• 미생물학회지
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• 제46권2호
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• pp.148-151
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• 2010

동물성 식품 유래 장구균의 에리스로마이신 내성 유전자형 및 표현형을 분석하고자 하였다. 경기북부지역의 축산 농가 15곳으로부터 원유 시료 378개를 분양받아 본실험에 사용하였으며 에리스로마이신 내성 장구균 분리에 사용하였다. 총 110균주의 장구균이 분리 되었으며 이중 E. faecalis가 101균주, E. avium이 7균주, E durans가 2균주였다. 에리스로마이신에 대한 내성 비율은 65.45%였으며 $MIC_{50}$은 16 ${\mu}g$/ml, $MIC_{90}$은 64 ${\mu}g$/ml이었다. 분리된 장구균 110균주 모두 erm(B) 유전자를 소유하고 있었으며 75.45%인 83균주가 mef(A)를 소유하고 있음을 확인하였다. 표현형 분석에 따르면 지속성 내성($cMLS_B$)을 나타내는 균주는 95균주(86.36%)였으며 유도내성 ($iMLS_B$)을 보이는 균주는 15균주(13.34%)였다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 1998년도 제14회 학술발표회 논문개요집
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• pp.109-109
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• 1998

최근 들어 MOCVD 법으로 성장시킨 GaN, InGaN, AIGaN를 이용한 광소자 ( (LED, LD)와 전자소자(FET, MODFET)에 대한 관심이 고조되면서, MOCVD 법 을 이용한 GaN 중심의 질화물 반도체 성장에 관심이 집중되고 있다. 금번 실험에 사용된 MOCVD 장비는 수직형 MOCVD 장비이다. 특히, wafer c carner를 1$\alpha$)() rpm이상의 고속으로 회전시킬 수 있는 장치로서 원료 가스의 반웅 기 내에서의 흐름을 균일하게 하여 uniformity가 높은 질화물 반도체를 성장시킬 수 있다 .. GaN 에피충은 c-plane 사파이어를 기판으로 하여 11 00 "C 이상의 고온 에서 수소를 이용하여 기판을 cleaning하고, 500 "C 부근에서 핵생성충올 성장시 킨 후 1050 "C에서 trimethylgallium(TMGa)과 NI-h를 이용하여 성장시켰다. n n -GaN를 성장시키기 위해서는 SiH4을 사용하였으며, InGaN의 경우는 t trimethylindium(TMIn)을 In원 료 가스로 하여 635 - 725 "C 범 위 에 서 성 장시 켰 다. 성 장된 undoped GaN, n-GaN, InGaN는 X -ray di잔raction(XRD), H떠l m measurement, Photoluminescence(PU동올 이용하여 결정성과 전기적 및 광학적 특성올 고찰하였다 .. 2ttm 두께로 성장된 undoped G값V박막의 경우 Hall 측정결과 6 6 X lOI6/e며 정도의 낮은 도핑 농도를 보였으며, V!lII ratio(2500 - 5000)증가에 따라 결정성이 향상됨을 GaN (102)면의 X -ray e -rocking분석올 통하여 확인하 였다 .. n-GaN의 경우 SiH4양올 3 - 13 sccm으로 증가시킴에 따라 n -type 도명농 도가 선형적으로 증가하였고, 1017/c며 범위 내로 도평이 된 경우 상온에서 300 e마 N Ns 이상의 high mobility를 얻올 수 있었다 .. PL 관측 결과로부터 Si 도핑으로 인 하여 GaN bandedge emission이 강화됨을 알 수 있었다 .. InGaN 박막의 경우 성 장온도를 낮춤에 따라서 m의 양을 증가시킬 수 있었다. 또한 유량비(TMIn I T TMGa)가 1에 가까운 경 우에서도 온도를 635 "C 정도로 낮훈 경우 410 nm정도에 서 PL bandedge peak올 얻을 수 있었으며, 이 때의 반치폭은 50 meV정도의 낮 은 값을 보였다. 반치폭은 50 meV정도의 낮 은 값을 보였다.

• 한국환경과학회지
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• 제32권4호
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• pp.277-284
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• 2023

Seventy Pipistrellus abramus samples were caught to analyze their sexual dimorphism and mophological characteristics. The mean HB and FA were 50.86 mm and 34.93 mm, respectively, based on external measurements and skull shape. The length of the TL, Hfcu, and Tra were approximately 70%, 55.6%, and 38% of the HB, Tib, and E, respectively. Both the lambdoid crest and the sagittal crest were well developed and the H.BC was approximately 84% of the W.BC. P2 was inside the toothrow and metacone of canine was clearly visible. According to the analysis of sexual dimorphism, the following characteristics were different in between males and females: WS, C-M³, C-C, M³-M³, LOM, LUC, and i-m³. The WS, C-M³, C-C, M³-M³, LOM, and i-m³ were bigger in females than males, whereas the LUC was bigger in males.

• Biomolecules & Therapeutics
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• 제6권1호
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• pp.45-49
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• 1998

The pharmacokinetic properties and antiinflammatory activity of 3% ketoprofen lotion (ID-lotion), formulated with poloxamer 407, were evaluated using rats. For the pharmacokinetic study, the lotion, at the dose of 4.5 mg/kg, was applied on the dorsal skin of rats and the drug concentration in plasma was determined using an HPLC method. As references, ketoprofen suspended in saline was administered orally, and E-lotion, which is a 3% ketoprofen lotion in the Japanese market was applied transdermally. Following the transdermal application of ID-lotion and E-lotion, $C_{max}$ were 316 $\pm$22.3 ng/ml and 163 $\pm$ 12.2 ng/ml, respectively, at the same Tma of 2 hours postdose, while $C_{max}$ and $T_{max}$ after oral administration of the drug were 1,030$\pm$89.1 ng/ml and 0.25 hours, respectively. Relative bioavailabilities of ID-lotion and I-lotion were 69.3% and 34.2%, respectively. The antiinflammatory activity of the two 3% ketoprofen lotions was evaluated with carrageeneninduced edema method after 50 mg of the lotions was applied on the paw of rats. ID-lotion showed 67.6% inhibition of the edema formation, while I-lotion showed 34.\\\\`r%. The calculated ED5o after transdermal application of ID-lotion was 2.5 mg/kg, while that after oral administration was 7.0 mg/kg. Based on these results, the relative equiponderal availability of ID-lotion was 296% compared to the oral administration of ketoprofen.n.n.n.

• 한국미생물·생명공학회지
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• 제23권4호
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• pp.446-453
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• 1995

$\alpha $-Arabinofuranosidase was produced by E. coli HB101 haboring the recombinant plasmid pKMG11 which contained the arfI gene of Bacillus stearothermophilus. The maximum production of the enzyme was observed when E. coli HB101 cells were grown at 37$\circ$C for 20 hours in the medium containing 0.5% arabinose, 1.0% tryptone, 0.5% yeast extract, and 1% NaCl. The $\ALPHA $-arabinofuranosidase produced was purified to homogeneity using a combination of 20-50% ammonium sulfate precipitation, DEAE-Sepharose CL-6B ion exchange column chromatography and Sepharose 6B-100 gel filtration. The purified enzyme was most active at 55$\circ$C and pH 6.5. The K$_{m}$ and V$_{max}$ values of the enzyme on $\rho $-nitrophenyl-$\alpha $-arabinofuranoside was determined to be 2.99 mM and 0.43 $\mu $mole/min (319.74 $\mu $mole/min/mg), respectively. The pI value was 4.5. The molecular weight of the native protein was estimated to be 289 kDa. The SDS-polyacrylamide gel clectrophoresis analysis suggested that the functional protein was a trimer of the 108 kDa identical subunits. The N-terminal amino acid sequence of the a-arabinofuranosidase was identified as X-Ser-Thr-Ala-Pro-Arg( \ulcorner )-Ala-Thr-Met-Val-Ile-Asp-X-Ala-Phe.

• E2M - 전기 전자와 첨단 소재
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• 제8권3호
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• pp.324-331
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• 1995

0.36[wt%l $SiO_{2}$ and 0.1[wt%] $H_{3}$B $O_{3}$ were added to strontium ferrite magnets of the magnetoplumbite phase SrO.5.7F $e_{2}$ $O_{3}$ to hinder grain growth and accelerate sintering, respectively. This experiment was carried out to investigate effect of particle size distribution as a function of milling time(20, 30, 40, 50, 60, 70 hours) on the magnetic properties of SrO.5.7F $e_{2}$ $O_{3}$ ferrite magnet. The B-H curve, density and the degree of orientation were measured. And the microstructure of ferrite magnets was examined with a SEM. The optimal conditions and properties of the typical sample are the following : The milling time was 60 hours. Magnetic and physical properties are $B_{r}$=4, 000[G], $_{b}$ $H_{c}$=3, 330[Oe], (BH)max=3.786[MGOe], $_{I}$ $H_{c}$=3, 525[Oe], density=5.0063[g/c $m^{3}$] and orientation factor f=0.813.0.813.3.3.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2010년도 춘계학술대회 초록집
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• pp.125.2-125.2
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• 2010

In this paper, both theoretical and experimental investigations have been performed to examine the effects of key operating parameters on the cell performance of a DMFCs (i.e., methanol feed concentration and operating temperature). For experiment, the membrane electrode assemblies (MEAs) were prepared using a conventional MEA fabrication method based on a catalyst coated electrode (CCE) and tested under various cell temperatures and methanol feed concentrations. The polarization curve measurements were conducted using in-house-made $25cm^2$ MEAs. The voltage-current density data were collected under three different cell temperatures ($50^{\circ}C$, $60^{\circ}C$, and $70^{\circ}C$) and four different methanol feed concentrations (1 M, 2 M, 3 M, and 4 M). The experimental data indicate that the measured I-V curves are significantly altered, depending on these conditions. On the other hand, previously developed one-dimensional, two-phase DMFC model is simulated under the same operating conditions used in the experiments. The model predictions compare well with the experimental data over a wide range of these operating conditions, which demonstrates the validity and accuracy of the present DMFC model. Furthermore, both simulation and experimental results exhibit the strong influences of methanol and water crossover rates through the membrane on DMFC performance and I-V curve characteristics.

• 한국구조물진단유지관리공학회 논문집
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• 제25권1호
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• pp.67-74
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• 2021

본 논문에서는 노후화된 PSC I형 교량을 대상으로 철근부식에 대한 구조적 안전성을 평가하였다. 대상 PSC I형 교량은 실제 구조물을 참고하여 철근을 배근하고 해석 시 콘크리트의 파괴와 철근의 항복을 고려하였다. 한국시설안전공단 정밀안전진단의 교량 평가 기준을 참고하여 철근노출면적률과 철근부식률로 구분하여 총 32가지의 철근부식 시나리오를 구성하였다. 철근노출은 교량의 바닥판 하부 인장철근이 콘크리트 피복 탈락에 의해 노출된 것으로 가정하였다. 각 시나리오별 해석 결과, PSC I형 교량의 안전율과 내하율은 철근노출면적률과 철근부식률이 증가함에 따라 감소하였다. 철근부식률이 50% 이상일 경우는 모든 철근노출면적률에 대해서 안전성등급을 세밀하게 분석할 필요가 있었으며, 철근부식률 57%이상인 경우는 철근노출면적률에 관계없이 모두 E등급으로 산정되었다. 철근노출면적률 2%에 대해서 상관도 분석을 실시한 결과,철근부식률이 약 55.8% 까지는 A등급, 56.9% 까지는 C등급, 58.5% 까지는 D등급, 58.5% 이상인 경우 E등급으로 평가되었다. 본 연구를 통해 노후화된 교량에 대한 철근부식의 정량적인 구조적 안전성 평가가 필요할 것으로 판단된다.

• Computers and Concrete
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• 제33권5호
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• pp.605-619
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• 2024

The increase of reclaimed asphalt pavement (RAP) content in recycled asphalt concrete (RAC) is accompanied by the degradation of low-temperature cracking resistance, which has become an obstacle to the development of RAC. This paper aims to reveal the meso-scale mechanisms of the low-temperature fracture behavior of RAC and provide a theoretical basis for the economical recycling of RAP. For this purpose, micromechanical heterogeneous peridynamic model of RAC was established and validated by comparing three-point bending (TPB) test results against corresponding numerical simulation results of RAC with 50% RAP content. Furthermore, the models with different aggregate shapes (i.e., average aggregates circularity (${\bar{C_r}}=1.00$, 0.75, and 0.50) and RAP content (i.e., 0%, 15%, 30%, 50%, 75%, and 100%) were constructed to investigate the effect of aggregate shape and RAP content on the low-temperature cracking resistance. The results show that peridynamic models can accurately simulate the low-temperature fracture behavior of RAC, with only 2.9% and 13.9% differences from the TPB test in flexural strength and failure strain, respectively. On the meso-scale, the damage in the RAC is mainly controlled by horizontal tensile stress and the stress concentration appears in the interface transition zone (ITZ). Aggregate shape has a significant effect on the low-temperature fracture resistance, i.e., higher aggregate circularity leads to better low-temperature performance. The large number of microcracks generated during the damage evolution process for the peridynamic model with circular aggregates contributes to slowing down the fracture, whereas the severe stress concentration at the corners leads to the fracture of the aggregates with low circularity under lower stress levels. The effect of RAP content below 30% or above 50% is not significant, but a substantial reduction (16.9% in flexural strength and 16.4% in failure strain) is observed between the RAP content of 30% and 50%. This reduction is mainly attributed to the fact that the damage in the ITZ region transfers significantly to the aggregates, especially the RAP aggregates, when the RAP content ranges from 30% to 50%.

• 한국초전도ㆍ저온공학회논문지
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• 제7권1호
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• pp.5-8
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• 2005

MOD Process using metal acetates or trifluoroacetates has been considered to be a strong candidate for a low cost fabrication process for coated conductor with high $J_e$. Recently, an economical MOI) process has been developed for coated conductor with high $J_c$ using low cost starting materials such as YBCO powders. YBCO thin films prepared by single coating on LAO substrate with this modified oxide-precursor solution gives transport $I_c$ of 100A/cm-w and the $J_c$ value of $2.9MA/cm^{2}$ (77K, Self-field). The YBCO coated conductor prepared by single coating with $CeO_2/IBAD-YSZ/SS$ tape gives transport $I_c$ of 50A/cm-w in 2cm. Characterization with XRD, SEM shows that the YBCO layers were epitaxially grown and exhibit well-developed dense micro-structures. This newly developed oxide-precursor based MOD process will provide a low cost route to coated conductor with high $J_c$.