• Journal of the Korean Society for Library and Information Science
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• v.57 no.1
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• pp.183-211
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• 2023

As a private school and a library in the Enlightenment Period of Korea, Woo-Hyun Seoru(友弦書樓) was established between 1904 - March 1905 by Lee, Dong Jin who had a will and provided a economic support for it and his son Lee, Il Woo had founded and operated it and it seemed to be closed in 1911. By this time, Woo-Hyun Seoru has been underestimated or ignored in the history of libraries in Korea. This study tried to investigate 8 aspects of Woo-Hyun Seoru as a modern library including the subject and purpose of establishment, the date of establishment, the location and buildings, the collection development and the acquisition methods, the user group and the important users, the library activities, the process of closure, and the moving path of the collections after the closure of Woo-Hyun Seoru. To do this, the articles of newspaper, periodicals, and academic journals, the relating documents and Sung Nam Se Go(城南世稿) written by Dong Jin Lee, Il Woo Lee and their descendants and colleagues were analyzed.

• Analytical Science and Technology
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• v.20 no.4
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• pp.339-346
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• 2007

To search the ninhydrin derivatives that have high chromogenic and fluorogenic properties, molecular holographic quantitative structure property relationship (HQSPR) models on the reactivity between glycine and ninhydrin analogues as latent fingerprint detector were derived and investigated quantitatively. The ${\varepsilon}LUMO$ (e.v.) energy of ninhydrin molecule was an important factor to reactivity of ninhydrin. And, it is suggested that the nucleophilic reaction by orbital-controlled reaction from the frontier molecular orbital (FMO) interaction between glycine and ninhydrin derivatives was more superior than that of electrophilic reaction by charged controlled reaction. The analytical results in atomic contribution maps also shows that the reactivity of ninhydrin was increased by meta-substituents as strong electron withdrawing groups on the benzo ring. Therefore, it is sugested by HQSPR and QSPR model that the 5,6-dinitroninhydrin molecule would increase the reactivity as much as three times as compared to none substituted ninhydrin molecule.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.44-44
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• 2022

우리나라의 경우 강수량의 2/3 정도가 하절기에 집중되는 강우특성상 해마다 여름철 홍수기의 탁수 문제가 다양하게 발생하고 있다. 이상강우와 기상이변에 의한 집중강우가 증가 추세이며, '02년 태풍 루사', '03년 태풍 매미', '06년 에위니아'부터 20년 마이삭, 하이선 까지 장마와 태풍에 의한 유입량이 급증하는 시기 탁수의 유입으로 수중 탁도가 급상승하며 댐 저수지 내 탁수 문제가 발생하였다. 특히 연 평균 물사용량의 대부분을 하천 및 댐 저수지를 이용하는 우리나라의 경우 탁수 문제가 장기화될 경우 댐 하류 해당 지역 농업, 공업, 수생태 등 사회적, 환경적으로 많은 문제를 발생시킨다. 이러한 탁수 예측을 통한 대응을 위해 탁수 모델링에 대한 연구가 활발히 진행되고 있다. 탁수를 모델링을 위해서는 유량, 수온, SS 데이터가 필요하다. 이를 위해 국가측정망에서 하천 및 댐 저수지 내 SS를 측정하여 탁수를 측정 하고 있으나 설비가 미흡하여 데이터 해상도가 낮다는 한계점이 있으며 주요 댐 저수지 내에서는 수자원공사에서 관리하는 자동 측정기기를 활용하여 높은 데이터 해상도를 유지 하고 있으나 댐 별, 기상 조건에 따라 미측정 기간이 존재한다. 탁도를 측정을 위한 센서로는 Optical Backscatter Sensor(OBS), YSI 등이 있으며 SS를 측정하기 위한 센서는 레이저부유사측정기(LISST: Laser In-Situ Scattering and Transmissometry) 등의 장비를 이용하고 있다. 하지만 이런 첨단 센서의 경우 또한 수중 고정하여 측정하기에는 장비의 안정성 등의 이유로 한계가 있음에 따라 취득된 유량, 수온, SS, 탁도 데이터를 기반으로 분석을 통해 미측정 기간에 대한 보간이 필요하다. 본 연구에서는 국가 측정망 데이터 및 강우시 유량에 따른 탁수 유입의 증가와 탁수 유입에 따른 항목별 측정 데이터를 기반으로 유량, 수온, SS 미측정 기간을 보간하여 입력자료로 탁수를 모의하여 분석하고자 하였다.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2022.09a
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• pp.38-38
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• 2022

동해안 지역에서 발생되는 대형 산불의 원인은 건조주의보, 영동지역에서 불어오는 강한 바람, 소나무의 단순림, 임도 유무와 상태 등을 들고 있다. 조사 대상지인 삼척 검봉산 일대는 기존 소나무가 우점하는 곳으로 2001년 복원을 위해 소나무, 곰솔, 굴참나무 등을 조림하였고, 일부는 자연복원을 하였다. 복원 이후 21년 지난 현재 삼척 검봉산 일대 산불피해 복원지역의 식생은 크게 굴참나무-소나무군락, 소나무신갈나무군락, 곰솔-소나무군락으로 나누어지는 것으로 나타났다. 산불피해지 식생 회복은 굴참나무, 소나무, 곰솔 등 조림으로 현재 식생은 산불 발생 이전의 임상으로 회복되고 있다. 특히, 산불의 유형 중 지표화 피해지역은 하층 식생의 피해가 크다. 기존의 소나무는 결실된 종자를 비산하여 치수를 발생시켜 자연복원의 속도를 높이고 굴참나무를 활용한 인공복원은 맹아를 발달시켜 본인의 영역을 확장하는 전략을 지니고 있다. 단, 입지적 환경이 동일하다는 전제 조건에서 숲에서 재생 기작이 진행되는 자연복원보다는 인공복원이 회복시간과 종다양성이 높은 측면에서는 효과적인 것으로 결론을 지을 수 있다. 식생군락을 분류한 결과 굴참나무-소나무군락, 소나무-신갈나무군락, 곰솔소나무군락으로 3개 군락으로 나누어졌다. 인공복원지에 식재한 굴참나무, 소나무, 곰솔은 복원 이후 지속적으로 해당지역의 식생이 우점종으로 자생하고 있는 것으로 나타났으나, 소나무-신갈나무군락의 경우 참나무과 식물인 신갈나무와 굴참나무, 졸참나무가 교목층과 아교목층에 자연유입되고 있어 향후 신갈나무가 우점하는 활엽수림으로 천이 될 것으로 예상된다. 군락의 종다양도지수는 낙엽활엽수가 우점하는 굴참나무-소나무군락이 가장 높게 나타났으며, 침엽수림인 곰솔소나무군락이 가장 낮게 나타났다. 산불피해지 식생은 조림수종에 영향을 크게 받으며, 21년이 지난 현재 산불 이전 임상으로 회복되는 경향을 나타내었다. 향후, 효과적인 복원을 위한 DB구축 및 모니터링자료 마련을 위해 산불피해지에 대한 지속적인 식생조사를 통한 자료구축이 필요하다.

• Molecules and Cells
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• v.46 no.10
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• pp.627-636
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• 2023

Periodontal disease is a chronic inflammatory disease that leads to the gradual destruction of the supporting structures of the teeth including gums, periodontal ligaments, alveolar bone, and root cementum. Recently, interests in alleviating symptoms of periodontitis (PD) using natural compounds is increasing. Avenanthramide-C (Avn-C) is a polyphenol found only in oats. It is known to exhibit various biological properties. To date, the effect of Avn-C on PD pathogenesis has not been confirmed. Therefore, this study aimed to verify the protective effects of Avn-C on periodontal inflammation and subsequent alveolar bone erosion in vitro and in vivo. Upregulated expression of catabolic factors, such as matrix metalloproteinase 1 (MMP1), MMP3, interleukin (IL)-6, IL-8, and COX2 induced by lipopolysaccharide and proinflammatory cytokines, IL-1β, and tumor necrosis factor α (TNF-α), was dramatically decreased by Avn-C treatment in human gingival fibroblasts and periodontal ligament cells. Moreover, alveolar bone erosion in the ligature-induced PD mouse model was ameliorated by intra-gingival injection of Avn-C. Molecular mechanism studies revealed that the inhibitory effects of Avn-C on the upregulation of catabolic factors were mediated via ERK (extracellular signal-regulated kinase) and NF-κB pathway that was activated by IL-1β or p38 MAPK and JNK signaling that was activated by TNF-α, respectively. Based on this study, we recommend that Avn-C may be a new natural compound that can be applied to PD treatment.

• Biomolecules & Therapeutics
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• v.32 no.2
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• pp.249-260
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• 2024

New supplements with preventive effects against skin photodamage are receiving increasing attention. This study evaluated the anti-photoaging effects of salmon nasal cartilage proteoglycan (SPG), acting as a functional material for skin health. We administered SPG to in vitro and in vivo models exposed to ultraviolet B (UVB) radiation and assessed its moisturizing and anti-wrinkle effects on dorsal mouse skin and keratinocytes and dermal fibroblasts cell lines. These results showed that SPG restored the levels of filaggrin, involucrin, and AQP3 in the epidermis of UVB-irradiated dorsal skin and keratinocytes, thereby enhancing the keratinization process and water flow. Additionally, SPG treatment increased the levels of hyaluronan and skin ceramide, the major components of intercellular lipids in the epidermis. Furthermore, SPG treatment significantly increased the levels of collagen and procollagen type 1 by down-regulating matrix metalloproteinase 1, which play a crucial role in skin fibroblasts, in both in vitro and in vivo models. In addition, SPG strongly inhibited mitogen-activated protein kinase (MAPKs) signaling, the including extracellular signal-regulated kinase, c-Jun N-terminal kinase (JNK), and p38. These findings suggest that dietary SPG may be an attractive functional food for preventing UVB-induced photoaging. And this SPG product may provide its best benefit when treating several signs of skin photoaging.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.18 no.4
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• pp.262-270
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• 2008

This study was conducted to measure concentrations of particulate matter ($PM_{10}$, $PM_{2.5}$) and endotoxin in thirty public facilities (7 elderly-care facilities, 4 hypermarkets, 4 university hospitals, 7 child-care facilities, 4 subway stations and 4 bus terminals) from September 2004 to February 2007 in Seoul and Gyeonggi-do province. $PM_{10}$ or $PM_{2.5}$ was measured with glass fiber filter and mini volume air sampler for 6 to 8 hours in indoor and outdoor of the facilities and expressed as ${\mu}g/m^3$. After weighing the filter, endotoxin was analyzed by Limulus Ameobocyte Lysate method ($EU/m^3$). $PM_{10}$ in indoor air was higher (GM and GSD was 78.00 and $1.92\;{\mu}g/m^3$, respectively) than the outdoor air (GM and GSD was 60.70 and $2.23\;{\mu}g/m^3$, respectively, I/O=1.28). All measurements was not exceeded the national maintenance standard. Elderly-care and child-care facilities showed relatively higher concentrations ($83.27\;{\mu}g/m^3$ and $81.75\;{\mu}g/m^3$; I/O=2.01 and 1.19, respectively) than hypermarkets or university hospitals. The highest PM2.5 was seen in child-care facilities ($62.15\;{\mu}g/m^3$, I/O=2.42). The I/O of the endotoxin in the PM10 and the $PM_{2.5}$ was exceeded 1.0 (1.37 and 1.57, respectively). Indoor $PM_{10}$ was affected by user/day and humidity, and endotoxin in the PM10 was affected by temperature. In conclusion, elderly- and child-care facilities are high priority facilities to be improved indoor air quality.

• Journal of Chest Surgery
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• v.27 no.4
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• pp.272-280
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• 1994

Total 400 St.Jude Medical Bileaflet Valves were implanted in 336 pts from January 1983 to June 1993; 64 were aortic, 205 were mitral, 64 were double valve and 3 were tricuspid position. The follow up period extended from 6 months to 10 years[mean 24.3 months]. Male to female ratio was 1:1.7. There were total 27 deaths[cardiac related 20, cardiac non-related 7]. Overall mortality was 2.9%/pt-yr. There were 10 early deaths[3.0%] and 10 late cardiac related deaths [3.0%]. Prosthetic valve related complications occurred in 19 patients[5.7%] and among them, seven died; four died of thromboembolic events, two died of anticoagulants therapy related hemorrhagic complications and one died of bacterial endocarditis. NYHA class improved significantly especially in aortic valve replacement and double valve replacement. In AVR cases, the mean NYHA was 2.8 preoperatively and 1.3 postoperatively. And in DVR cases, 3.3 preoperatively and 2.2 postoperatively. The decision to employ a particular prosthesis was made according to the anticipated or known complications of the valve. The St.Jude Medical Valve retains all the hazards of other mechanical valves, most notably, thromboembolism. But the hemodynamic performance of St.Jude Medical Valve compared most favorably with other substitute valves in many reports. 0ur experience didn`t show any differences compared other authors in terms of valve related complication. So we concluded St. Jude Medical Valve can be primarily considered in the selection of artificial valve except in the patients when the usage of anticoagulant therapy is contraindicated.

• Journal of dental hygiene science
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• v.13 no.3
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• pp.230-237
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• 2013

In this research, the degree of depression and death orientation of the 332 female students majoring in dental hygiene at colleges located in Gyeongsangbuk-do Province were examined and analyzed through a structured self-administered questionnaire from May to July, 2012, for the purpose of improving their mental health. The results are as follows: 1. The degree of depression of the subject students majoring in dental hygiene was shown that 59.9%, 36.8%, 3.0%, and 0.3% of the students were in the normal group, mild depression group, moderate level of depression group, and severe depression group, respectively. 2. The grand mean and the standard deviation of the subjects'death orientation was $2.09{\pm}0.62$ points. 3. The degree of depression of the subjects whose family's economic level was low, whose satisfaction with their family background was low, whose satisfaction level with their major was low, whose school records was low, who frequently thought about death, and who attempted suicide was high in a meaningful way, and death orientation was meaningfully low. In addition, those in the group with the experience of feeling suicidal were proved to have a significantly high degree of depression, and those without the experience of education about death had a low level of death orientation. 4. The degree of depression and death orientation had a positive correlation. When the study results above are combined, follow-up research needs to be conducted so that differentiated programs linked with the care for mental health for the formation of proper attitudes toward depression and death will be established to help students lead a positive life.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2004.11a
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• pp.175-181
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• 2004

A construction project of Incheon 2nd bridge, which is connected between the Incheon Song-Do New Town and the Incheon International Airport in Young-Jong-Do, have been proposed by the private capital in 1999. But the optimal span width in the bridge main span have not been decided in spite of the three investigations into the feasibility of ship's safe transit in this planned bridge. In this paper, we study the optimal main span width according to the traffic volume in the future traffic and the ship maneuverability of maximum size aspect. The result cf this study, Incheon 2nd bridge main span design is required to design two-way traffic scheme and 1,000m span width, which will satisfy the safe transit from the viewpoint of the traffic volume in the future traffic and the ship maneuverability maximum size.