• 제목/요약/키워드: $4^{th}$ Generation

검색결과 476건 처리시간 0.023초

IL-4 Derived from Non-T Cells Induces Basophil- and IL-3-independent Th2 Immune Responses

  • Kim, Sohee;Karasuyama, Hajime;Lopez, Angel F.;Ouyang, Wenjun;Li, Xiaoxia;Gros, Graham Le;Min, Booki
    • IMMUNE NETWORK
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    • 제13권6호
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    • pp.249-256
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    • 2013
  • How Th2 immunity develops in vivo remains obscure. Basophils have been considered key innate cells producing IL-4, a cytokine essential for Th2 immunity. Increasing evidence suggests that basophils are dispensable for the initiation of Th2 immunity. In this study, we revisited the role of basophils in Th2 immune responses induced by various types of adjuvants. Mice deficient in IL-3 or IL-3 receptor, in which basophil lymph node recruitment is completely abolished, fully developed wild type level Th2 CD4 T cell responses in response to parasite antigen or papain immunization. Similar finding was also observed in mice where basophils are inducibly ablated. Interestingly, IL-4-derived from non-T cells appeared to be critical for the generation of IL-4-producing CD4 T cells. Other Th2 promoting factors including IL-25 and thymic stromal lymphopoietin (TSLP) were dispensable. Therefore, our results suggest that IL-3- and basophil-independent in vivo Th2 immunity develops with the help of non-T cell-derived IL-4, offering an additional mechanism by which Th2 type immune responses arise in vivo.

트림 곡면상에서 사각형 요소망의 자동 생성 (Automatic Generation of Quadrilateral Meshes on Trimmed Surfaces)

  • 김형일;채수원
    • 한국CDE학회논문집
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    • 제4권2호
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    • pp.153-161
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    • 1999
  • An atomatic mesh generation scheme with unstructured quadrilateral elements on trimmed surfaces has been developed. Trimmed surfaces are often encountered in modeling of structures with complex shapes such as aircrafts, automobile structures, pressure vessels and etc. For unstructured mesh generation with quadrilateral elements, a domain decomposition algorithm employing loop operators has been used. Mesh generation on trimmed surface is performed in three steps. First, trimmed surfaces with holes or cuts are transformed to th largest projection planes in which the meshes are constructed. The constructed meshes are transformed to the u-v parametric plane and then finally to the original 3D surfaces. Th exact locations of holes or cuts in projection planes are determined by the Newton-Raphson method. Sample meshes are constructed to demonstrate the effectiveness of the proposed algorithm.

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Effect of process parameters on the recovery of thorium tetrafluoride prepared by hydrofluorination of thorium oxide, and their optimization

  • Kumar, Raj;Gupta, Sonal;Wajhal, Sourabh;Satpati, S.K.;Sahu, M.L.
    • Nuclear Engineering and Technology
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    • 제54권5호
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    • pp.1560-1569
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    • 2022
  • Liquid fueled molten salt reactors (MSRs) have seen renewed interest because of their inherent safety features, higher thermal efficiency and potential for efficient thorium utilisation for power generation. Thorium fluoride is one of the salts used in liquid fueled MSRs employing Th-U cycle. In the present study, ThF4 was prepared by hydro-fluorination of ThO2 using anhydrous HF gas. Process parameters viz. bed depth, hydrofluorination time and hydrofluorination temperature, were optimized for the preparation of ThF4 in a static bed reactor setup. The products were characterized with X-Ray diffraction and experimental conditions for complete conversion to ThF4 were established which also corroborated with the yield values. Hydrofluorination of ThO2 at 450 ℃ for half an hour at a bed depth of 6 mm gave the best result, with a yield of about 99.36% ThF4. No unconverted oxide or any other impurity was observed. Rietveld refinement was performed on the XRD data of this ThF4, and Chi2 value of 3.54 indicated good agreement between observed and calculated profiles.

원격지에서 모노펄스 레이더의 주파수 위상 교정을 위한 독립된 펄스반복주파수 생성 및 제어 (Independent PRF Generation and Control for Frequency Phase Calibration on Mono-pulse Radar at a Remote Location)

  • 양재원;유승오;윤재혁;이동주
    • 한국군사과학기술학회지
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    • 제24권4호
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    • pp.368-373
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    • 2021
  • This paper presents a method of independent pulse repetition frequency(PRF) generation and control for frequency phase calibration on mono-pulse radar at a remote location. In order to generate an independent PRF signal of 320[Hz], pulse width modulation(PWM) of 16-bit timer/counter was applied. For a precision control of PRF signal, 16-bit timer/counter interrupt was changed for each period. Therefore, average frequency of PRF could be controlled by 0.0001[Hz]. To calibrate a frequency phase of mono-pulse radar at a remote location, the proposed PRF generator with a precision control of frequency was used regardless of receiving PRF signal from a radar. For the verification of the proposed PRF generator, theoretical analysis and experimental results are included.

Samsung's $4^{th}$ Generation TFT- LCD Production Line Concept

  • Chang, Won-Kie
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2001년도 International Meeting on Information Display
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    • pp.9-12
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    • 2001
  • With the explosive growth of Note-PC and Desktop monitor market, TFT LCD market confronted a entire supply shortage during 1999. Forecasting a more booming stage for the next several years, many TFT-LCD panel manufacturers continue to expand the capacity of their existing plants and also make an additional investment in building new plants. The new investment is concentrated on the $4^{th}$ generation TFT LCD line in order to improve investment efficiency. The set up of the Samsung's Gen 3.5 line progressed with satisfactorily performance using $600{\times}720mm$ glass size. We have continuously reviewed several issues regarding the glass size for our next Gen. 4 line, which leads to adopt $730{\times}920mm$. Due to the continuous enlargement of a substrate size and following difficulty in transferring cassettes, the next line is expected to be the last line that employs "cassette transfer". The layout of the next line will shift from conventional "concentration-type" to "separation-type" configuration for the purpose of reducing transfer distance as well as transfer time. The details will be discussed in this paper.

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구속 스트레스로 유발된 기억 손상에 대한 맥문동(麥門冬)의 신경보호 효능 (Liriopis Tuber improves stress-induced memorial impairments in rats)

  • 강영건;이태희
    • 대한본초학회지
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    • 제21권2호
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    • pp.63-75
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    • 2006
  • Objectives : We investigated the effects of Liriopis Tuber on the nervous protection. Methods : We measured the reaction behavior with EPM(Elevated Plus Maxe) and MWM(Morris Water Maze) after applying restraint stress to rats. Also, the degrees of AchE generation were measured with immunohistochemical method in the regions of hippocampus, and the degree of TH generation in the regions of VTA and LC, respectively. Results : 1. As the results of measuring how long EPM which reflects anxiety reaction stayed in the open arm, there was the trend which can suppress anxiety reaction in the MMD+stress group(Liriopis Tuber+stress) but no statistical significance. The counting results how many EPM passed between opened and closed arm showed suppression trend against a physical activity in the saline+stress group but there was no statistical significance. 2. According to the result of MWM, the saline+stress group showed the learning retardation which means increased time arriving at goal compared to ti1e normal group at the second and third day of measurement. On the contrary, a learning retardation was significantly decreased in the MMD+stress group. Among the probe trial test a memory loss occurred in the saline+stress group, meanwhile memory ability was notably increased in the saline-stress group. 3. The degree of TH generation was investigated at the VTA and LC respectively after test animals treated with drug. In the saline+stress group, TH-immunoreactive cells were significantly increased, and these stress-induced TH increases were suppressed in the saline+stress group at the VTA region. However, the saline+stress group did not show any significant difference. 4. the degree of AchE generation was investigated at the CA3 of hippocampus. The saline+stress group showed that AchE-immunoreactive cells were significantly decreased. Those stress-induced reductions of AchE cells were meaningfully recovered in the saline+stress group. Although the cells showed recovery trend in the region of CA1 of hippocampus, statistical significance was not observed. Conclusion : The results of our study indicate that Liriopis Tuber can improve spatial memory ability of rats applied a restraint stress. This improvement of the spatial memory ability is considered to have an efficacy of nervous protection that Liriopis Tuber suppresses the generation of AchE in the hippocampus region and enhances the generation of TH in the VTA.

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5세대 이동통신을 위한 MMB 시스템 및 채널 모델 (MMB System and Channel Model for 5th Generation Mobile Communication)

  • 문상미;김보라;사란쉬말리크;김지형;이문식;김대진;황인태
    • 전자공학회논문지
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    • 제51권8호
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    • pp.3-10
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    • 2014
  • 최근 폭증하는 모바일 데이터 트래픽을 수용하기 위하여 밀리미터파 (mmWave)가 큰 관심을 받고 있으며, 4 세대 LTE-A(Long Term Evolution-Advanced) 표준을 기반으로 MMB (Millimeter Mobile Broadband) 시스템의 필요성이 대두되고 있다. 현재 mmWave 통신 채널에 대한 많은 연구가 이루어지고 있으며, MMB 채널 환경에 대한 성능 분석 또한 관심의 대상이다. 본 논문에서는 5세대 이동통신을 위한 MMB 시스템을 설계하고 mmWave의 전파 특성 분석을 통한 채널 모델을 제안한다. 또한 MMB 시스템의 28 GHz 대역에서 MMB 채널 환경에 대한 성능을 비교 분석한다.

발전용 천연가스 일일수요 예측 모형 연구-평일수요를 중심으로

  • 정희엽;박호정
    • 한국태양광발전학회지
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    • 제4권2호
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    • pp.45-53
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    • 2018
  • Natural gas demand for power generation continued to increase until 2013 due to the expansion of large-scale LNG power plants after the black-out of 2011. However, natural gas demand for power generation has decreased sharply due to the increase of nuclear power and coal power generation. But demand for power generation has increased again as energy policies have changed, such as reducing nuclear power and coal power plants, and abnormal high temperatures and cold waves have occurred. If the gas pipeline pressure can be properly maintained by predicting these fluctuations, it can contribute to enhancement of operation efficiency by minimizing the operation time of facilities required for production and supply. In this study, we have developed a regression model with daily power demand and base power generation capacity as explanatory variables considering characteristics by day of week. The model was constructed using data from January 2013 to December 2016, and it was confirmed that the error rate was 4.12% and the error rate in the 90th percentile was below 8.85%.

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