• Journal of the Korean Society of Safety
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• v.33 no.2
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• pp.145-151
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• 2018

In this study, the track-bridge interaction analysis was performed using an analytical model considering the track structure, thereby taking into account the linear conditions (R=650 m, cant variation $160{\pm}60mm$) and the dynamic characteristics of the bridge. As a result of the study, the allowable speed on the example bridge considered was calculated at 200 km/h based on vertical deflection, vertical acceleration, and irregularity in longitudinal level, but was also evaluated at 170km/h based on the coefficient of derailment, wheel load reduction, and lateral displacement of the rail head. It is considered desirable to set the speed 170km/h to the speed limit in order to secure the safety of both the bridge and the track. It is judged that there will be no problems with ensuring rail protection and train stability in the speed band.

• Journal of Food Hygiene and Safety
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• v.28 no.2
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• pp.168-173
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• 2013

This study was carried out to develop and validate predictive models of E. coli O157:H7 growth. Growth data of E. coli O157:H7 in Paprika were collected at 12, 24, 30 and $36^{\circ}C$. The population increased into 3.0 to 3.8 log10 CFU/g within 4 days, then continued to increase at a slower rate through 10 days of storage at $12^{\circ}C$. The lag time (LT) and maximum specific growth rate (SGR) obtained from each primary model was then modeled as a function of temperature using Davey and square root equations, respectively. For interpolation of performance evaluation, growth data for a mixture of E. coli O157:H7 were collected at time intervals in paprika incubated at the different temperatures, which was not used in model development. Results of model performance for interpolation data demonstrated that induced secondary models showed acceptable goodness of fit. Relative errors in the LT and SGR model for interpolation data (18 and $27^{\circ}C$) was 100%, which show acceptable goodness of fit and validated for interpolation. The primary and secondary models developed in this study can be used to establish tertiary models to quantify the effects of temperature on the growth of E. coli O157:H7 in paprika.

• International Journal of Safety
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• v.4 no.2
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• pp.43-46
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• 2005

The construction workers might be at the risk of many occupational injuries and illnesses. To protect workers from various hazards, industrial health and hygiene systems were specified for the construction workers by law. It is important to know the actual health and safety(H&S) conditions by tasks and the characteristics of injuries and illnesses of construction workers. This study was designed to investigate the actual conditions of construction workers exposed to various harmful substances and work elements including evaluation of health status of each worker and general H&S system. Questionnaire was sent to 600 construction workers nationwide and totally 367 people responded to it having 61.67% of response rate. The common construction hazards were dust(29.6%), noise(19.3%), repetitive motions(12.0%), handling excessive heavy materials(11.2%) in order. The repetitive motions and handling heavy materials related to muscle disorders accounted for 23.2%. The accident and injury types were in order of overexertion, falling, overturning, dropping or flying, electric shock, collision, etc.

• Journal of Environmental Science International
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• v.23 no.3
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• pp.483-492
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• 2014

DNA damage such as genotoxicity was identified with comet assay, which blood cell of a marine parrot fish (Oplegnathus fasciatus) was exposed to an acidified seawater, lowered pH gradient making of $CO_2$ gas. The gradient of pH were 8.22, 8.03, 7.81, 7.55 with control as HBSS solution with pH 7.4. DNA tail moment of fish blood cell was $0.548{\pm}0.071$ exposed seawater of pH 8.22 condition, on the other hand, DNA tail moment $1.601{\pm}0.197$ exposed acidified seawater of pH 7.55 lowest condition. The approximate difference with level of DNA damage was 2.9 times between highest and lowest of pH. DNA damage with decreasing pH was significantly increased with DNA tail moment on blood cell of marine fish (ANOVA, p < 0.001). Ocean acidification, especially inducing the leakage of sequestered $CO_2$ in geological structure is a consequence from the burning of fossil fuels, and long term effects on marine habitats and organisms are not fully investigated. The physiological effects on adult fish species are even less known. This result shown that the potential of dissolved $CO_2$ in seawater was revealed to induce the toxic effect on genotoxicity such as DNA breakage.

• Journal of the Korean Society of Safety
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• v.11 no.4
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• pp.64-71
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• 1996

Detonation phenomena of $C_2H_2$were invesgated using the various shock tube. To study the detonation characteristics according to the composition of $C_2H_2-0_2$$_2$ and $C_2H_2$-air mixtures, the composition were varied from 5 to 90% and 5 to 50% of acetylene each other. A spiral ring was installed in the shock tube to study the effect of obstacles in DDT phenomena. Detonation velocities were measured using the photodiode, and the DDT phenomena was visualized using the high speed schlieren photograph. From the experimental result, it was found that the detonation velocity was most high near the 1. 8times the stoichiometric ratio of acetylene. And from the visualization of DDT phenomena, it was found that the detonation wave was strengthened throuth the pile up of small compression wave of burned gas. And the obstacles in shock tube accelerate the detonation reaction by turblent effect of flammable gas mixture.

• Journal of the Korean Society of Safety
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• v.20 no.4 s.72
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• pp.54-62
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• 2005

This Study is to find out how RC beam mixed with sawdust acts comparing with normal beam without sawdust mixture, and how they can be applied to the actual structural frame, despite a Int that they are mixed with waste material : saying sawdust. ED3H1, ED3H2, ED5H1, ED5H2, ED3H1UB, ED5H1UB, ED3H2L, ED5H2L and Normal without sawdust mixture are main factor to be tested here in order to apply them to the actual case. D and H means diameter 3cm or 5cm, and holes one and two respectively. And all variables are tested with each two for one variables. Test results are compared using crack diagrams and strain & loads. There are eleven(11)% capacity decrease between ED 3H1 and ED5H1 in rebar, strain. Left and right side crack shapes are much similar in variable ED3H2L having maximum capacity 14.5 tone. ED5H2L having maximum capacity thirteen(13)tone, in case of normal 19.6 tone. Two holes in beam rather on the longitudinal direction than on the forcing direction can be more effective to keep the original capacity of the beam because this case can distribute load more uniformly. There is 33% capacity decreased in case of diameter five(5)cm, compared to diameter three(3)cm. Two holes give thirty nine(39) percent capacity decrease than one of diameter three(3)cm.

• Toxicological Research
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• v.17 no.1
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• pp.7-9
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• 2001

The quantitative assessment of the penetration of organic solvents through skin is necessary for the evaluation of health hazards in occupational environments. We investigated the rate of dermal penetration when mixed or single forms of organic solvents were placed into a diffusion cell in vitro or into an experimental animal in vivo. The diffusion rates of methanol. toluene, and styrene were 6.07, 0.129, and 0.046 mg/$cm^2$/h, respectively. When skin was exposed to the mixed solvent of methanol and toluene, the penetration rate of toluene did not change significantly (0.110 mg/$cm^2$/h). However, the rate of methanol penetration increased to 43.90 mg/$\textrm{cm}^2$/h. The penetration rate of methanol also increased significantly to 54.69 mg/$cm^2$/h by mixing it with styrene. The concentration of methanol in the blood was monitored during the epicutaneous exposure in rats. The blood concentration of methanol was increased by mixing methanol with toluene as seen in the in vitro experiments. These results showed that the penetration rate of organic solvents would be enhanced by mixing them with other solvents.

• Journal of the Korean Society of Safety
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• v.24 no.6
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• pp.144-149
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• 2009

The safety assessment for facility industry is now being periodically performed in Korea. For the purpose of scientific safety management, QRA(Quantitative Risk Assessment) is also being performed, and reliability data of the facilities is essential to perform the assessment. The necessary reliability data for QRA have been generally announced the values in other process industries, which results in the drop of risk reliability. The most appropriate method is to perform a direct reliability analysis towards the facilities undergoing safety assessment. In this study, the distinction between homogeneous sample estimation and multi-sample estimation of reliability data clarify using 2-Bayes theory.

• Nuclear Engineering and Technology
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• v.54 no.2
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• pp.442-448
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• 2022

Intermediate-level radioactive waste (ILW) is not subject to legal approval for cave disposal in Korea. To solve this problem, a spent resin treatment device that separates ¹⁴C-containing resin from zeolite/activated carbon and desorbs ¹⁴C through a microwave device has been developed. In this study, we evaluated the radiological safety of the operators performing repair work in the event of a failure in such a device treating 1 ton of spent resin mixture per day. Based on the safety evaluation results, it is possible to formulate a design plan that can ensure the safety of workers while developing a commercialized device. When each component of the resin treatment device can be repaired from the outside, the maximum and minimum allowable repair times are calculated as 263.2 h and 27.7 h for the ¹⁴C-detached resin storage tank and zeolite/activated carbon storage tank, respectively. For at least 6 h per quarter, the worker's annual dose limit remains within 50 mSv/year; further, over 5 years, it remained within 100 mSv. At least 6 h of repair time per quarter is considered, under conservative conditions, to verify the radiological safety of the worker during repair work within that time.

• Journal of Ginseng Research
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• v.36 no.3
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• pp.242-247
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• 2012

Chondrocyte apoptosis has been recognized as an important factor in the pathogenesis of osteoarthritis (OA). Hydrogen peroxide ($H_2O_2$), which produces reactive oxygen species, reportedly induces apoptosis in chondrocytes. The ginsenoside $Rb_1$ (G-$Rb_1$) is the principal component in ginseng and has been shown to have a variety of biological activities, such as anti-arthritis, anti-inflammation, and anti-tumor activities. In this study, we evaluated the effects of G-$Rb_1$ on the mitochondrial permeability transition (MPT) and caspase-3 activity of chondrocyte apoptosis induced by $H_2O_2$. Cultured rat articular chondrocytes were exposed to $H_2O_2$ with or without G-$Rb_1$ and assessed for viability, MPT, Bcl-xL/Bax expression, caspase-3 activity, and apoptosis. The co-treatment with G-$Rb_1$ showed an inhibition of MPT, caspase-3 activity, and cell death. Additionally, the levels of the apoptotic protein Bax were significantly lower and the levels of the anti-apoptotic protein Bcl-xL were higher compared with $H_2O_2$ treatment alone. The results of this study demonstrate that G-$Rb_1$ protects chondrocytes against $H_2O_2$-induced apoptosis, at least in part via the inhibition of MPT and caspase-3 activity. These results demonstrate that G-$Rb_1$ is a potentially useful drug for the treatment of OA patients.