• Title/Summary/Keyword: $A{\delta}$ and C fiber

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Reliability of Quantitative Sensory Testing Using Current Perception Thresholds in the Mandibular Nerve Area (하악신경영역에서 전류인지역치를 이용한 정량적 감각신경 검사의 재현성 조사)

  • Choi, Hee-Hun;Kim, Mee-Eun;Kim, Ki-Suk
    • Journal of Oral Medicine and Pain
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    • v.36 no.2
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    • pp.131-137
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    • 2011
  • Current Perception Threshold (CPT) using Neurometer($Neurometer^{(R)}$ CPT/C) is thought as one of easy and noninvasive QST(qunatitative sensory testing) tools for A${\beta}$, A${\delta}$ and C fibers within a relatively short time. However, conflicts about its reliability still exist. This study aimed to evaluate the reliability of CPTs evaluation and find a way to increase its reliability. Two examiners separately tested CPTs at each side of the mandibluar nerve areas for ten healthy male adults (average age of 22.4 years) three times with an intervals of a week during three weeks. Mean CPTs were compared between the right and left sides of the mandibular nerve area and between the three examinations on the each side. While CPTs at 2000 Hz(A${\beta}$ fiber) showed statistically significant side differences in all three examinations (p<0.05), significant side difference was found in only one examination at 250 Hz(A${\delta}$ fiber) and no difference at 5 Hz(C fiber). Comparing CPTs on the each side of the mandibular nerve area, all examinations at all sensory nerve fibers showed the least CPTs at the 1st examinations. CPTs at 250 Hz(A${\delta}$ fiber) and 5 Hz(C fiber) were significantly different between the first and the following examinations (p<0.05) and there was no significant difference between 2nd and 3rd examinations. The results of this study indicated that CPTs at 250 Hz(A${\delta}$ fiber) and 5 Hz(C fiber) are reliable but CPTs at 2000 Hz(A${\beta}$ fiber) is not appropriate for evaluation of side differences in the mandibular nerve area. In addition, it is suggested that repeated examination be helpful to increase reliability of the CPT evaluation.

EFFECT OF POTASSIUM ION ON INTRADENTAL NERVE ACITIVITY (칼륨이온이 치수내 신경활동에 미치는 영향)

  • Son, Ho-Hyun;Park, Soo-Joung;Lee, Kwang-Won
    • Restorative Dentistry and Endodontics
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    • v.17 no.1
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    • pp.1-9
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    • 1992
  • The intradental nerve activity was recorded from single pulp nerve unit dissected from the inferior alveolar nerve in canine teeth of anesthetized cats. The effects of various test solutions on intradental nerve activity evoked by 4M NaCl applied to the deep dentinal cavities were investigated. 1. Total 15 single pulp nerve units were recorded. Of these 9 were Mi - fibers and 6 were C -fibers. The mean conduction velocity and electrical threshold of $A{\delta}$ - fiber were $6.3{\pm}3.7m/sec$, $1.2{\pm}0.7V$ and those of C - fiber were $1.0{\pm}0.2m/sec$, $2.3{\pm}1.3V$, respectively. The response to cold stimuli of $A{\delta}$ - fiber began immediately and that of C - fiber began after a latency. 2. When applied to deep dentinal cavity, 4M NaCl induced irregular bursts of action potential in 4 $A{\delta}$ - fibers and 3 C - fibers, which continued until the solution was washed away. 3. In the $A{\delta}$ - fiber, histamine failed to induce any nerve acitivity and did not produce an increase in intradental nerve activity evoked by 4M NaCl. However following the application of 1M KCl, the response to 4M NaCl was eliminated. 4. In the C - fiber, histamine generated some nerve activity and produced a significant increase in intradental nerve activity evoked by 4M NaCl, but 5M $CaCl_2$ did not abolish this enhandced response.

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Fiber Bragg Grating Temperature Sensor by the Wavelength Tuning Using the Temperature Dependence of VCSEL (빅셀(VCSEL)의 온도 의존성을 이용한 파장 가변 형 광섬유 격자 온도센서)

  • Lee, Chung-Ki;Kim, Sung-Moon
    • Korean Journal of Optics and Photonics
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    • v.29 no.6
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    • pp.241-246
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    • 2018
  • In this paper, a low-cost optical temperature sensor is implemented, using a fiber Bragg grating (FBG) as the temperature probe and a low-cost VCSEL with temperature-dependent output wavelength as the light source. To analyze the wavelength of the reflected light from the FBG, an interrogation was applied using a method of referring to the internal temperature according to the output wavelength of the VCSEL. When the temperature of the VCSEL was adjusted from 14 to $52.2^{\circ}C$, the output wavelength varied from 1519.90 to 1524.25 nm. The degree of wavelength tuning according to temperature was $0.114nm/^{\circ}C$. The variable wavelength repeatability error according to temperature was ${\pm}0.003nm$, and the temperature measurement error was ${\pm}0.18^{\circ}C$. As a result of measuring the temperatures from 22.3 to $194.2^{\circ}C$, the value of the internal temperature change of the light source according to the applied temperature ${\Delta}T$ was $0.146^{\circ}C/{\Delta}T$, the change in reflected wavelength of the temperature probe according to applied temperature ${\Delta}T$ was measured at $16.64pm/^{\circ}C$. and the temperature measurement error of the sensor was ${\pm}1^{\circ}C$.

Dyeing of Wool at Low Temperature - focusing on solubility parameter$(\delta)$ - (양모의 저온 염색(1) - 용해도 파라미터$(\delta)$를 중심으로 -)

  • 도성국
    • Textile Coloration and Finishing
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    • v.15 no.6
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    • pp.55-62
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    • 2003
  • Wool fabrics were dyed with the aqueous solution of C. I. Red Acid 114 mixed with methanol dissolving three kinds of barely water soluble ketones, acetophenone, 2-pentanone, and 3-pentanone. The steric hinderance and the orientation of the bigger hydrophobic part of the solvated dye molecules to the fiber slowed down the dying rate, however, loosening the wool molecule, say a little swelling, disaggeregating the dye molecules, and attaining the higher dye concentration on the fiber surface by the added solvents increased the amount of dye on the fabric. The higher concentration or/and the higher dyeing temperature helped loosen fiber molecules and made it easier for the solvated dye molecules to penetrate into the inside of the fiber. Acetophenone, the most influential solvent used, showed that the ability to loosen fiber molecules was the most important of all the three positive solvent actions mentioned above. The considered mechanism provided before reflected the fact that the dye uptake on the fabric dyed with the solvents included, except for 0.034M and 0.051M of acetophenone, was even lower than that without any solvents at $50^\circ{C}$, but all the solvents added to the dye bath increased the dye uptake on the fiber at $70^\circ{C}$.

CHANGES IN INTRADENTAL NERVE ACTIVITY FOLLOWING LOCAL APPLICATION OF CGRP, SP AND ELECTRICAL STIMULI IN CATS (CGRP, SP의 국소도포와 전기자국에 의한 고양이 치수신경활동의 변화)

  • Kim, Mi-Ja;Son, Ho-Hyun
    • Restorative Dentistry and Endodontics
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    • v.20 no.2
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    • pp.527-537
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    • 1995
  • The effect of calcitonin gene-related peptide (CGRP), substance P (SP) and electrical stimulation of the tooth on the intradental nerve activtiy (INA) was investigated in anesthetized cats. The INA was recorded from single pulp nerve units dissected from the inferior alveolar nerve under stereomicroscope. The INA elicited by 3 minute application of 4M NaCl in deep dentinal cavity was compared before and after stimulation at 10 minute intervals. The magnitude of INA was calculated as the total number of nerve impulses produced in given period, and the changes of INA are expressed as % of control INA. The results obtained were as follows. 1. 16 single pulp nerve units were classified as 14 $A{\delta}$-fibers (3.4~19.4m/sec) and 2-fibers (1.5~1.7m/sec) according to the conduction velocity. 2. 4M NaCl evoked an irregular bursts of spikes which continued until washing out. Isotonic saline did not affect INA to subsequent applications of the hypertonic NaCl solution (P>0.05). 3. Local application of CGRP ($200{\mu}g$/ml) in deep dentinal cavity reduced the INA induced by 4M NaCl in $A{\delta}$-fiber units (P<0.01) and some units of those responded to CGRP during application. 4. Local application of SP ($100{\mu}g$/ml) in deep dentinal cavity reduced the INA induced by 4M NaCl in AS-fiber units (p<0.05), but increased the INA in C-fiber unit coincided with large reduction of the INA of $A{\delta}$-fiber units. 5. Monopolar electrical stimulation applied to the crown at intensities high enough to excite C-fibers (12V, 5ms, 10Hz, 10~30min) decreased the INA in $A{\delta}$-fiber units (P<0.01) and systemic pretreatment with phenoxybenzamine (3mg/kg, i.v.) enhanced this inhibitory effect (P<0.01). On the contrary, electrical stimulation increased the INA in C-fiber unit.

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Fabrication and Property of Ba0.5Sr0.5Co0.8Fe0.2O3-δ Hollow Fiber Membranes (Ba0.5Sr0.5Co0.8Fe0.2O3-δ 중공사 분리막의 제조 및 물성)

  • Jeon, Sung Il;Park, Jung Hoon;Kim, Jong Pyo;Sim, Woo Jong;Lee, Yong Taek
    • Korean Chemical Engineering Research
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    • v.50 no.1
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    • pp.1-5
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    • 2012
  • $Ba_{0.5}Sr_{0.5}Co_{0.8}Fe_{0.2}O_{3-{\delta}}$ hollow fiber with o.d. 1.02 mm and i.d. 0.437 mm were fabricated by a phase-inversion spinning technique.The starting $Ba_{0.5}Sr_{0.5}Co_{0.8}Fe_{0.2}O_{3-{\delta}}$ precursor was synthesized by the polymerized complex method and then calcined at $900^{\circ}C$. As-prepared powder was dispersed in a polymer solution, and extruded as form of hollow fiber through a spinneret. Finallydense $Ba_{0.5}Sr_{0.5}Co_{0.8}Fe_{0.2}O_{3-{\delta}}$ hollow fiber membrane was obtained by sintering for 2 h at $1,080^{\circ}C$ for the application of oxygen separation. In addition, despite a very thin membrane with 0.58 mm, the BSCF hollow fiber membrane possessed a proper mechanical strength of 602.5 MPa.

The Role of Somatostatin in Nociceptive Processing of the Spinal Cord in Anesthetized Cats

  • Jung, Sung-Jun;Park, Joo-Min;Lee, Jun-Ho;Lee, Ji-Hye;Kim, Sang-Jeong;Kim, Jun
    • The Korean Journal of Physiology and Pharmacology
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    • v.3 no.4
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    • pp.365-373
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    • 1999
  • Somatostatin (SOM) is one of the major neuropeptides in dorsal root ganglion cells, but its role in spinal nociceptive process has not been well known. In present study we aimed to investigate the effect of SOM on the response of dorsal horn neurons to the various types of peripheral nociceptive stimuli in anesthetized cats. Using carbon-filament microelectrode, the single cell activities of wide dynamic range neurons were recorded from the lumbosacral enlargement after noxious mechanical (squeeze), thermal (radiant heat lamp) and cold (dry ice) stimulation to the receptive field. Sciatic nerve was stimulated electrically to evoke $A\;{\delta}-$ and C-nociceptive responses. SOM analogue, octreotide $(10\;{\mu}g/kg),$ was applied intravenously and the results were compared with those of morphine (2 mg/kg, MOR). Systemic SOM decreased the cellular responses to the noxious heat and the mechanical stimulation, but increased those to the cold stimulation. In the responses to the electric stimuli of sciatic nerve, $A\;{\delta}-nociceptive$ response was increased by SOM, while C-nociceptive response was decreased. On the other hand, MOR inhibited the dorsal horn cell responses to all the noxious stimuli. From the above results, it is concluded that SOM suppresses the transmission of nociceptive heat and mechanical stimuli, especially via C-fiber, while it facilitates those of nociceptive cold stimuli via $A\;{\delta}-fiber$.

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Effects of Somatostatin on the Responses of Rostrally Projecting Spinal Dorsal Horn Neurons to Noxious Stimuli in Cats

  • Jung, Sung-Jun;Jo, Su-Hyun;Lee, Sang-Hyuck;Oh, Eun-Hui;Kim, Min-Seok;Nam, Woo-Dong;Oh, Seog-Bae
    • The Korean Journal of Physiology and Pharmacology
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    • v.12 no.5
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    • pp.253-258
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    • 2008
  • Somatostatin (SOM) is a widely distributed peptide in the central nervous system and exerts a variety of hormonal and neural actions. Although SOM is assumed to play an important role in spinal nociceptive processing, its exact function remains unclear. In fact, earlier pharmacological studies have provided results that support either a facilitatory or inhibitory role for SOM in nociception. In the current study, the effects of SOM were investigated using anesthetized cats. Specifically, the responses of rostrally projecting spinal dorsal horn neurons (RPSDH neurons) to different kinds of noxious stimuli (i.e., heat, mechanical and cold stimuli) and to the $A{\delta}$ -and C-fiber activation of the sciatic nerve were studied. Iontophoretically applied SOM suppressed the responses of RPSDH neurons to noxious heat and mechanical stimuli as well as to C-fiber activation. Conversely, it enhanced these responses to noxious cold stimulus and $A{\delta}$-fiber activation. In addition, SOM suppressed glutamate-evoked activities of RPSDH neurons. The effects of SOM were blocked by the SOM receptor antagonist cyclo-SOM. These findings suggest that SOM has a dual effect on the activities of RPSDH neurons; that is, facilitation and inhibition, depending on the modality of pain signaled through them and its action site.

Effect of Several Solvents on Low Temperature Wool Dyeing (몇 가지 용매가 양모의 저온염색에 미치는 영향)

  • Dho, Seong-Kook
    • Fashion & Textile Research Journal
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    • v.11 no.4
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    • pp.672-677
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    • 2009
  • To reduce the dependence of wool dyeing on the temperature several solvents with different properties and structures were added to the dye bath of C. I. Acid Yellow 42. Nearly the same total solubility parameters(${\delta}_t$) of solvents as those of wool fiber and hydrophobic part of the dyestuff were needed to increase disaggregation of dye molecules, loosening the wool fiber and wickabilty of dyeing solution; besides, the large surface tension(${\gamma}$) value of the solvents and the well balanced values of the three-component Hansen solubility parameters such as dispersion(${\delta}_d$), polar(${\delta}_p$), and hydrogen(${\delta}_h$) bonding parameters were required. Among the added solvents dimethyl phthalate(DMP) and acetophenone(AP) were satisfied with these conditions and worked the most successfully in the low temperature wool dyeing. Their effectiveness proven by the dyeing rate and the activation energy ($E_a$) of the dyeing was in the order of DMP > AP > DBE > CH > M >NONE. In conclusion the total solubility parameters(${\delta}_t$), the three-component Hansen parameters and the surface tension(${\gamma}$) of DMP and AP could be the guidelines to select suitable solvents for low temperature wool dyeing.

Fiber Identification via the TISS and DELTA Systems (TISS system 및 DELTA system에 의한 섬유식별)

  • 전수경
    • Journal of the Korea Furniture Society
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    • v.10 no.1
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    • pp.1-12
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    • 1999
  • Of the vast number of plant taxa in the world, the wood is one of the most useful resources. It is important to identify the fibers of wood and pulp for the plant taxonomy and for the uses, but we do not have enough information on them, on them, especially for the computerizd data. The fiber identification is one of the difficult tasks. In addition to the plant taxonomy and the fiber-using industries, such identification is also important in many other fields, including education. document examiners, etc. For these purpose, the fibers should be exactly distinguished. The TISS system I have programed to identify various woods would also be useful in the identification of fibers by the genus and species in the features of unknown samples and in searching the features of a species based on its scientific name. Such searching programs are being developed in many other countries with a view to searching for the species name by using the features of the cells of the woody materials. With the survey of all the available literature, the features of the fibers of 124 species both of softwood and hardwood were examined under the electron and optical microscopies. Each species were coded and carded by the feature, and the databases were built. The microscopic were inputted into a personal computer program called and by a slide film scanner. The new computer program called TISS 2 was developed using C computer language. Korean language fonts were added to the TISS 2. The TISS 2 can be in adding and searching a image of fiber features both of a known fiber and an unknown fiber. The databases were corded for the DELTA system with was developed by Dallwitz and Paine in Australia, 1986.

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