• Title/Summary/Keyword: $K^{+}$ channels

Search Result 4,177, Processing Time 0.031 seconds

The Measurement of Vacuum Pressure for the Multi-Stage Rotors of Disk-Type Molecular Drag Pump (원판형 분자 드래그펌프 다단 회전자에 대한 압력분포 측정)

  • Kwon, Myoung-Keun;Hwang, Young-Kyu
    • Journal of the Korean Vacuum Society
    • /
    • v.18 no.4
    • /
    • pp.272-280
    • /
    • 2009
  • In this study is performed to investigate the pumping characteristics of three-stage disk-type molecular drag pump (DTDP). The experiments are measured using five vacuum pressure gauges in the positions for rotors of DTDP. The experimented DTDP is consisted of three rotors and four stator. In the DTDP, spiral channels of three rotors are cut on the both upper surface and lower surface of a rotating disk, and corresponding stator is a planar disk. The experiments are performed in the outlet pressure range of $0.2{\sim}533\;Pa$. The pressure of each rotors are measured under the various condition of outlet pressure and throughputs, and nitrogen gas is used for test gas. In the numerical study, the pumping characteristics of each rotor are studied for the variation of throughputs in the all rotating channel. Pressure contour and velocity are obtained by the numerical simulation.

Study of Developmet of External Medicine Based on the Result of Prior Study and Folk Remedy Using Scolopendra subspinipes mutilans as a Single Medicine in Korea and China (한국과 중국에서의 오공을 단방으로 사용한 민간요법과 선행연구결과를 기반으로 한 외치 한약제제 개발에 대한 고찰)

  • Kim, Sin Seo;Kim, Myung Dong
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.29 no.3
    • /
    • pp.203-217
    • /
    • 2015
  • Scolpendra subspinipes (centipede) is pungent in flavor, activates the channels to stop pain, and, removes toxins and resolves masses. So it has been used as a folk remedy. We researched folk remedies which used centipede as a single medicine and results of its prior clinical and experimental study, and figured out that centipedes are effective on ulcerative disease, herpes zoster, clavus, insect bite, inflammatory disease, furunculus, pain disease by external therapy, and oral administration is effective on anti-cancer such as hepatoma and uterine cancer, cerebrovascular disease, inhibition of atherosclerosis, sedation of central nervous system, antipyretic action, and anti-inflammation, and centipede Herb-Acupuncture is effective on inflammatory disease and pain disease. Centipede preparation materials for external therapy were sesame oil, perilla oil, vinegar, salt, and, burnt alum. Fumigation of centipede treated paronychia, pertussis, and hemorrhoids. For the external therapy, the way of centipede powder mixing with other materials has been used. It is needed that we use dusted powder to make skin absorb its ingredients more easily, and we study intensely minor ingredients to make centipede components absorbed more effectively and do pharmacological action. Also, fumigation, a kind of another external therapy, is considered to be effective treatment of upper respiratory infection like pertussis, so it needs an in-depth study on centipede fumigation.

Fabrication of Functionally Graded Materials Between P21 Tool Steel and Cu by Using Laser-Aided Layered Manufacturing (레이저 적층조형을 이용한 P21 툴 스틸과 Cu 간 기능성 경사 복합재의 제작)

  • Jeong, Jong-Seol;Shin, Ki-Hoon
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.37 no.1
    • /
    • pp.61-66
    • /
    • 2013
  • With the development of layered manufacturing, thermally conductive molds or molds embedding conformal cooling channels can be directly fabricated. Although P21 tool steel is widely used as a mold material because of its dimensional stability, it is not efficient for cooling molds owing to its low thermal conductivity. Hence, the use of functionally graded materials (FGMs) between P21 and Cu may circumvent a tradeoff between the strength and the heat transfer rate. As a preliminary study for the layered manufacturing of thermally conductive molds having FGM structures, one-dimensional P21-Cu FGMs were fabricated by using laser-aided direct metal tooling (DMT), and then, material properties such as the thermal conductivity and specific heat that are related to the heat transfer were measured and analyzed.

Report on the Field Excursion, 'Tsunami impact on the coastal zone of Thailand' ('태국 연안역의 지진해일 충격' 야외답사 보고)

  • CHANG SE WON;LEE HEE-IL;PARK YOUNG SOO
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
    • /
    • v.10 no.3
    • /
    • pp.171-180
    • /
    • 2005
  • Related to the tsunami impact caused by the 2004 Sumatra earthquake, field excursion of the title 'Tsunami impact on the coastal zone of Thailand' was carried out along the damaged coasts of Thailand fur three days. The damaged coastal zones along the Andaman Sea coasts of Thailand are classified into the severely damaged, the moderately damaged, and the slightly damaged coastal zone by the degree of damage. Channels of the river- mouths were widen, and the beach sands were eroded, transported, and then redeposited in the near shore or in the back beach area. Field excursion stops were 12 in the representative areas like Phang Nga province, the severely damaged coastal zone and Phuket Island, the slightly damaged coastal zone. In this report, the geo-logical effects on the coastal zone of Thailand by tsunami will be mainly illustrated by the satellite data before and after tsunami and the photographs taken during the field excursion.

On Transmission Scheduling with Tuning-Limited Transmitters in WDM Star Networks (파장 분할 방식 성형 통신망에서 조정 제약을 갖는 전송기를 이용한 전송 스케줄링)

  • Choi, Hong-Sik;Lee, Kyung-Joon;Kim, Jin
    • Journal of KIISE:Information Networking
    • /
    • v.29 no.2
    • /
    • pp.129-140
    • /
    • 2002
  • In this paper, we consider the problem of packet transmission in a wavelength division multiplexed(WDM) optical network. Our network model assumes that receivers are fixed-tuned and transmitters are tunable such that optical lasers assigned to transmitters have limited access to the network bandwidth: hence each node must be equipped with multiple optical lasers and/or multiple optical filters in order to maintain a single-hop network. We first analyze scheduling all-to-all packet transmissions and present optimum scheduling for all-to-all packet transmissions. We then extend the analysis to the case of arbitrary traffic demands. We show that the scheduling with arbitrary traffic demand is NP-hard. A heuristic algorithm based on list scheduling is presented. The upper bound so obtained is compared with the lower bound and provides performance guarantees with arbitrary demands. The result are applicable to arbitrary tuning delay, arbitrary number of wavelength channels and optical lasers of arbitrary tuning ranges.

Establishment of Equi-Distance River Cross Section and Finite Element Mesh Using ArcView and Observed Cross Section (ArcView와 실측단면을 이용한 등간격 하도단면 및 유한요소망 구축)

  • Choi, Seung-Yong;Han, Kun-Yeun
    • Journal of the Korean Association of Geographic Information Studies
    • /
    • v.12 no.4
    • /
    • pp.95-112
    • /
    • 2009
  • The river cross section in the input/output data which are needed in the area of river flow analysis is very important factor. The bottom elevation of actual river cross section has to be correctly reflected to obtain correct results when two dimensional flow analysis is conducted for natural river. But to reflect virtually the bottom elevation of river cross section is impossible. The objective of this study is to suggest a method for creating equi-distance river cross section by using both HEC section and ArcView and constructing the finite element mesh. The main channels of Han and Nakdong river were selected and equi-distance river cross sections constructed in this study have shown good agreement with the observed river cross sections. In addition, high quality finite element meshes can be applied to many areas of study such as finite element analysis for water quality and two dimensional flow analysis using the suggested method for equi-distance river cross sections in this study.

  • PDF

Condensation Heat Transfer and Pressure Drop of R-134a in the Oblong Shell and Plate Heat Exchanger

  • Park Jae-Hong;Kim Young-Soo
    • International Journal of Air-Conditioning and Refrigeration
    • /
    • v.12 no.3
    • /
    • pp.158-167
    • /
    • 2004
  • Condensation heat transfer experiments were conducted with a oblong shell and plate heat exchanger without oil in a refrigerant loop using R-134a. An experimental refrigerant loop has been developed to measure the condensation heat transfer coefficient $h_r$ and frictional pressure drop ${\Delta}p_f$ of R-134a in a vertical oblong shell and plate heat exchanger. Four vertical counter flow channels were formed in the oblong shell and plate heat exchanger by four plates having a corrugated sinusoid shape of a $45^{\circ}$ chevron angle. The effects of the refrigerant mass flux, average heat flux, refrigerant saturation temperature and vapor quality were explored in detail. Similar to the case of a plate heat exchanger, even at a very low Reynolds number, the flow in the oblong shell and plate heat exchanger remains turbulent. The results indicate that the condensation heat transfer coefficients and pressure drops increase with the vapor quality. A rise in the refrigerant mass flux causes an increase in the $h_r\;and\;{\Delta}p_f$. Also, a rise in the average heat flux causes an increase in the $h_r$. But the effect of the average heat flux does not show significant effect on the ${\Delta}p_f$. On the other hand, at a higher saturation temperature, both the $h_r\;and\;{\Delta}p_f$. found to be lower. Based on the present data, the empirical correlations are provided in terms of the Nusselt number and friction factor.

A study on the profitability and marketing costs of seed potato farming in Bangladesh (방글라데시 씨감자 농가의 유통비용 및 수익성에 관한 연구)

  • Tabassum, Nazia;Kim, Chul-Won
    • Food Science and Preservation
    • /
    • v.16 no.4
    • /
    • pp.490-498
    • /
    • 2009
  • This study attempted to examine the profitability and marketing costs of seed potato under contract farming system of BADC (Bangladesh Agricultural Development Corporation) with the help of primary and secondary data. Total 45 contract farmers were randomly selected. Attempts were made to calculate costs, returns and profitability of seed potato production under contract farming system, and to identify marketing channels of seed potato. The field level data were collected by a farm survey during the months of April 2005 through direct interviews with contract farmers and registered dealers using a structure survey questionnaire. The results showed that the gross return per hectare was Tk. 252,464 for all categories of farms. Cost of seeds, fertilizers, pesticides, irrigation and human labor were critical inputs for profitability of seed potato. Cobb-Douglas production function analysis was used to determine the effects of the key variables to seed potato production under contract farming system. The elasticity of seed potato production was at 0.727 for all categories of farms. The findings exhibited that the summation of elasticity of different inputs for seed potato production was less than one, implying that the production function exhibited decreasing returns to scale. Registered dealers and Upazila Sales Centers were involved in seed potato marketing formed a straightforward marketing channel. The total marketing costs of registered dealers were Tk. 759.49 per ton of seed potato. The net marketing margin of registered dealers was estimated at Tk. 465.51 per ton of seed potato. The selected contract farmers and registered dealers faced a number of problems and some of recommendations were suggested.

Naringenin inhibits pacemaking activity in interstitial cells of Cajal from murine small intestine

  • Kim, Hyun Jung;Kim, Byung Joo
    • Integrative Medicine Research
    • /
    • v.6 no.2
    • /
    • pp.149-155
    • /
    • 2017
  • Background: Naringenin (NRG) is a common dietary polyphenolic constituent of fruits. NRG has diverse pharmacological activities, and is used in traditional medicine to treat various diseases including gastrointestinal (GI) disorders. Interstitial cells of Cajal (ICCs) are pacemaker cells of the GI tract. In this study, the authors investigated the effects of NRG on ICCs and on GI motility in vitro and in vivo. Methods: ICCs were dissociated from mouse small intestines by enzymatic digestion. The whole-cell patch clamp configuration was used to record pacemaker potentials in cultured ICC clusters. The effects of NRG on GI motility were investigated by calculating percent intestinal transit rates (ITR) using Evans blue in normal mice. Results: NRG inhibited ICC pacemaker potentials in a dose-dependent manner. In the presence of tetraethylammonium chloride or iberiotoxin, NRG had no effect on pacemaker potentials, but it continued to block pacemaker potentials in the presence of glibenclamide. Preincubation with SQ-22536 had no effect on pacemaker potentials or on their inhibition by NRG. However, 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one blocked pacemaker potential inhibition by NRG. In addition, L-NG-nitroarginine methyl ester blocked pacemaker potential inhibition by NRG. Furthermore, NRG significantly suppressed murine ITR enhancement by neostigmine in vivo. Conclusion: This study shows NRG dose-dependently inhibits ICC pacemaker potentials via a cyclic guanosine monophosphate/nitric oxide-dependent pathway and $Ca^{2+}$-activated $K^+$ channels in vitro. In addition, NRG suppressed neostigmine enhancement of ITR in vivo.

Extracting Neural Networks via Meltdown (멜트다운 취약점을 이용한 인공신경망 추출공격)

  • Jeong, Hoyong;Ryu, Dohyun;Hur, Junbeom
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.30 no.6
    • /
    • pp.1031-1041
    • /
    • 2020
  • Cloud computing technology plays an important role in the deep learning industry as deep learning services are deployed frequently on top of cloud infrastructures. In such cloud environment, virtualization technology provides logically independent and isolated computing space for each tenant. However, recent studies demonstrate that by leveraging vulnerabilities of virtualization techniques and shared processor architectures in the cloud system, various side-channels can be established between cloud tenants. In this paper, we propose a novel attack scenario that can steal internal information of deep learning models by exploiting the Meltdown vulnerability in a multi-tenant system environment. On the basis of our experiment, the proposed attack method could extract internal information of a TensorFlow deep-learning service with 92.875% accuracy and 1.325kB/s extraction speed.