• 한국음향학회지
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• 제32권2호
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• pp.124-130
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• 2013

수중음향통신 시스템의 성능은 신호의 다중경로 전달 과정에 의해 발생하는 지연 확산 현상 때문에 인접심벌 간 간섭(ISI)에 영향을 받는다. 인접 심벌 간 간섭을 제거하기 위해 등화기가 사용되어진다. 본 논문에서는 한국 연근해에서 수집된 실측 데이터를 이용하여 채널 부호화 기법과 등화기가 결합하여 동작하는 터보 등화기를 갖는 수중음향통신 시스템의 성능을 검증하였다. 그 결과 터보 등화기를 이용하여 반복 복호를 하였을 때는, 1회 반복 시 BER(Bit Error Rate) $10^{-4}$을 기준으로 반복이 없는 등화기를 사용하였을 때 보다 1.5 dB 성능이 향상되었다. 또한 반복이 2~3회인 경우 약 3.5 dB 성능이 향상되었으나, 3회 이상 반복하였을 때는 더 이상 성능이 향상되지 않았다.

• 대한인간공학회지
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• 제32권4호
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• pp.345-353
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• 2013

Objective: This research measured physiological and psychological effects of Vibroacoustic stimulation(VA) to scapular and sacrum of supine position on the mattress. Background: When vibroacoustic stimulation applies to human body, it has a positive influence on physiological and psychological effects by stimulating the organs, tissues and cells of whole body. Method: This experiment was conducted to 10 normal males in two conditions: no stimulation and vibroacoustic stimulation. No stimulation experiment was executed as a supine position for 30 minutes without any vibrational stimulus, while vibroacoustic stimulation was transmitted by the vibrational speaker, which uses 40Hz frequency. Subjects had a laser Doppler flowmeter probe in scapular, sacrum, and also had 8 channel electroencephalogram(EEG) measurement sensor in the scalp. Blood pressure and skin temperature were measured in two conditions with an underlying posture for 30 minutes. Additionally, blood flow rate and EEG were measured before and after for two minutes on two conditions. Results: According to the vibroacoustic stimulation, blood flow rate and skin temperature were increased, while blood pressure was decreased. When using vibroacoustic stimulation compared to no stimulation, blood flow rate went approximately two times higher, and skin temperature also higher 3~4 times. Furthermore, the relative alpha power of brain wave was significantly increased when we applied to vibroacoustic stimulation. Conclusion: This experiment tested the VAT embedded in mattress in two conditions. According to this experiment, VAT decreases blood pressure, improves not only a physiological effect on blood flow rate as well as skin temperature, but also psychological functions by increasing relative alpha power. Application: The results of the publishing trend analysis might help physiological and psychological effects of vibroacoustic stimulation.

• Biomolecules & Therapeutics
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• 제8권1호
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• pp.13-21
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• 2000

The present study was designed to investigate the effect f quinidine on catecholamine (CA) secretion evoked by ACh, high $K^{+}$, DMPP, McN-A343, cyclopiazonic acid and Bay-K-8644 from the isolated perfused rat adrenal gland and to establish the mechanism of its action. The perfusion of quinidine (15-150 $\mu$M) into an adrenal vein for 60 min produced relatively dose- and time-dependent inhibition in CA secretion evoked by ACh (5.32$\times$10$^{-3}$ M), high $K^{+}$ (5.6$\times$10$^{-2}$ M), DMPP (10$^{-4}$ M for 2 min), McN-A-343 (10$^{-4}$ M for 2 min), cyclopiazonic acid (10$^{-5}$ M for 4 min) and Bay-K-8644 (10$^{-5}$ M for 4 min). Furthermore, in adrenal glands pre-loaded with quinine (5$\times$10$^{-5}$ M), CA secretory responses evoked by veratridine (10$^{-4}$ M) was time-dependently inhibited. Also, in the presence of lidocaine (10$^{-4}$ M), which is also known to be a sodium channel blocker, CA secretory responses evoked by ACh, high potassium, DMPP, McN-A-343, Bay-K-8644 and cyclo-piazonic acid were also greatly reduced in similar fashion to that of quinidine-treatment. Taken together, these results suggest that quinidine causes greatly the inhibition of CA secretion evoked by stimulation of cholinergic (both nicotinic and muscarinic) receptors as well as by membrane depolarization, indicating strongly that this effect may be mediated by inhibiting influx of extracellular calcium and release in intracellular calcium in the rat adrenomedullary chromaffin cells. Furthermore, these findings indicate strongly that this inhibitory action of quinidine appears to be associated to the blocking action of sodium channels at least in CA secretion from the rat adrenal gland.and.

• Archives of Pharmacal Research
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• 제24권3호
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• pp.240-248
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• 2001

The present study was attempted to investigate the effect of quinine on secretion of catecholamines (CA) etroked by cholinergic stimulation and membrane depolarization from the isolated perfused rat adrenal gland. The perfusion of quinine (15-150${\mu}$M) into an adrenal vein for 60 min produced dose- and time-dependent inhibition in CA secretion evoked by ACh ($5.32{\times}10^{-3}M$), high $K^{+}5.6{\times}10^{-2}M$, DMPP ($10^{-4}M$ for 2 min), McN-A-343 ($10^{-4}M$ for 2 min), cyclopiazonic acid ($10^{-5}$ for 4 min) and Bay-K-8644 ($10^{-5}$ M for 4 min). Also, under the presence of pinacidil ($10^{-4}$ M), which is also known to be a selective potassium channel activator, CA secretory responses evoked by ACh, high potassium, DMPP McN-A-343, Bay-K-8644 and cyclopiazonic acid were also greatly reduced. When preloaded along with quinine ($5{\times}10^{-5}M$) and glibenclamide ($10^{-6}$ M), a specific blocker of ATP-regulated potassium channels, CA secretory responses evoked by ACh, high potassium, DMPP McN-A-343, Bay-K-8644 and cyclopiazonic acid were recovered as compared to those of quinine-treatment only. taken together, these results demonstrate that quinine inhibits CA secretion evoked by stimulation of cholinergic (both nicotinic and muscarinic) receptors as well as by membrane depolarization through inhibiting influx of extracellular calcium and release in intracellular calcium in the rat adrenmodullary chromaffin cells. These findings suggest that activation of potassium channels may be involved at least in inhibitory action of quinine on CA secretion from the rat adrenal gland.

• Investigative Magnetic Resonance Imaging
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• 제21권2호
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• pp.65-70
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• 2017

Purpose: To optimize the saturation time and maximizing the pH-weighted difference between the normal and ischemic brain regions, on 3-tesla amide proton transfer (APT) imaging using an in vivo rat model. Materials and Methods: Three male Wistar rats underwent middle cerebral artery occlusion, and were examined in a 3-tesla magnetic resonance imaging (MRI) scanner. APT imaging acquisition was performed with 3-dimensional turbo spin-echo imaging, using a 32-channel head coil and 2-channel parallel radiofrequency transmission. An off-resonance radiofrequency pulse was applied with a Sinc-Gauss pulse at a $B_{1,rms}$ amplitude of $1.2{\mu}T$ using a 2-channel parallel transmission. Saturation times of 3, 4, or 5 s were tested. The APT effect was quantified using the magnetization-transfer-ratio asymmetry at 3.5 ppm with respect to the water resonance (APT-weighted signal), and compared with the normal and ischemic regions. The result was then applied to an acute stroke patient to evaluate feasibility. Results: Visual detection of ischemic regions was achieved with the 3-, 4-, and 5-s protocols. Among the different saturation times at $1.2{\mu}T$ power, 4 s showed the maximum difference between the ischemic and normal regions (-0.95%, P = 0.029). The APTw signal difference for 3 and 5 s was -0.9% and -0.7%, respectively. The 4-s saturation time protocol also successfully depicted the pH-weighted differences in an acute stroke patient. Conclusion: For 3-tesla turbo spin-echo APT imaging, the maximal pH-weighted difference achieved when using the $1.2{\mu}T$ power, was with the 4 s saturation time. This protocol will be helpful to depict pH-weighted difference in stroke patients in clinical settings.

• 대한기계학회논문집B
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• 제25권11호
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• pp.1640-1649
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• 2001

The present study investigates the effects of various rib arrangements on heat/mass transfer in the cooling passage of gas turbine blades. A complex flow structure occurs in the cooling passage with rib turbulators which promote heat transfer on the wall. It is important to increase not only the heat transfer rates but also the uniformity of heat transfer in the cooling passage. A numerical computation is performed using a commercial code to calculate the flow structures and experiments are conducted to measure heat/mass transfer coefficients using a naphthalene sublimation technique. A square channel (50 mm $\times$ 50 mm) with rectangular ribs (4 mm $\times$ 5 mm) is used fur the stationary duct test. The experiments focus on the effects of rib arrangements and gap positions in the discrete ribs on the heat/mass transfer on the duct wall. The rib angle of attack is 60°and the rib-to-rib pitch is 32 mm, that is 8 times of the rib height. With the inclined rib angle of attack (60°), the parallel rib arrangements make a pair of counter rotating secondary flows in the cross section, but the cross rib arrangements make a single large secondary flow including a small secondary vortex. These secondary flow patterns affect significantly the heat/mass transfer on the ribbed wall. The heat/mass transfer in the parallel arrangements is 1.5 ∼2 times higher than that in the cross arrangements. However, the shifted rib arrangements change little the heat/mass transfer from the inline rib arrangements. The gap position in the discrete rib affects significantly the heat/mass transfer because a strong flow acceleration occurs locally through the gap.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2001년도 추계학술대회 및 정기총회
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• pp.95-95
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• 2001

Ciinidipine (FRC-8635) is a newly synthesized novel DHP type of organic Ca$\_$2＋/channel blockers that have been developed so far in Japan (Yoshimoto et al., 1991 : Hosono et at., 1992). It also has a blocking action on L-type voltage-dependent Ca$\^$2＋/channel (VDCCs) in the rabbit basilar artery (Oike et al., 1990) and a slow-onset and long-lasting hypotensive action in clinical and experimental studies (Ikeda et al., 1992 ; Tominaga et al., 1997). Recent electrophysiological data indicate that cilnidipine might be a dual-channel antagonist for peripheral neuronal N-type and vascular L-type Ca$\^$2＋/channels (Oike et al., 1990 ; Fujii et al., 1997; Uneyama et at., 1997). However, little is known about the involvement of N-type VDCCs in contributing to the muscarinic receptor-mediated CA secretion. Therefore, the present study was attempted to investigate the effect of cilinidipine on secretion of catecholamines (CA) evoked by ACh, high K$\^$＋/, DMPP and McN-A-343 from the isolated perfused rat adrenal gland. Cilnidipine (1-10 ${\mu}$M) perfused into an adrenal vein for 60 min produced dose- and time-dependent inhibition in CA secretory responses evoked by ACh (5.32${\times}$10$\^$-3/M), DMPP (10$\^$-4/ M for 2 min) and McN-A-343 (10$\^$-4/ M for 2 min). However, lower dose of lobeline did not affect CA secretion by high K$\^$＋/(5.6${\times}$10$\^$-2/ M), higher dose of it reduced greatly CA secretion of high K$\^$＋/. Cilnidipine itself did also fail to affect basal catecholamine output. Furthermore, in adrenal glands loaded with cilnidipine (10 ${\mu}$M), CA secretory response evoked by Bay-K-8644 (10 ${\mu}$M), an activator of L-type Ca$\^$2＋/channels was markedly inhibited while CA secretion by cyclopiazonic acid (10 ${\mu}$M), an inhibitor of cytoplasmic Ca$\^$2＋/-ATPase was no affected. Moreover, $\omega$-conotoxin GVIA (1 ${\mu}$M), given into the adrenal gland for 60 min, also inhibited time-dependently CA secretory responses evoked by ACh and high K$\^$＋/.

• JSTS:Journal of Semiconductor Technology and Science
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• 제16권3호
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• pp.339-345
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• 2016

This paper presents a two-stage power amplifier MMIC using a $0.4{\mu}m$ GaN-HEMT process. The two-stage structure provides high gain and compact circuit size using an integrated inter-stage matching network. The size and loss of the inter-stage matching network can be reduced by including bond wires as part of the matching network. The two-stage power amplifier MMIC was fabricated with a chip size of $2.0{\times}1.9mm^2$ and was mounted on a $4{\times}4$ QFN carrier for evaluation. Using a downlink LTE signal with a PAPR of 6.5 dB and a channel bandwidth of 10 MHz for the 2.6 GHz band, the power amplifier MMIC exhibited a gain of 30 dB, a drain efficiency of 32%, and an ACLR of -31.4 dBc at an average output power of 36 dBm. Using two power amplifier MMICs for the carrier and peaking amplifiers, a Doherty power amplifier was designed and implemented. At a 6 dB back-off output power level of 39 dBm, a gain of 24.7 dB and a drain efficiency of 43.5% were achieved.

• 천문학회보
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• 제36권2호
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• pp.110.1-110.1
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• 2011

오리온 A 분자운은 별탄생이 활발하게 일어나는 영역이다. 때문에 분자운 연구를 통해서 별탄생을 연구하기에는 최적의 곳이다. 특기할 것은 Orion A에는 필라멘트 구조가 있다는 점이다. 필라멘트는 전형적으로는 길이 4.8pc, 너비 1.4 pc 로 제시되었다(Nagahama et al. 1998). 많은 미지의 조건들 가운데 필라멘트 구조는 별탄생에 대한 새로운 조명을 던져주는 데, 가령 분자운이 수축, 분열하며 작은 덩어리를 만드는 과정에 이런 기다란 구조가 별탄생에 어떤 과정에서 나타나며 이것이 별탄생이 어떤 효과를 발생하는지 연구되어야 하는 문제들이다. 대덕전파안테나의 1분의 분해능(Channel resolution 63 KHz/ Band Width 25 MHz) 의 12CO, 13CO(J=1-0) 분자선 관측으로 필라멘트를 이전 연구보다 자세하게 관측하여 이것 안에 있을 것으로 보이는 substructure들 연구하고자 한다. 관측영역은 적경: 5h 32m ~ 5h 37m, 적위: $-5^{\circ}$ 14' ~ $-5^{\circ}$ 37'으로 ($1^{\circ}{\times}1^{\circ}$) 영역을 관측하였다. 그 결과 필라멘트구조를 확인할 수 있었으며 약 0.7pc,약 $1000\;M_{\odot}$의 덩어리들이 이전관측에서 보여진 X자형태가 아니라 일자형태로 분포되어있는 것을 알 수 있었다. 관측된 최소덩어리는 star cluster mass이고 stellar size 의 덩어리는 별탄생 과정 이후 소멸된 것으로 보인다. 관측으로 확인된 덩어리들의 물리적인 성질과 분포를 깊이 연구해 보고자 한다. 향후 Orion A 전체를 추가로 관측하고자 한다.

• 한국진공학회지
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• 제5권1호
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• pp.25-32
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• 1996

An ERD-TOF system is constructed for the nondestructive depth profiling of light elements in thin films in the range of several thousand angstroms. The particles, recoiled by 10 $MeV^{35}Cl$ projectiles, were detected by a Time-Of-Flight spectrometer composed of a MCP (Micro Channel Plate) and a SSB (Silicon Surface Barrier) detector. A two parameter data acquisition system composed of two PC's was constructed for registering simultaneous time and energy signals. A $Si_3N_4$/poly-Si/$SiO_2$/Si sample was anlayzed and the result is compared with RBS. The detection limit, maximum probable depth and depth resolution for light elements in silicon are about $4\times10^{14}atoms/\textrm{cm}^2$, 5, 000$\AA$ and 100$\AA$, respectively.