• Title/Summary/Keyword: $K_e$-factor

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Fuel Cycle Cost Calculation

  • Lee, Chang-Kun;Kang, Jae-Ho
    • Nuclear Engineering and Technology
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    • v.1 no.1
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    • pp.55-66
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    • 1969
  • 1974년도에 가동될 고리 원자력 발전소(Westinghouse 600 MWe PWR)의 핵연료 주기비를 계산했다. 적용한 가정과 가격은 현재 핵 공학계에서 인용하는 것에 기준을 두었고, 한국이라는 국지적 조건을 참작하였다. 계산방식은 가장 적절하다고 생각되는 것을 Normal로 두어, 이 보다 좋거나 나쁜 조건을 고려하였다. 마지막으로 각 Parameter가 주어진 범위 내에서 변하는 것을 Normal과 비교하고 전비용중에서 각각이 차지하는 비율을 검토했는데 그 결과 Uranium 원광비, 성형가공비가 가장 비율이 크고, 그 다음이 이자율, Plutonium Credit, Plant Capacity Factor 등의 순이었다.

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Analysis of Telomerase Activity by HPV E6/E7 Expression in SW13 (인간 파필로마 바이러스 E6/ E7에 의한 Telomerase 활성)

  • Kim, Young-Kwon;Seo, Choong-Won;Kim, Sang-Ha;Park, Yuk-Pheel
    • Korean Journal of Clinical Laboratory Science
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    • v.39 no.1
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    • pp.1-6
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    • 2007
  • Cervical cancer is one of the most prevalent cancers developed in women worldwide, and human papillomavirus(HPV) type 16 is the most common agent linked to human cerivical carcinoma. Viral oncogenes E6 and E7 are selectively retained and expressed in carcinoma cells infected with human papillomavirus type 16 and cooperate with each other in the immortalization and transformation of primary keratinocytes. Because the HPV oncogenesis mechanism was not completely solved, more thorough studies are required. ln the present study, we investigated the telomere independent role of telomerase in HPV oncogenesis, we constructed the E6 mutant, E7, E6/E7 and hTERT over-expressed stable cells with a telomerase negative cell line, SW13. Expressions of inserted genes were measured by RT-PCR. E6, E7 and hTERT genes were well expressed in each cell lines when compared with the control groups. By analyzing the cell morphology under the microscope, hTERT clone size was a smaller than the mock control but oncogene expressed clones had a slightly lengthened marginal region. In addition, hTERT cells also has a tendency of brief dividing time compared to the mock control. To determine whether telomerase activity was associated with a HPV oncogenesis by oncoprotein expression, we performed the PCR based TRAP assay and a Northern blot analysis. In TRAP assay data, telomerase activities in hTERT and oncogene clones increased compared to the mock control. In addition, SW13/E6/E7 cells showed an extremely increased activity compared to the other clones. Induced hTERT mRNA by E6/E7 wasn't, however, detected in Northern blotting. In conclusion, these findings suggest that telomerase activity is closely associated with the HPV oncogenesis and E6/E7 co-expression is a most important factor of telomerase activity.

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Apolipoprotein E Phenotypes and the Relationship Among Lipid Levels, Nutrient Intakes, Lifestyles and Risk Factors Between Subjects with and without Hyperlipidemic Risk (Apolipoprotein E 다형성과 고지혈증 위험 유무에 따른 혈중 지질농도, 영양소 섭취, 생활습관 및 위험요인과의 관계)

  • Lee, Jae-Eun;Cho, Sang-Woon;Kang, Ji-Yeon;Paek, Yun-Mi;Choi, Chang-Sun;Park, Yoo-Kyoung;Choi, Tae-In
    • Journal of Nutrition and Health
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    • v.41 no.5
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    • pp.402-413
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    • 2008
  • This study was performed to investigate Apolipoprotein E phenotypes and the relationship among lipid levels, nutrient intakes, lifestyles and risk factors between subjects with and without hyperlipidemic risk. The data were collected from 675 industrial male workers who had completed annual medical examination. Compared to the normal group, the hyperlipidemic risk group in Apo E3 and E4 had significantly higher BMI (p < 0.05) and showed significantly higher body fat (%), waist circumference and WHR in all types of Apo E (p < 0.05). In addition, the hyperlipidemic risk group had significantly higher total cholesterol, LDL-cholesterol, triglyceride and AI than the normal group in all types of Apo E (p < 0.05). Intakes of protein, calcium, phosphorus, iron, vitamin A, vitamin B1, vitamin B2, vitamin C and niacin in Apo E3 were significantly lower in the hyperlipidemic risk group than in the normal group (p < 0.05). In the logistic regression analysis, after adjustment for other factors, Apo E2 + E4, waist and WHR were the significant risk factors associated with hyperlipidemia, but protein intakes were associated with significantly lower risks of hyperlipidemia (p < 0.05). In conclusion, genetic factor (Apo E2 or Apo E4), anthropometric index and nutrient intake seem to influence hyperlidemic risk. Further studies and efforts will be needed to evaluate the independent relationships among hyperlipidemic risk factors.

Effects of Hydrocarbon Additions on Gas-liquid Mass Transfer Coefficients in Biphasic Bioreactors

  • Silva, Teresa Lopes da;Calado, Vitor;Silva, Nadia;Mendes, Rui L.;Alves, Sebastiao S.;Vasconcelos, Jorge M.T.;Reis, Alberto
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.11 no.3
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    • pp.245-250
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    • 2006
  • The effects of aliphatic hydrocarbons (n-hexadecane and n-dodecane) on the volumetric oxygen mass transfer coefficient $(k_L\;a)$ were studied in flat alveolar airlift reactor and continuous stirred tank reactors (CSTRs). In the flat alveolar airlift reactor, high aeration rates (>2vvm) were required in order to obtain efficient organic-aqueous phase dispersion and reliable $k_La$ measurements. Addition of 1% (v/v) n-hexadecane or n-dodecane increased the $k_La$ 1.55- and 1.33-fold, respectively, compared to the control (superficial velocity: $25.8{\times}10^{-3}m/s$, sparger orifice diameter: 0.5 mm). Analysis of the gas-liquid interfacial area a and the liquid film mass transfer coefficient $k_L$ suggests that the observed $k_La$ increase was a function of the media's liquid film mass transfer. Addition of 1% (v/v) n-hexadecane or n-dodecane to analogous setups using CSTRs led to a $k_La$ increase by a factor of 1.68 and 1.36, respectively (superficial velocity: $2.1{\times}10^{-3}m/s$, stirring rate: 250 rpm). These results propose that low-concentration addition of oxygen-vectors to aerobic microbial cultures has additional benefit relative to incubation in purely aqueous media.

Environmental Factors Related to Enterobiasis in a Southeast Region of Korea

  • Kim, Dong-Hee;Cho, Min Kyoung;Park, Mi Kyung;Kang, Shin Ae;Kim, Bo Young;Park, Sang Kyun;Yu, Hak Sun
    • Parasites, Hosts and Diseases
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    • v.51 no.1
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    • pp.139-142
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    • 2013
  • Pinworm infection can occur through contact with contaminated surfaces followed by ingestion or even through inhalation of infective eggs. We have limited information regarding environmental contamination by eggs of Enterobius vermicularis. In order to determine environmental risk factors associated with the rate of E. vermicularis infection, we investigated possible environmental risk factors using a questionnaire from 46 kindergartens in 3 different cities of the southeast area of Korea. In total, using the cellotape anal swab technique, 3,422 children were examined for E. vermicularis infection. We evaluated E. vermicularis egg of books, educational materials, toys, room door handles, dusts of window edges, desks, chairs, tables, and dusts of classrooms. The overall egg-positive rate for E. vermicularis was 6.0%, and the prevalence of enterobiasis in each kindergarten ranged between 0% and 16.9%. We found that 78.9% of egg positive kindergartens were managed by private foundations, which was significantly higher, compared with kindergartens managed by public foundations or the nation. Compared with public or national kindergartens, most private kindergartens were located in residential areas and the number of children in these areas was significantly higher. In conclusion, numbers of children in kindergartens was found to be an environmental risk factor associated with transmission of enterobiasis in Korea.

Study on TSD Characteristics of LiF ( Mg , Cu , P ) Single Crystal (LiF ( Mg , Cu , P ) 단결정의 TSD 특성에 관한 연구)

  • 도시홍
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.26 no.1
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    • pp.8-13
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    • 1990
  • The microscopic relaxation parameters for the single crystal were measured by using thermally stimulated depolarization (TSD). Initial rise method, various heating rate method and total glow peak method were used for the determination of the activation energy and Debye relaxation time from TSD glow curves. Activation energy, pre-exponential factor and relaxation time for impurity-vacancy dipole reorientation were 0.55eV, 1.97$\times$10 super(-12) sec and 12.19sec in average, respectively. Dielectric dissipation factor for the crystal was calculated from the measured TSD glow curve, its value being about 3$\times$10 super(-2).

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Modeling study on repeat purchase intention on silk products based on the electronic commercial platform

  • Shi, Rui;Li, Gaihang;Liu, Guolian
    • The Research Journal of the Costume Culture
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    • v.20 no.6
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    • pp.937-941
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    • 2012
  • Based on the literature on customer's repeat purchase intention, customer's repeat purchase intention was explored, customer's repeat purchase intention has been a crucial factor influencing consumer behaviors, In this research, the development of models on repeat purchase intention repurchase was indicated. Based on the electronic commerce platform, we focus on the customer's repeat purchase intention on silk products, This paper mainly explores the e-commerce purchase frequency (EPF), customer perceived value (CPV), perceived risk of e-commerce (EPR), and customer satisfaction (CS). The influence of the four factors on repeat purchase intention (RPI) is investigated. In the results, we found that CPV and CS have positive correlations with repeat purchase intention, The EPR has a negative correlation with RPI and has no significant influence on RPI. The result can provide meaningful suggestions for silk product retailers.

Oxidative Stress, Nrf2, and Epigenetic Modification Contribute to Anticancer Drug Resistance

  • Kang, Kyoung Ah;Hyun, Jin Won
    • Toxicological Research
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    • v.33 no.1
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    • pp.1-5
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    • 2017
  • Nuclear factor E2-related factor 2 (Nrf2), a transcription factor, controls the expression of genes encoding cytoprotective proteins, including antioxidant enzymes that combat oxidative and electrophilic stress to maintain redox homeostasis. However, recent studies demonstrated that, in cancer, aberrant activation of Nrf2 by epigenetic alterations promotes high expression of cytoprotective proteins, which can decrease the efficacy of anticancer drugs used for chemotherapy. In this review, we summarize recent findings regarding the relationship between oxidative stress, Nrf2, epigenetic modification, and anticancer drug resistance, which should aid in development of new strategies to improve chemotherapeutic efficacy.

Microstructure and Ferroelectric Properties of Low Temperature Sintering PMN-PNN-PZT Ceramics with Sintering Temperature (저온소결 PMN-PNN-PZT세라믹스의 소결온도에 따른 미세구조 및 강유전특성)

  • Yoo, Ju-Hyun;Lee, Hyun-Seok;Lee, Sang-Ho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.19 no.12
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    • pp.1118-1122
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    • 2006
  • In this study, in order to develop the low temperature sintering multilayer piezoelectric actuator, PMN-PNN-PZT system ceramics were manufactured and their microstructure, ferroelectric and piezoelectric properties were investigated. By increasing sintering temperature, remanent polarization$(P_r)$ was increased due to the increase of sinterability and grain size. However, coercive $field(E_c)$ showed an opposite tendency to remanent polarization owing to the feasibility of domain wall motion. At the sintering temperature of $900^{\circ}C$, dielectric $constant({\varepsilon}_r)$, electromechanical coupling $factor(k_p)$, piezoelectric $constant(d_{33})$ and mechanical quality $factor(Q_m)$ showed the optimal value of 1095, 0.60, 363 and 1055, respectively, for multilayer piezoelectric actuator application.

A Study on the Determination of the Screening Factors for the Tunnel and the Overbridge of the Electric Railway (전기철도 터널 및 고가 구조물의 차폐계수 산정에 대한 연구)

  • Choi, Kyung;Lee, Hyang-Beom;Kim, Hyeong-Seok;Kim, Hak-Cheol
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.67 no.9
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    • pp.1249-1256
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    • 2018
  • For the screening factor of the tunnel and overbridge structure in the electrified railway, the ITU-T regulation denotes only a theoretical estimation method, and the actual numeric values are notified differently by the official announcement of each nations. In this study, the factors which can affect the screening factor are investigated and analysed by FEM and a suitable calculation method based on multi-conductor line theory for the current pre-estimation formula for the induction noise voltage in the national notice is presented. The case studies are performed using the real data of the tunnel and the overbridge of the electrified railway, and a satisfactory formula for the determining of screening factor is derived.