• Journal of applied mathematics & informatics
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• v.39 no.1_2
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• pp.197-214
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• 2021

In this paper, we have studied dynamics of fractional order mathematical model of malaria transmission for two groups of human population say semi-immune and non-immune along with growing stages of mosquito vector. The present fractional order mathematical model is the extension of integer order mathematical model proposed by Ousmane Koutou et al. For this study, Atangana-Baleanu fractional order derivative in Caputo sense has been implemented. In the view of memory effect of fractional derivative, this model has been found more realistic than integer order model of malaria and helps to understand dynamical behaviour of malaria epidemic in depth. We have analysed the proposed model for two precisely defined set of parameters and initial value conditions. The uniqueness and existence of present model has been proved by Lipschitz conditions and fixed point theorem. Generalised Euler method is used to analyse numerical results. It is observed that this model is more dynamic as we have considered all classes of human population and mosquito vector to analyse the dynamics of malaria.

• Proceedings of the Korea Society for Energy Engineering kosee Conference
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• 2000.11a
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• pp.115-120
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• 2000

The analysis of flux distribution under stead-state in large power reactors with assymetry reactivity insertions requires the use of three-dimensional diffusion calculations. For the purpose, consistently formulated modern nodal methods based on higher order interface techniques have become popular tools for flux distributions in large commercial nuclear reactors. Among the earlier developments, the nodal Green's function method obtains its nodal interface equation from the transverse-integrated integral diffusion equation using a finite-medium Green's function. In this method, the outgoing current from a node surface is formulated as a response of the incoming currents and the spatially integrated neutron source within the same node. The well-known nodal expansion method is also based on an interface partial current formulation. Nodal methods high-level interface variables, i.e., interface net current and flux, may be more computationally efficient than the nodal Green's function method because they have one fewer unknown per interface. The Analytic Nodal Method(ANM), which can be classified as an interface net current technique and, was faster in solving some standard benchmark problems than the other two methods.(omitted)

• Journal of Embryo Transfer
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• v.23 no.3
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• pp.223-227
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• 2008

The cryopreservation of Hanwoo embryos has become an integral part of assisted reproduction in animal. The objective of this study was to assess the effect of The objectives of this study were: (1) to evaluate the influence of bovine embryo developmental stage on in vitro embryo development after freezing, (2) to study the efficiency compared with conventional freezed embryos at different embryo source. For conventional slow-freezing, day 7 or 8 expanded blastocysts were collected. The standard freezing medium was 1.8 M ethylene glycol (EG). Embryos were equilibrated in 1.8 Methylene glycol(EG) with 0.1 M sucrose in Dulbecco's phosphate-buffered saline (D-PBS) supplemented with 0.5% bovine serum albumin. Embryos were then loaded individually into 0.25 ml-straw and placed directly into cooling chamber of programmable freezer precooled to $-7^{\circ}C$, after 2 min, the straw was seeded, maintained at $-7^{\circ}C$ for 8 min, and then cooled to $-35^{\circ}C$ at $0.3^{\circ}C$/min, plunged and stored in liquid nitrogen for at least 3 days. For thawing, the straw containing embryos were warmed in air for 10 see and exposed to $37^{\circ}C$ water for 20 sec. Straws were then removed from $37^{\circ}C$ water. Rates of blastocyst survive and hatched were evaluated at 12 to 48h post-warming. The re-expansion and hatched rates of morula embryos were significantly lower than those obtained for blastocysts and expansion blastocysts (31.6%, 10.5% vs, 68.9%, 22.2% vs, 73.7%, 53.6%, respectively). No differences in re-expansion rates were found between in vivo and in vitro blastocysts. whereas hatched rates was significantly higher (51.2%) in vivo compared with in vitro embryos (18.6%). in conclusion, demonstrate that conventional freezing can be used successfully in cryopreservation of in vitro and in vivo bovine embryos, and that it might be considered for use in commercial programs and embryo preservation.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.3
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• pp.889-896
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• 2015

Matrix metalloproteinase-2 (MMP2) is an endopeptidase, mainly responsible for degradation of extracellular matrix components, which plays an important role in cancer disease. A single nucleotide polymorphism (SNP) at -1306 disrupts a Sp1-type promoter site. The results from the published studies on the association between MMP2 -1306 C>T polymorphism and cancer risk are contradictory and inconclusive. In the present study, a meta-analysis was therefore performed to evaluate the strength of any association between the MMP2 -1306 C>T polymorphism and risk of cancer. We searched all eligible studies published on association between MMP2 -1306 C>T polymorphism and cancer risk in PubMed (Medline), EMBASE and Google Scholar online web databases until December 2013. Genotype distribution data were collected to calculate the pooled odds ratios (ORs) and 95% confidence intervals (95%CIs) to examine the strength of the association. A total of 8,590 cancer cases and 9,601 controls were included from twenty nine eligible case control studies. Overall pooled analysis suggested significantly reduced risk associated with heterozygous genotype (CT vs CC: OR=0.758, 95%CI=0.637 to 0.902, p=0.002) and dominant model (TT+CT vs CC: OR=0.816, 95%CI=0.678 to 0.982, p=0.032) genetic models. However, allelic (T vs C: OR=0.882, 95%CI=0.738 to 1.055, p=0.169), homozygous (TT vs CC: OR=1.185, 95%CI=0.825 to 1.700, p=0.358) and recessive (TT vs CC+CT: OR=1.268, 95%CI=0.897 to 1.793, p=0.179) models did not show any risk. No evidence of publication bias was detected during the analysis. The results of present meta-analysis suggest that the MMP2 -1306 C>T polymorphism is significantly associated with reduced risk of cancer. However, further studies with consideration of different populations will be required to evaluate this relationship in more detail.

• Development and Reproduction
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• v.20 no.4
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• pp.289-296
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• 2016

This report describes the sex differentiation of the Korean rose bitterling, Rhodeus uyekii, from hatching to 170 days post-hatch (DPH) in relation to total length (TL), body weight (BW), and integral water temperature (IWT). The growth curve of TL from just hatching to 83 DPH was $5.144e^{0.045t}$ ($R^2=0.961$; t, time), and that of BW was $2.398e^{0.086t}$ ($R^2=0.725$). Primordial germ cells (PGCs) were observed at 17 DPH (7.9 mm TL, 3.74 mg BW, $374^{\circ}C$ IWT), and thereafter began to protrude into the peritoneal cavity. At 21 DPH ($9.2{\pm}0.14mm$ TL, $4.8{\pm}0.07mg$ BW, $462^{\circ}C$ IWT), some PGCs contained condensed chromatin and oocyte were observed in meiotic prophase. In contrast to the ovaries, which grew gradually after sexual differentiation, testes began multiplying at 25 DPH (10.1 mm TL, 5.42 mg BW, $550^{\circ}C$ IWT), when testicular differentiation was first identified, and multiplied continuously thereafter. At 33 DPH (11.2 mm TL, 10.5 mg BW, $726^{\circ}C$ IWT), the developing testes contained spermatogonia that exhibited mitotic activity. No spermatocyte or sperm cell was observed until 83 DPH (18.9 TL, 48.2 mg BW, $1,826^{\circ}C$ IWT). At 170 DPH (32.5 mm TL, 270.1 mg BW, $3,740^{\circ}C$ IWT), which was the end point of this study, the mature ovaries showed germinal vesicle breakdown, while the mature testes contained observable spermatocytes and sperm cells. These results allow us to identify the sex differentiation type of the Korean rose bitterling as differentiated gonochoristic.

• Journal of the Korean Magnetics Society
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• v.2 no.1
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• pp.1-7
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• 1992

Deuterium was injected into melt-spun ribbons of ${\alpha}-Fe_{90}Zr_{10}$ using the electrolytic hydrogenation method, and the magnetic properties of these ${\alpha}-D_{x}Fe_{90}Zr_{10}$ ribbons were studied. By comparing these results with those of ${\alpha}-H_{x}Fe_{91}Zr_{9}$, the effects of phonons to magnetic properties were investigated. The Curie temperature $T_{c}$, and the spontaneous magnetizations of the $D_{47}Fe_{90}Zr_{10}$ and the $Fe_{90}Zr_{10}$ were studied using the Mbssbauer spectroscopy. From these investigations, it was found that the Curie temperature of $D_{x}Fe_{90}Zr_{10}$ was 75K higher than that of $Fe_{90}Zr_{10}$. It was believed that this indicated the importance of local deformation to the amorphous magnetism. Also by comparing the spontaneous magnetizations of $D_{47}Fe_{90}Zr_{10}$ with those of $Fe_{90}Zr_{10}$ as a function of temperature, it was found that the deuterium injection reduced the fluctuation of exchange integral.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.7
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• pp.645-652
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• 2015

In this study, a method for determining Ramberg-Osgood constants for leak-before-break evaluation was investigated. The Ramberg-Osgood constants were calculated for SA312, TP316, and SA-508 Gr.1a in an operating temperature of $316^{\circ}C$. Incremental plasticity, using stress-strain data obtained from experiment, and deformation plasticity, using the Ramberg-Osgood constants, were considered in a finite element analysis. Using incremental plasticity and deformation plasticity, J-integrals and crack opening displacement values were calculated and compared. By comparing the results of incremental plasticity and deformation plasticity, a suitable method for determining Ramberg-Osgood constants for leak-before-break evaluation was confirmed.

• Corrosion Science and Technology
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• v.3 no.2
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• pp.59-66
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• 2004

In construction of new ships and large steel bridges in Korea, pre-construction primers (PCP), also known as shop primer, are routinely used and retained as an integral part of the protective coating system. Retention of PCP's can significantly reduce building schedule and cost. Retaining PCP through the so-called "sweep blasting" procedure eliminates or minimizes the necessity of a second blast operation, thus shortening overall schedule as well as reducing labor cost and hazardous waste disposal cost. This study evaluates the feasibility of retaining PCP as the part of primer for high performance protective coating systems applied to ships' hull, bottom and ballast tanks. Upon proving that the retention of the PCP is a viable option, the process of coating application can he improved significantly in terms of cost and working schedule of new ships and large steel bridges. Results indicate that use of the PCP via sweeping blasting in conjunction with standard high performance protective coating systems does not degrade the overall performance of the coating systems. At the same time, it is also highly recommended that the secondary surface preparation should consist of grit blasting of weld burnt and other damaged areas to SSPC SP-IO grade (Sa 2.5 Gr.), Near White Blast Cleaning with proper application and attention to detail.

• Journal of Microbiology and Biotechnology
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• v.27 no.12
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• pp.2190-2198
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• 2017

Thermoactinomyces sp. strain YT06 was isolated from poultry compost and observed to degrade integral chicken feathers completely at $60^{\circ}C$, resulting in the formation of 3.24 mg/ml of free amino acids from 50 ml of culture containing 10 g/l chicken feathers. Strain YT06 could grow and secrete keratinase using feather as the only carbon and nitrogen sources without other supplement, but complementation of 10 g/l sucrose and 4 g/l $NaNO_3$ increased the production of the keratinolytic enzyme. The maximum protease activity obtained was 110 U/ml and for keratinase was 42 U/ml. The keratinase maintained active status over a broad pH (pH 8-11) and temperature ($60-75^{\circ}C$). It was inhibited by serine protease inhibitors and most metal ions; however, it could be stimulated by $Mn^{2+}$ and the surfactant Tween-20. A reductive agent (${\beta}$-mercaptoethanol) was observed to cleave the disulfide bond of keratin and improve the access of the enzyme to the keratinaceous substrate. Zymogram analysis showed that strain YT06 primarily secreted keratinase with a molecular mass of approximately 35 kDa. The active band was assessed by MALDI-TOF mass spectrometry and was observed to be completely identical to an alkaline serine protease from Thermoactinomyces sp. Gus2-1. Thermoactinomyces sp. strain YT06 shows great potential as a novel candidate in enzymatic processing of hard-to-degrade proteins into high-value products, such as keratinous wastes.

• Journal of the Korean Society of Costume
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• v.65 no.6
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• pp.1-14
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• 2015

This study is aims to study the background of how the shape of the wooden shoes developed and worn by Koreans and Japanese in the ancient times by sorting and examining the types and shapes. Relevant bibliography, which are mainly related to the excavated wooden shoes from 3 B.C.E to C.E. 8., were used as research materials. The formation of wooden shoes required easy access to raw materials -which is trees- for production. According to the analysis, both Korea and Japan made the flat wooden shoes using cuboid wood. Both countries bore a hole on a specific location to distinguish the right foot and left foot, however the style of the heel was different in the two countries. The slip-on(Undu-hyeong) wooden shoes were also common in both countries. The slip-on had no-heels and was made by digging-out a piece of the cuboid wood. Some slip-ons made by the Japanese had furrows on the bottom, and they were known to make different types of the slip-on wooden shoes depending on the purpose. Observation of the wearing methods show that commonality can be found between the wooden shoes of Korea and Japan, and this indicates that cultural exchanges between the Silla/Baekje and Japan took place from the 4th to the 6th century. Also, the flat wooden shoes in Japan developed rapidly, as the shoes became an integral part of its life and culture, which was closely tied to agriculture. Eventually, due to the difference in climate and life-style, the slip-ons became the primary type of wooden shoes in Korea, while the flats became the main type of wooden shoes in Japan. It is, however, clear that as the relationship between the two countries became closer, the cultural exchanges regarding the wooden shoes were considerable.