• Title/Summary/Keyword: $3_{10}$-helix

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Far lateral lumbar disc extrusion in a dachshund dog

  • Kim, Jaehwan;Kim, Hyoju;Hwang, Jeongyeon;Eom, Kidong
    • Korean Journal of Veterinary Research
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    • v.59 no.3
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    • pp.165-169
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    • 2019
  • A 6-year-old Dachshund was presented with acute, non-localized pain without neurological dysfunction. Radiography revealed multiple calcifications of intervertebral discs and narrowing of disc space in the thoracolumbar region. Computed tomography and magnetic resonance imaging revealed calcified disc-like material entrapped in the left extraforaminal area and showed a displaced nerve root. Fenestration and removal of the extruded disc material were performed in a routine manner. Histopathological examination showed degenerative disc materials with severe calcification both in the nucleus pulposus and around the annulus fibrosis. Based on imaging, surgical, and histopathologic results, the dog was diagnosed with far lateral lumbar disc extrusion.

TIMELIKE HELICES IN THE SEMI-EUCLIDEAN SPACE E42

  • Aydin, Tuba Agirman;Ayazoglu, Rabil;Kocayigit, Huseyin
    • Honam Mathematical Journal
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    • v.44 no.3
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    • pp.310-324
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    • 2022
  • In this paper, we define timelike curves in R42 and characterize such curves in terms of Frenet frame. Also, we examine the timelike helices of R42, taking into account their curvatures. In addition, we study timelike slant helices, timelike B1-slant helices, timelike B2-slant helices in four dimensional semi-Euclidean space, R42. And then we obtain an approximate solution for the timelike B1 slant helix with Taylor matrix collocation method.

Successful mitral repair in dogs by mitral annuloplasty using Hegar dilator: two case reports

  • Lee, Won-Jong;Kim, Junyoung;Moon, Chang-Hwan;Eom, TaeHeum;Son, DongJu;Lee, Seungmin;Lee, Haebeom;Jeong, Seong-Mok;Kim, Dae-Hyun
    • Journal of Veterinary Science
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    • v.23 no.1
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    • pp.11.1-11.10
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    • 2022
  • Mitral regurgitation (MR) is the most common heart disease in small-breed dogs. Mitral repair, which comprise artificial chorda tendineae implantation and mitral annuloplasty, has become the mainstay of treatment in the veterinary field. We report on two small dogs who underwent mitral repair surgery for MR. A Hegar dilator was used during mitral annuloplasty for accurate and reproducible surgery. In both cases, mitral regurgitant flow almost disappeared after surgery, and clinical signs improved. The treatment regimen was terminated 3 months after the surgery. We concluded that using a Hegar dilator may facilitate mitral valve repair surgery.

Evaluation of Salt Tolerance of Three Foliage Plant as affected by Salinity Concentration in Indoor Ornamental Hydroculture (실내 관상용 물재배에서 염분농도에 따른 3가지 관엽식물의 내염성 평가)

  • Jin Hee Ju;Sun Young Park;Yong Han Yoon
    • Journal of Environmental Science International
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    • v.33 no.4
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    • pp.257-268
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    • 2024
  • This study investigated the growth characteristics of Euonymus japonicus, Hedera helix, and Peperomia puteolata treated with different calcium chloride (CaCl2) concentrations to evaluate salt tolerance limits in hydroculture cultivation. Six concentrations of CaCl2 (0, 1, 2, 5, 10, and 15 g·L-1 referred to as Cont., C1, C2, C5, C10, and C15) were applied to solution - grown plant species. The survival rate, growth index, plant height, plant width, leaf width, leaf length, number of leaves, and relative chlorophyll contents were measured at monthly intervals. Euonymus japonicus, Hedera helix, and Peperomia puteolata survived up to C2, C5, and C10 at each CaCl2 concentration. The Euonymus japonicus was higher in the C1 treatment than in the Cont. for most growth characteristics. Hedera helix had the highest leaf width, leaf length, and number of leaves in the Cont., a significant difference was observed compared with the C1 treatment. The chlorophyll content did not differ significantly between the C5 and Cont. treatments. The leaf width and length of Peperomia puteolata were greater in the C2 and C1 treatments than in the Cont., whereas the number of leaves and chlorophyll content were the highest in C5. Dry weight analysis revealed that Euonymus japonicus, Hedera helix, and Peperomia puteolata were the lowest in the Cont. treatments. Euonymus japonicus was 74% in C15, and Hedera helix, and Peperomia puteolata were analyzed at approximately 37%- 50% and 9%-14%, respectively, regardless of the concentration in the CaCl2 treatment groups. In indoor hydroponic cultivation, the salt tolerance limit concentrations of Euonymus japonicus, Hedera helix, and Peperomia puteolata are 2, 5, and 10 g·L-1, respectively, indicating that hydroculture management techniques should be applied at higher concentrations.

Miniaturization of Inductive Resonator for Implementation of Wireless Power Transfer Technology Using Resonant Inductive Coupling (자기 공진 결합 방식을 이용한 무선 전력 전송기술 구현을 위한 자기 공진기 소형화 설계)

  • Cho, Young Seek;Park, Ji Hye;Nam, Yun Seo;Choi, Seyeong
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.8
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    • pp.1798-1804
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    • 2014
  • A novel inductive resonator for the implementation of wireless power transfer using resonant inductive coupling is presented. The proposed inductive resonator is much smaller than the helix shape resonator suggested by MIT research team but operates the same resonant frequency with comparable wireless power transfer efficiency. The proposed inductive resonator is a spiral shape ($1,696cm^3$), which is 97 % smaller than the helix shape ($59,376cm^3$). The wireless power transfer efficiency is less than 9 % when compared to the helix shape resonator. With the reduce size and comparable efficiency, this novel inductive resonator can be used in practical application of wireless power transfer.

Backbone assignment of HMGB1 A-box and molecular interaction with Hoxc9DBD studied by paramagnetic probe

  • Choi, Ji Woong;Park, Sung Jean
    • Journal of the Korean Magnetic Resonance Society
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    • v.25 no.2
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    • pp.17-23
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    • 2021
  • High mobility group protein B1 (HMGB1) is a highly conserved, non-histone, chromatin associated nuclear protein encoded by HMGB1 gene. HMGB1 proteins may be general co-factors in Hox-mediated transcriptional activation that facilitate the access of Hox proteins to specific DNA targets. It is unclear that the exact binding interface of Hoxc9DBD and HMGB1. To identify the interface and binding affinity of Hoxc9DBD and HMGB1 A-box, the paramagnetic probe, MTSL was used in NMR titration experiment. It is attached to the N-terminal end of HMGB1 A-box by reaction with thiol groups. The backbone assignment of HMGB1 A-box was achieved with 3D NMR techinques. The 15N-labeled HMGB1 A-box was titrated with MTSL-labeled Hoxc9DBD respectively. Based on the chemical shift changes we can identify the interacting residues and further map out the binding sites on the protein structure. The NMR titration result showed that the binding interface of HMGB1 A-box is around loop-1 between helix-1 and helix-2. In addition, the additional contacts were found in N- and C-terminus. The N-terminal arm region of Hoxc9DBD is the major binding region and the loop between helix1 and helix2 is the minor binding region.

Structure-Activity Relationship of the N-terminal Helix Analog of Papiliocin, PapN

  • Jeon, Dasom;Jeong, Min-Cheol;Kim, Jin-Kyoung;Jeong, Ki-Woong;Ko, Yoon-Joo;Kim, Yangmee
    • Journal of the Korean Magnetic Resonance Society
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    • v.19 no.2
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    • pp.54-60
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    • 2015
  • Papiliocin, from the swallowtail butterfly, Papilio xuthus, shows high bacterial cell selectivity against Gram-negative bacteria. Recently, we designed a 22mer analog with N-terminal helix from $Lys^3$ to $Ala^{22}$, PapN. It shows outstanding antimicrobial activity against Gram-negative bacteria with low toxicity against mammalian cells. In this study, we determined the 3-D structure of PapN in 300 mM DPC micelle using NMR spectroscopy and investigated the interactions between PapN and DPC micelles. The results showed that PapN has an amphipathic ${\alpha}$-helical structure from $Lys^3$ to $Lys^{21}$. STD-NMR and DOSY experiment showed that this helix is important in binding to the bacterial cell membrane. Furthermore, we tested antibacterial activities of PapN in the presence of salt for therapeutic application. PapN was calcium- and magnesium-resistant in a physiological condition, especially against Gram-negative bacteria, implying that it can be a potent candidate as peptide antibiotics.

Modified p-y curves to characterize the lateral behavior of helical piles

  • Hyeong-Joo, Kim;James Vincent, Reyes;Peter Rey, Dinoy;Tae-Woong, Park;Hyeong-Soo, Kim;Jun-Young, Kim
    • Geomechanics and Engineering
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    • v.31 no.5
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    • pp.505-518
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    • 2022
  • This study introduces soil resistance multipliers at locations encompassed by the zone of influence of the helix plate to consider the added lateral resistance provided to the helical pile. The zone of influence of a helix plate is a function of its diameter and serves as a boundary condition for the modified soil resistance springs. The concept is based on implementing p-multipliers as a reduction factor for piles in group action. The application of modified p-y springs in the analysis of helical piles allows for better characterization and understanding of the lateral behavior of helical piles, which will help further the development of design methods. To execute the proposed method, a finite difference program, HPCap (Helical Pile Capacity), was developed by the authors using Matlab. The program computes the deflection, shear force, bending moment, and soil resistance of the helical pile and allows the user to freely input the value of the zone of influence and Ω (a coefficient that affects the value of the p-multiplier). Results from ten full-scale lateral load tests on helical piles embedded at depths of 3.0 m with varying shaft diameters, shaft thicknesses, and helix configurations were analyzed to determine the zone of influence and the magnitude of the p-multipliers. The analysis determined that the value of the p-multipliers is influenced by the ratio between the pile embedment length and the shaft diameter (Dp), the effective helix diameter (Dh-Dp), and the zone of influence. Furthermore, the zone of influence is recommended to be 1.75 times the helix diameter (Dh). Using the numerical analysis method presented in this study, the predicted deflections of the various helical pile cases showed good agreement with the observed field test results.