithin normal range during and until 24 hours after ECC. 2) The concentrations of serum chloride were found to be $105.38{\pm}0.70$105.38$\pm$0. 70 mEq./L. for the samples collected before ECC, $105.07{\pm}1.01$mEq./L. for the Simples collected 24 minutes aiter ECC and $101.95{\pm}1.09$mEq./L. for the samples collectect 24 hours afte ECC. As was tile case with serum sodium levels, no significant changes were observed in serum chloride levels during and 24 hours after ECC. 3)With proper provisions of potassium chloride solution during ECC, the concentrations of serum potassium were found to be $4.22{\pm}0.06$mEq./L. for the samples removed before EeC, $4.06{\pm}0.14$mEq./L. for the samples removed 10 minutes after ECC and $4.39{\pm}0.07$ mEq./L. for the samples removed 24 hours after ECC. 4)The concentrations of serum calcium were also maintained within normal during and after ECC; $9.15{\pm}0.14$mg/dl for the serum collected before ECC, $8.36{\pm}0.21$mg/dI for the serum collected 10 minutes after ECC and $8.47{\pm}0.14$mg/dl 21 hours after ECC. The maintenance of serum calcium level within normal throughout ECC was achieved by parenteral administrations of calcium gluconate as frequent as required. 5) As were the cases with serum potassium and calcium, the concentrations of plasma bicarbonate was regulated within normal range during and after ECC, only when sodium bicarbonate solution was admini"tered parenterally as it was required; $23.7{\pm}0.50$mEq./L. for the serum collected before ECC. $22.33{\pm}1.09$mEq.lL. for the serum collected 10 minutes after ECC and $25.3{\pm}0.96$mEq./L. for the serum collected 24 hours after ECC. The above results indicate tha t during and after ECC serum sodium and chloride levels remined unchanged without any provision of normal saline, while serum potassium, calcium, and bicarbonate concentrations were kept within normal limits only when these ealectrolytes were administered through parenteral routes. With these results it can be concluded that serum potassium, calcium, and bicarbonate levels should be determined as often as possible during and after ECC and that in order to maintain serum electrolyte levels within normal these electrolytes in the forms of potassium chloride, calcium gluconate, and sodium bicarbonate shou'd be given parenterally as they were found to be required.

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The Decline of Health-Related Quality of Life Associated with Some Diseases in Korean Adults (우리나라 성인에서 일부 질환과 연관된 건강관련 삶의 질 감소)

  • Kil, Seol-Ryoung;Lee, Sang-Il;Yun, Sung-Cheol;An, Hyung-Mi;Jo, Min-Woo
    • Journal of Preventive Medicine and Public Health
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    • v.41 no.6
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    • pp.434-441
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    • 2008
  • Objectives: This study was conducted to measure the decline in the health-related quality of life (HRQoL) associated with some diseases in South Korean adults. Methods: The EQ-5D health states in the 2005 National Health and Nutrition Examination Survey (NHNES) and the Korean EQ-5D valuation set were used to obtain the EQ-5D indexes of the study subjects. Each disease group was defined when the subjects reported to the NHNES that they were diagnosed with the corresponding disease during the previous 1 year by physicians. Since the distributions of the EQ-5D indexes in each subgroup were negatively skewed, median regression analysis was used to estimate the effects of specific diseases on the HRQoL. Median regression analysis produced estimates that approximated the median of the EQ-5D indexes and there are more robust for analyzing data with many outliers. Results: A total of 16,692 subjects (6,667 patients and 10,025 people without any disease) were included in the analysis. As a result of the median regression analysis, stroke had the strongest impact on the HRQoL for both males and females, followed by osteoporosis, osteoarthritis, rheumatic arthritis, and herniation of an intervertebral disc. While asthma had a significant impact on the HRQoL only in men, cataract, temporo-mandibular dysfunction, and peptic ulcer significantly affected the HRQoL only in women. Conclusions: Stroke and musculoskeletal diseases were associated with the largest losses of the HRQoL in Korean adults.

A Study on the Establishment of the Environmental Noise Criteria for Aircraft (항공기 소음 환경 기준 설정을 위한 연구)

  • Kim, Sun-Woo;Jang, Gil-Soo;Lee, Soo-Gab;Song, Min-Jeong;Chang, Se-Myong;Jeon, Ji-Hyun;Ahn, Byung-Og
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.12 no.6
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    • pp.420-430
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    • 2002
  • Rating scales for environmental noise are varied in their calculation procedure. Among them WECPNL (weighted equivalent continuous perceived noise level) is the rating scale for aircraft noise currently being used in domestic and applied only for aircraft noise. However $L_{dn}$ calculated from $L_{eq}$ $L_{eq}$ is used as a rating scale for not only aircraft noise but also environmental noise. Besides, it is easy to calculate and internationally preferred. It is, therefore, not adequate for the evaluation of residents' exposure. Moreover it is very difficult to measure the aircraft noise by WECPNL due to the complicated calculating procedures if automatic measuring system is not used. Accordingly. this study aims to propose alternative evaluation procedure for the aircraft noise. To achieve this purpose, the data measured by automatic measuring system were gathered and calculated with three evaluation procedures : WECPNL $L_{eq}$ and $L_{dn}$, and the results calculated from different methods were compared and analyzed.

Physiological Responses of Olive Flounder (Paralichthys olivaceus) by Capacity Density Difference during Salinity Change from Seawater to Freshwater (사육수의 담수화시 수용밀도에 따른 넙치(Paralichthys olivaceus)의 생리적 반응 비교)

  • Hur Jun Wook;Lee Bok Kyu;Min Byung Hwa;Park In-Seok;Choi Cheol Young;Lee Jeong Yeol;Chang Young Jin
    • Korean Journal of Environmental Biology
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    • v.22 no.3
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    • pp.419-425
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    • 2004
  • Two different groups (30 and 60 inds.) of olive flounder (Paralichthys olivaceus) were abruptly (within 30 min) exposed to hypo-salinities from seawater (SW, 35$\textperthousand$) to freshwater (FW, 0$\textperthousand$) (30FW and 60FW) and to 35$\textperthousand$ (30SW and 60SW) in a flow through seawater culture systems. Analysis of plasma samples showed the following significant increase at 0$\textperthousand$: cortisol from $2.8\;ng\;mL^{-1}$ to $66.9\;ng\;mL^{-1}$ (30FW) and from $2.7\;ng\;mL^{-1}$ to $314.1\;ng\;mL^{-1}$ (60FW) after 24 hours of exposure; glucose from $15.8\;mg\;dL^{-1}$ to $257.7\;mg\;dL^{-1}$ after 3 hours exposure and to $164.0\;mg\;dL^{-1}$ after 24 hours in 60FW. Plasma $Na^+$ concentration of 30FW and 60FW were decreased until 24 hours after expose. However that in 30SW and 60SW showed no significant differences. Plasma $Cl^-$ concentration of 60FW was decreased from $59.0\;mEq\;L^{-1}$ to $43.5\;mEq\;L^{-1}$ and to $30.0\;mEq\;L^{-1}$ after 3 and 24 hours of exposure, respectively. At all experimental groups, survival were 100% until 24 hours.

Systemic effects of multidose hypothermic potassium cardioplegia: an experimental study in six dogs (냉혈 K 심정지액의 반복사용시 전신적인 영향동물실험 6)

  • 기노석
    • Journal of Chest Surgery
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    • v.17 no.4
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    • pp.587-592
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    • 1984
  • Potassium cardioplegia for myocardial preservation is being used extensively in open heart surgery. This study was designed to investigate the change in serum and urine potassium before, during, after the administration of cold blood potassium cardioplegic solution containing 28-30 mEq/L [28.6\ulcorner.56 mEq/L] of potassium chloride in 6 dogs. Total potassium dose used in the study was 14.9\ulcorner.89 mEq/L [1.2 mEq/Kg]. Mean potassium level in serum was within normal limits. Urinary excretion of potassium decreased during bypass but increased after bypass and eventually exceeded the amount of potassium infused as cold blood potassium cardioplegic solution. While cold blood potassium cardioplegia is a safe and efficient method of myocardial protection, postoperative potassium level must be observed carefully in order to detect obligatory potassium excretion following open heart surgery.

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The Effect of Korean Elderly's Prosthetic Status on Health Related Quality by Using EuroQol-5 Dimension (한국 노인의 보철상태에 따른 건강관련 삶의 질)

  • Park, Jeong-Hye;Lee, Min-Kyung;Lee, Jung-Hwa;Jin, Hye-Jung
    • Journal of dental hygiene science
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    • v.14 no.3
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    • pp.417-423
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    • 2014
  • The aim of this study was to evaluate the relationship between prosthetic status and health related quality of elderly by using EuroQol-5 dimension (EQ-5D) which is a standardized instrument used as a measure of health outcome. Data from 1,179 elderly subjects (over 65 years old) from the fifth Korea National Health and Nutrition Examination Survey were used in our analysis. Oral examination were conducted to obtain wearing prosthetic and needed prosthetic. EQ-5D is a widely used health condition measuring instrument. It consists of the five dimensions: Mobility, Self-care, Usual activities, Pain/discomfort and Anxiety/depression. EQ-5D index is a score calculated out of a weighting system. In this study, the mean score of the EQ-5D index among the elderly was 0.86. For EQ-5D index gender, female showed statistically significantly lower quality of life than male. The related factors EQ-5D index, when the lower demand for fixed prosthodontics and full denture. Wearers in partial and complete denture than non-wearers showed higher EQ-5D index. In order to improve EQ-5D index among the elderly who demand prosthetic status, which has lost its function through providing proper dental prostheses.

A compare study on the Evaluation Method of Aircraft Noise (항공기 소음의 평가 척도에 대한 비교 연구)

  • 전지현;안병옥;송민정;장길수;김선우
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2001.11b
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    • pp.703-706
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    • 2001
  • Currently domestic criteria for the aircraft noise is being adapted WECPNL(weighted equivalent continuous perceived noise level), while internationally preferred method is which is originated from $L_{eq}$ and can evaluate even environmental noise. WECPNL used in domestic as a evaluation method is only for the aircraft noise. It is, therefore, not adequate for the evaluation of residents' injury, moreover, it is very difficult to measure the aircraft noise with WECPNL due to the complicated calculating procedures as long as automatic measuring system is not used. Accordingly, this study aims to propose alternative evaluation method for the aircraft noise. To achieve this purpose, the data measured by automatic measuring system were gathered and calculated with three evaluation methods: WECPNL, $L_{eq}$ and $L_{dn}$ and the results calculated from different methods were compared and analyzed.

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Evaluation of Health-Related Quality of Life among Patients with Cervical Cancer in Indonesia

  • Endarti, Dwi;Riewpaiboon, Arthorn;Thavorncharoensap, Montarat;Praditsitthikorn, Naiyana;Hutubessy, Raymond;Kristina, Susi Ari
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.8
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    • pp.3345-3350
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    • 2015
  • Background: Evaluation of health-related quality of life (HRQOL) in cervical cancer patients is important in order to design the interventions for improving patient outcomes. Reports of HRQOL among cervical cancer patients in Indonesia are limited. Moreover, measurement using EQ-5D-3L is to our best knowledge has hitherto not been performed. This study aimed to examine the HRQOL of cervical cancer patients in Indonesia using EQ-5D-3L. Materials and Methods: A cross-sectional study was conducted by interviewing cervical cancer patients using the EQ-5D-3L questionnaire. Percentages of patients who reported having problems in each dimension of EQ-5D as well as EQ-5D index score (utility) were calculated. Results: Our findings indicated that the most frequent reported problems were pain/discomfort (67.8%) followed by anxiety/depression (57.5%). The mean of EQ-5D VAS was 75.8 (SD=17.0). The mean (SD) utility scores were 0.85 (0.19), 0.76 (0.20), 0.71 (0.21), and 0.77 (0.13) for cervical cancer patients in stage I, II, III, and IV, respectively. Conclusions: Cervical cancer significantly affects patient HRQOL. Efforts should be made to improve the quality of life of cervical cancer patients especially in terms of pain /discomfort and anxiety/depression reduction.