• Title/Summary/Keyword: $BL_{13}$

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Morphological Changes in Adipose and Liver Tissues by 17$\beta$-estradiol in Female Ovariectomized C57BL/6J Mice

  • Jeong, Sun-Hyo;Choi, Hyung-Kyu;Yoon, Mi-Chung
    • Biomedical Science Letters
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    • v.13 no.2
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    • pp.99-104
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    • 2007
  • To determine whether 17$\beta$-estradiol induces the morphological changes in adipose and liver tissues, we measured the effects of 17$\beta$-estradiol on adipose tissue mass, adipocyte histology and hepatic lipid accumulation in female ovariectomized (OVX) C57BL/6J mice. Compared to vehicle-treated control mice, 17$\beta$-estradiol-treated mice decreased adipose tissue mass and the size of adipocytes, and concomitantly increased the number of adipocytes in a dose-dependent manner. In addition, the administration of 17$\beta$-estradiol resulted in reduced hepatic lipid accumulation in a dose-dependent manner. These results suggest that estrogen may regulate adipocyte development and lipid metabolism in female OVX C57BL/6J mice.

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Anti-inflammatory Activities of Cinanamomum burmanni Bl

  • Khatib, Alfi;Kim, Mi-Yeon;Chung, Shin-Kyo
    • Food Science and Biotechnology
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    • v.14 no.2
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    • pp.223-227
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    • 2005
  • Anti-inflammatory assay was conducted on 20 kinds of traditional Indonesian medicinal herbs using soybean lipoxygenase (SLO) and hyaluronidase (HAse). Cinnamomun burmanni Bl showed highest anti-inflammatory activity. Ethyl acetate fraction from methanol extract of C. burmanni Bl bark showing high SLO inhibitory activity was isolated using silica gel-60 column chromatography. Two compounds were isolated and purified through preparative HPLC. Through analyses of UV, $^1H-NMR$, $^{13}C-NMR$, EI-MS and $FAB^+-MS$, compounds 1 and 2 were identified as coumarin and 2-hydroxy cinnamaldehyde, respectively, among which 2-hydroxy cinnamaldehyde showed SLO inhibitory activity of $IC_{50}\;=\;60\;{\mu}M$. Both compounds did not exhibit HAse inhibitory activity.

Light Curve of BL Cam using KASINICS

  • Han, Jang-Hui;Son, Jeong-Ju;Seong, Hyeon-Il;Jeon, Yeong-Beom;Angeloni, Rodolfo;Grijs, Richardde
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.2
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    • pp.149.1-149.1
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    • 2011
  • 보현산 천문대의 근적외선 카메라시스템인 KASINICS(KASI Near Infrared Camera System)를 사용하여 다주기 변광성 BL Cam을 관측하였다. BL Cam(${\alpha}=03^h47^m19^s$, ${\delta}=+63^{\circ}22'7"$[J2000.0], V=13.10, ${\Delta}V$=0.33mag)은 광학적 쌍성으로 SX Pheoenics 변광성 중 하나이며 0.03 - 0.08day의 짧은 주기를 갖는 다주기 변광성으로 알려져 있다. 대상 천체의 적외선 관측을 위하여 한국천문연구원에서 개발한 지상 망원경용 근적외선 카메라 시스템 KASINICS를 사용해 J, H, Ks filter로 시계열 관측을 하였다. 대상 천체의 가시광 파장대에서의 관측 자료와 적외선 파장대에서의 관측 자료를 비교 분석함으로써 천체의 외곽층에서 발생하는 상호작용에 대해 알아볼 수 있다.

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A Study on the TCAD Simulation to Predict the Latchup Immunity of High Energy Ion Implanted CMOS Twin Well Structures (고 에너지 이온 주입된 CMOS 쌍 우물 구조의 레치업 면역성 예측을 위한 TCAD 모의실험 연구)

  • 송한정;김종민;곽계달
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.13 no.2
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    • pp.106-113
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    • 2000
  • This study describes how a properly calibrated simulation method could be used to investigate the latchup immunity characteristics among the various high energy ion implanted CMOS twin well (retro-grade/BILLI/BL) structures. To obtain the accurate quantitative simulation analysis of retrograde well, a global tuning procedure and a set of grid specifications for simulation accuracy and computational efficiency are carried out. The latchup characteristics of BILLI and BL structures are well predicted by applying a calibrated simulation method for retrograde well. By exploring the potential contour, current flow lines, and electron/hole current densities at the holding condition, we have observed that the holding voltage of BL structure is more sensitive to the well design rule (p+to well edge space /n +to well edge space) than to the retrograde well itself.

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A Review of Case Reports on the Application of Acupuncture as a Treatment for Fracture since 2013 (골절에 침 치료를 적용한 2013년 이후 증례보고 문헌고찰)

  • Paik, Seung-Won;Nam, Kyeong-Ho;Choi, Seung-Kwan;Lee, Jung-Han;Han, Yun-Hee
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.4
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    • pp.49-63
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    • 2021
  • Objectives This study aimed to investigate the trend in treating fracture with acupuncture and to evaluate the quality of case reports. Methods All case reports of fractures treated with acupuncture were extracted from four Korean web databases. We classified these studies by five fracture sites and investigated frequently used meridian and acupoint, outcome measurements, treatment period. And we assessed the quality of the case reports by the STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) guidelines. Results A total of 33 case reports were included. The outcome measurements were divided into six categories, and the outcome measurements used in more than three studies showed improvement in patient symptoms. The mainly used meridians for each fracture site were as follows: chest and abdomen (GB, LR, CV), back (BL, GB), upper limb (LI, TE), lower Limb (GB, ST, BL, SP). The most commonly used acupoints for each fracture site were as follows: chest and abdomen (Ashi points, GB24, GB25, GB26, LR13, LR14, CV16, CV17, CV18, CV19), back (BL23, BL24, BL25, BL26, BL40, BL51, BL52, BL60, GB34), upper limb (LI4, LI10, LI11, TE3), lower limb (GB34, GB40). According to the STRICTA guidelines, more than 54.54% of the reports were found to be 'not reported' or 'not sufficient' in the following categories: 'response sought', 'description of participating acupuncturist', and 'number of needle insertions per subject per session'. Conclusions The meridians and acupuncture points frequently used for acupuncture treatment of fractures were near the fracture site. Future clinical studies involving acupuncture must be reported in accordance with the STRICTA guidelines to improve transparency and uniformity.

Amino Acid Concentrations in the Blastocoelic Fluid of In Vitro-Produced Bovine Blastocysts (체외생산된 소 배반포강 내의 아미노산 농도)

  • Jung, Y.G.;Wei, H.;Yoon, J.T.;Fukui, Y.
    • Journal of Embryo Transfer
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    • v.13 no.3
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    • pp.251-259
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    • 1998
  • Concentrations of free amino acids in the BF of IVP bovine BL and HBL were examined in this study. The embryos derived from IVF oocytes were cultured in a SOFM containing BSA, EAA and NEAA. BF was aspirated from BL (180 h of age after insemination) and HBL (216 h of age after insemination), and introduced into drops of SOFM (30$\mu$l/drop) containing PVA through micromanipulation. The medium containing BF was then subjected to measurement of 20 amino acids by an automatic amino acid analyzer. The concentrations of isoleucine, leucine and methionine were higher (p〈0.05) in the BF from HBL than from BL, and no difference was found in aspartate or glutamate concentrations between BL and HBL, while threonine, alanine (p〈0.01) and the rest of the amino acids (p〈0.001) were significantly higher in the BF from HBL than from BL. Cystine was not found in either BL or HBL. A high concentration of glutamine was found in the BF from both BL and HBL, although it was not added to the culture medium. These results indicate that bovine BF contains several EAA (methionine in BL and isoleucine, leucine and methionine in HBL) and NEAA (alanine, glutamate, glycine, proline, serine and aspartate in BL, and glutamate and aspartate in HBL), and there is significant differences in the amino acid concentration in the BF between BL and HBL derived by WP.

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The Effects of BU Herbal Acupuncture on Low Back Pain of Sprain (좌섬요통에 대한 BU 약침의 효과)

  • Seo, Bo-Myung;Lee, Yoon-Kyung;Choi, Sung-Hoon;Kim, Kyung-Woon;Yoon, Jong-Seok;Lim, Seong-Chul;Jung, Tae-Young;Han, Sang-Won;Seo, Jung-Chul
    • Journal of Pharmacopuncture
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    • v.8 no.2
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    • pp.5-10
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    • 2005
  • Objectives : This study was designed to estimate the effects of BU herbal acupuncture theraphy on low back pain of sprain patients by using Visual Analogue Scale(VAS) and pressure algometer. Methods : 13 volunteers were applied to BU herbal acupuncture stimulation on the BL23, BL24, BL25 and BL26 acupoints. The degree of improvement of low back pain of sprain was evaluated by VAS and pain pressure threshold(at the points of BL23 and BL24 before treatment, before 3rd treatment(after herbal acupuncture). Results : In VAS scores, there were significant differences between before and after herbal acupuncture stimulation. But there was no significant difference between before and after herbal acupuncture stimulation in pain threshold. Conclusions : The effectiveness of BU herbal acupuncture theraphy on low back pain of sprain was shown through VAS and pressure algometer. These imply that BU herbal acupuncture theraphy may be useful for low back pain of sprain. Further study is needed about BU herbal acupuncture.

Analysis of Meridians Energy change by Cupping Stimulation (부항자극에 대한 체표 경락.경혈의 생체에너지 변화 분석)

  • Kim, Soo-Byeong;Lee, Na-Ra;Kim, Young-Dae;Lim, Jong-Hyeon;Song, Gil-Soo;Jung, Byung-Jo;Lee, Yong-Heum
    • Korean Journal of Acupuncture
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    • v.27 no.4
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    • pp.49-57
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    • 2010
  • Objectives : The aim of this study is evaluation for significance of skin meridian-acupoints energy measurement system, and is verification of principle to measure the bio-ion charge on acupoints. Methods : To check a correlation between the MEP(Meridian Energy Potential) and bio-electric charge condition, ten acupoints(left/right BL meridian : BL13, BL15, BL18, BL20, BL23) were chosen. Based on basic theory concerning the upward trend of the bio-electric charge by cupping therapy, we measured MEP change before and after 600mmHg(80kPa) Negative pressure stimulation using cupping. Results : We could identify the correlation between MEP and the condition of bio-electric charge in acupoints. Also, we checked the balance or imbalance of left/right the MEP and unusual cases. Conclusions : We confirmed significance of proposed principle and meridian energy measurement system.

Ensiled Banana Wastes with Molasses or Whey for Lactating Buffaloes during Early Lactation

  • Khattab, H.M.;Kholif, A.M.;EI-Alamy, H.A.;Salem, F.A.;EI-Shewy, A.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.5
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    • pp.619-624
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    • 2000
  • Low-quality roughages [banana wastes (B), wheat straw (WS) and dried broiler litter (BL)] were ensiled using either sweet whey (W) or diluted molasses (M) as rehydration media to study their effects on milk yield, milk composition and some parameters of blood plasma. The feeding trial involved 25 lactating buffaloes in five groups (five animals each). Buffaloes as control animals received diets of concentrate feed mixture, rice straw and wastelages (70:30:00). In the other 4 treatments, the wastelages replaced 50% of rice straw in the control diets. The wastelages were BL:B:M(3:2:10) (T1), BL:WS:M (3:2:10) (T2), BL:B:W (3:2:10) (T3) and BL:WS:W (3:2:10) (T4) on a fresh matter basis, during the 1st 17 weeks of lactation period. Results indicated that feeding lactating buffaloes on wastelages resulted in slightly higher (p>0.05) milk yield, 4% fat-corrected-milk yield and feed efficiency, and slightly lowered (p>0.05) contents of milk total solids, fat and protein. Wastelages, especially BL-B-M, increased (p<0.05) milk non-protein-nitrogen and ash contents and plasma urea, GOT and GPT. The results demonstrate that banana plant wastes with some additives in silage form may be good untraditional roughage for lactating buffaloes without any adverse effect on milk production.

Estimation of bioluminescence intensity of the dinoflagellates Noctiluca scintillans, Polykrikos kofoidii, and Alexandrium mediterraneum populations in Korean waters using cell abundance and water temperature

  • Sang Ah Park;Hae Jin Jeong;Jin Hee Ok;Hee Chang Kang;Ji Hyun You;Se Hee Eom;Yeong Du Yoo;Moo Joon Lee
    • ALGAE
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    • v.39 no.1
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    • pp.1-16
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    • 2024
  • Many dinoflagellates produce bioluminescence. To estimate the intensity of bioluminescence produced by populations of the heterotrophic dinoflagellates Noctiluca scintillans and Polykrikos kofoidii and autotrophic dinoflagellate Alexandrium mediterraneum in Korean waters, we measured cellular bioluminescence intensity as a function of water temperature and calculated population bioluminescence intensity with cell abundances and water temperature. The mean 200-second-integrated bioluminescence intensity per cell (BLcell) of N. scintillans satiated with the chlorophyte Dunaliella salina decreased continuously with increasing water temperature from 5 to 25℃. However, the BLcell of P. kofoidii satiated with the mixotrophic dinoflagellate Alexandrium minutum continuously increased from 5 to 15℃ but decreased at temperatures exceeding this (to 30℃). Similarly, the BLcell of A. mediterraneum continuously increased from 10 to 20℃ but decreased between 20 and 30℃. The difference between highest and lowest BLcell of N. scintillans, P. kofoidii, and A. mediterraneum at the tested water temperatures was 3.5, 11.8, and 21.0 times, respectively, indicating that water temperature clearly affected BLcell. The highest estimated population bioluminescence intensity (BLpopul) of N. scintillans in Korean waters in 1998-2022 was 4.22 × 1013 relative light unit per liter (RLU L-1), which was 1,850 and 554,000 times greater than that of P. kofoidii and A. mediterraneum, respectively. This indicates that N. scintillans populations produced much brighter bioluminescence in Korean waters than the populations of P. kofoidii or A. mediterraneum.