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Effects of Allogeneic Blood Transfusion in Patients with Stage II Colon Cancer

  • Meng, Jin;Lu, Xiao-Bo;Tang, Yuan-Xin;Sun, Gong-Ping;Li, Xin;Yan, Yi-Fei;Liang, Gao-Feng;Ma, Si-Ping;Li, Xiao-Xia
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.347-350
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    • 2013
  • The aim of the present study was to determine whether allogeneic red blood cell transfusions showed a deleterious effect and what might be preoperative risk factors for blood transfusion in patients with TNM stage II colon cancer. Total 470 patients who fulfilled inclusion criteria were selected for a further 10-year follow-up study. We found that there were statistical significance between non-transfused and transfused group in mortality (P=0.018), local recurrence (P=0.000) and distant metastasis (P=0.040). Local recurrence and distant metastasis between 1 to 3 units and more than 3 units group did not show any significant differences. There was no difference in survival rate between non-transfused and 1 to 3 units group (log rank=0.031, P=0.860). The difference between different blood transfusion volume in transfused patients was found (78.77% vs 63.83%, P=0.006). Meanwhile, the significant difference of survival rate was existed between non-transfused group and more than 3 units group (84.83% vs 63.83%, P=0.002 ). Univariate analysis showed the following 3 variables to be associated with an increased risk of allogeneic blood transfusions: preoperative CEA level (P<0.05), location of tumor (P<0.01) and diameter of tumor (P<0.01). Multivariate analysis revealed that location of tumor and diameter of tumor are two independent factors for requirement of perioperative transfusions. Therefore, allogeneic transfusion increase the postoperative tumor mortality, local recurrence and distant metastasis in patients with stage II colon cancer. The postoperative tumor mortality, local recurrence and distant metastasis were not associated with the blood transfusion volume. The blood transfusion volume was associated with the survival rate. Location of tumor and diameter of tumor were the independent preoperative risk factors for blood transfusion.

Estimation of Fish Species Diversity of Small and Medium Rivers of Korea with Fish Species-Habitat Relationship Models od GAP (GAP기법을 이용한 종소하천의 어류종다양성 예측기법 연구)

  • 박종화;홍성학
    • Spatial Information Research
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    • v.6 no.1
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    • pp.91-102
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    • 1998
  • The objectives of this research were to develop fish-habitat relationship models which can be used to estimate fish species riclmess of small and medium rivers in Korea, and test the accuracy of the models. The models are based on the Aquatic GAP Analysis model in the New York Cooperative Fish & Wildlife Research Unit (19%), and they employ three habitat factors; river size, physical habitat, and water quality of each river segment. Model 1 and model II are based on the water quality standard for life support of EP A and the water quality class of Korea, respectively. Test sites for this study include one urban stream and three less spoiled tributaries of the Han River. The results of this research can be summarized as follows. First, the number of habitat types identified by model I and model II are nine and 14, respectively. Second, the average accuracy of the three distribution maps of rare or endangered fish species are 80.6% (model 1) and 81.2% (model II). Third, the accuracy of fish species richness are 94% (model 1) and 95% (model II), and the water quality is the most important factor affecting fish species richness. Fourth, the accuracy of fish species list are 50.5% (model 1) and 68.7% (model II), but the accuracy of less spoiled stream segments and that of polluted stream segments are 67.1% and 86.5%, respectively. Finally, it can be concluded that the overall performance of model II is better than that of model I at our test sites.

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Effects of FDA Treatment after Vitrified Freezing on In Vitro Fertilization and Development of Porcine Follicular Oocytes II. Effect of Degree of Cumulus Cell Attachment on In Vitro Maturation of Porcine Follicular Oocytes (돼지 미성숙 난포란의 유리화 동결융해후 FDA 처리가 체외수정과 배 발육에 미치는 영향 II. 난구세포의 부착정도가 돼지난포란의 체외성숙에 미치는 영향)

  • 김영훈;김중계
    • Journal of Embryo Transfer
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    • v.11 no.3
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    • pp.233-240
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    • 1996
  • This study was carried out to determine the effect of cumulus cell attachment and various factors on in vitro maturation of pig foflicular oocytes. Oocytes with various configuration of cumulus cell mass were collected ftom ovaries of mature gilts by asperating with syringe equipped with needles of different gauges, follicle size and with or without cumulus cells. They were cultured in TCM-199 mediun containing FGS(fetal calf serum) for 30~48 hours in incubator with air containing 5% $CO_2$ at 38.5$^{\circ}C$. Mter orcein staining at in vitro maturation condition, GV, GVBD, anaphase, telophase and M II were observed. Results are surumarized as follows: 1. Recovery rates were 55.8, 55.5 and 34.4% when the cumulus-compacted oocytes were collected with 18, 21, 26 gauge needles of syringes, respectively. 2. 79% of oocytes with compacted cumulus cells were at GV stage and most of the oocytes with partially denuded and denuded cumulus cells were from GVBD to M- II stages. 3. Percentage of mature oocytes among those which are follicular diameter of 1~2, 3~6 and over 6 mm was 42.6, 53.2 and 60.8%, respectively. 4. Percentage of mature oocytes among those which are compacted, partially denuded and denuded was 60.5, 46.2 and 35.4% respectively. 5. Percentage of mature oocytes in co-cultured with monolayers of cumulus cells was higher (57.1%) than that found with oocytes cultured alone (53.4%).

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Studies on the Improvement of Embryo Transfer Efficiency in Korean Cattle II. Effect of Recipient Conditions on Pregnancy Rate after Embryo Transfer (한우에서 수정란 이식의 효율 증진에 관한 연구 II. 수란우의 조건이 이식 후 수태율에 미치는 영향)

  • 김흥률;김덕임;박노형;김창근;정영채;윤종택;전광주
    • Journal of Embryo Transfer
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    • v.13 no.1
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    • pp.61-67
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    • 1998
  • This study was carried out to establish an effective system for embryo transfer techniques by analyzing several factors affecting in-vivo embryo transfer in Korean cattle. Embryos produced in-vivo were transferred into a total of 301 recipients The results obtained in studies on the factors affacting pregnancy rate after embryo transfer by condition of recipients were as follows ; 1. The pregnancy rate by age and parity of recipients showed high in 5~8 and over 12 years old(72.7~73.9%), and 3rd~4th parity(82.1%) for fresh embryos(P<0.05). The pregnancy rate did not differ by age and parity of recipients in frozen embryos. The pregnancy rate of frozen embryos tended to be similar to that of fresh embryos(38.5% and 25.0~36.7%). 2. The number of observation for normal estrus cycles of recipients did not differ In pregnancy rate between one and 2 times in fresh embryos(64.9%, 69.8%). The pregnancy rate by transferred frozen embryos showed significantly higher after 2 times of observation(P<0.05, 16.3%, 37.5%). The pregnancy rate by days open did not differ between fresh and frozen embryos. But the pregnancy rate was slightly higher in 12 months and 6 months of days open for fresh and frozen embryos, respectively(70.1~71.1% and 24.5%, respectively). 3. The pregnancy rate of transferred fresh and frozen embryos into right and left side of uterine horn did not differ(62.1% : 65.9% 25.0% : 24.3%, respectively). The pregnancy rate by the grade of CL was not different in fresh embryos, but the pregnancy rate was significantly higher in the grade A than B for frozen embryos(P<0.01, 43.2%, 16.2%).

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A STUDY ON THE NOSE PROFILE WITH RESPECT TO THE SKELETODENTAL PATTERN (악안면 골격 유형에 따른 비부 형태에 대한 연구)

  • Tae, Ki-Chul;Kim, Sang-Cheol
    • The korean journal of orthodontics
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    • v.24 no.4 s.47
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    • pp.861-869
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    • 1994
  • The purpose of this study was to investigate the relationship of nose profile with respect to skeletodental pattern, by measured and analyzed statistically the lateral cephalograms of 95 females (13 to 30 years old). Tge results were summerized as follows ; 1. The antero-posterior factors of the nose - nasofrontal angle, nasofacial angle, and dorsal length / ala length ratio were different among the malocclusion groups 2. There were no significant correlation between the the vertical nose factors and the skeletal factors 3. The Class I groups had a straight nose profile , the Class II groups had a convex profile ; the Class III groups had a concave profile.

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Clinical Analysis of Recurrent Ppneumothorax -A Report of 52 Cases- (재발성 기흉의 고찰 -52 례 보고-)

  • 조재호
    • Journal of Chest Surgery
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    • v.28 no.2
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    • pp.166-169
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    • 1995
  • Pneumothorax, a frequently encountered disease in the clinic, has been interesting to surgeons for it`s high recurrence rate. 52 patients with a second attack of pneumothorax at our hospital in a 24 month period were evaluated especially for the risk factors of recurrence. The results were as follows:1. Patients after operative treatment[21 cases There were no postoperative complications and recurrence.2. Patients with tube drainage or conservative treatment [31 cases [i Overall recurrence rate was 45.2 %. [ii Suggestive risk factors for the recurrence were: age above 30 years, short period of thoracostomy less than six days. And other factors such as male, right lung, higher level of lung collapse were thought to be followed further more.

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Reliability Equivalence Factors of Non-identical Components Series System with Mixture Failure Rates

  • Mustafa, A.;El-Desouky, B.S.;El-Dawoody, M.
    • International Journal of Reliability and Applications
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    • v.10 no.1
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    • pp.17-32
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    • 2009
  • The aim of this work is to generalize reliability equivalence technique to apply it to a system consists of n independent and non-identical components connected in series system, that have mixing constant failure rates. We shall improve the system by using some reliability techniques: (i) reducing some failure rates; (ii) add hot reduncy components; (iii) add cold reduncy components; (iv) add cold reduncy components with imperfect switches. We start by establishing two different types of reliability equivalence factors, the survival equivalence (SRE), and mean reliability equivalence (MRE) factors. Also, we introduced some numerical results.

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Prevalence of Abdominal Obesity and Associated Factors among Korean Adults: The 2001 Korean National Health and Nutrition Examination Survey (한국 성인의 복부비만 빈도와 관련 인자: 2001 국민건강영양조사)

  • Chung, Hae-Rang
    • Journal of Nutrition and Health
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    • v.39 no.7
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    • pp.684-691
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    • 2006
  • Abdominal obesity (AO) is a strong risk factor for type 2 diabetes and cardiovascular disease, which has shown a remarkable increase in Korea. This study aimed to identify prevalence of AO and related risk factors in Korean adults. A total of 5,132 men and women aged 20-85 years old from the 2001 Korean National Health and Nutrition Examination Survey were included in the analyses. AO was defined as waist circumference >=90 cm in men and >=85 cm in women as proposed by Korean Society of Obesity. Multiple logistic regression was carried out to identify risk factors for AO. Three models were specified: (i) demographic and socioeconomic factors (model 1: age, education, poverty income ratio, employment), (ii) lifestyle factors and covariates (model 2: physical activity, cigarette smoking, alcohol consumption, dietary quality, type 2 diabetes, co-morbidity) and (iii) demographic, socioeconomic and lifestyle factors (model 3). The prevalence of AO was 24.1 % in men, 23.5% in women. High poverty income ratio in men and low education attainment in women were risk factors for AO in model. 1. There was a significant association of AO with alcohol consumption, physical inactivity and dietary quality in men, alcohol consumption and cigarette smoking in women. These factors except alcohol consumption in men became insignificant in model 3. This findings underscore the importance of developing AO prevention programs in Korea that target the at risk groups identified in this study. A program focusing on low income men or less educated women would be more efficient.

Analysis of Risk Factors in Children with Suspected Developmental Delays on the Denver Developmental Screening Test

  • Bang, Kyung-Sook
    • Child Health Nursing Research
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    • v.14 no.3
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    • pp.261-268
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    • 2008
  • Purpose: This study was conducted to estimate the prevalence of questionable development according to developmental screening testing for children, and to explore biological and environmental risk factors of developmental delays. Method: The study participants were 153 children under two years of age. A questionnaire and Home Observation for measurement of the Environment (HOME) inventory were used to collect data, and Korean Denver II was administered. Results: The overall prevalence of questionable development was 11.1%. Significant differences in biological factors between the normal development group and questionable development group were the rate of prematurity, twins, the educational level of mother and father's and the presence of an illness in the mother (p<.10). Maternal acceptance in HOME was significantly different between the two groups. The factors related to questionable development that were significant in the logistic regression analysis were prematurity (OR=3.56, p=.026), and maternal acceptance in HOME score (OR=.629, p=.028). Conclusion: Early developmental screening tests seem necessary for all children, especially for prematurely born children. Also, child rearing environments were identified as significant factors in the development of all children. These findings suggest that the HOME scores might be useful in identifying children at risk for developmental delays, and that interventions for these children will probably be more effective if their mothers are helped to provide a more appropriate social environment.

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Improved survival rate with decreased neurodevelopmental disability in extreme immaturity (초극소저출생체중아의 생존율 향상에 따른 장기 신경발달 장애의 감소)

  • Jeon, Ga Won;Kim, Myo Jing;Kim, Sung Shin;Shim, Jae Won;Chang, Yun Sil;Park, Won Soon;Lee, Mun Hyang
    • Clinical and Experimental Pediatrics
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    • v.50 no.11
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    • pp.1067-1071
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    • 2007
  • Purpose : The aim of this study was to determine whether improved survival of extremely low birth weight infants (ELBWI) was associated with decreased neurodevelopmental disability later in life, and also to identify the factors influencing this disability. Methods : ELBWI admitted to the neonatal intensive care unit of Samsung Medical Center, survived, and followed up until the corrected age of 18 months were enrolled. They were divided into two groups according to admission time: period I (1994-1999, n=36) and period II (2000-2004, n=98). Clinical data were collected retrospectively from the medical records. Results : Survival rates increased from 60.0% to 74.7%, cerebral palsy rates decreased from 22.2% to 8.2% and catch-up growth rate increased from 25.0% to 51.0% during period I and II. Despite less gestational age and birth weight, ELBWI during period II had less periventricular leukomalacia (PVL), sepsis and bronchopulmonary dysplasia compared to period I. The highest risk factors for cerebral palsy were intraventricular hemorrhage (IVH) (${\geq}$Grade III), failure of catch-up growth and PVL. Conclusion : In summary, improved viability was associated with decreased neurodevelopmental disability in ELBWI. Improved neonatal care with resultant decrease in PVL and IVH, and better nutritional support seem to be primarily responsible for this improved outcome.