• 제목/요약/키워드: $3_{10}$-helix

검색결과 212건 처리시간 0.027초

A modified presurgical alveolar molding technique for treatment of cleft in Down syndrome

  • Gonca, Merve;Ozel, Mehmet Birol
    • 대한치과교정학회지
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    • 제51권6호
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    • pp.428-434
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    • 2021
  • Craniofacial clefts are extremely rare deformities. Tessier's classification is a widely accepted system that is based on clinical, radiographical, and surgical observations. The Tessier No. 0 cleft most commonly affects the upper lip, nose, and palate. This case presentation aims to report the outcome of a modified presurgical alveolar molding (PAM) appliance used in the treatment of an infant with Tessier No. 0 cleft as an alternate approach to mold such defects before surgery. The modified PAM appliance consisted of reciprocal parts connected by a helix. The segments were approximated by stripping the appliance at the midline in a V-shaped manner and the force was exerted by the extraoral elastics. The procedure gave results in 8 weeks, which may be regarded as a reasonable duration. The anterior cleft gap, which was 13 mm before the treatment, was reduced to 3 mm after the treatment by using modified PAM appliance. On a 21-month follow-up period, oral reshaping was regarded successful due to stability of the improved oral mold.

Perceptions of Corporate Social Responsibility and Implications for the Nonprofit Sector

  • Jihyeon Song;Seongho An;Jiwon Suh
    • Journal of Contemporary Eastern Asia
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    • 제22권1호
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    • pp.26-48
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    • 2023
  • While corporate social responsibility (CSR) has been considered an important philanthropic support for nonprofits worldwide, little is known about how perceptions of CSR are associated with actual CSR practices that may benefit nonprofit organizations in different institutional contexts. This study applies stakeholder theory to examine how South Korean firms perceive CSR outcomes, and how these perceptions lead to different CSR practices. We constructed a panel dataset using two waves of the Giving Korea survey of CSR and two additional sources. The results indicate that perceived CSR outcomes may play a critical role in CSR practices: 1) the more financial performance is perceived as an outcome, the more will be donated; 2) the more organizational culture is perceived as an outcome, the greater the engagement in employee volunteering; and 3) the more reputation is perceived as an outcome, the more nonprofit organizations are supported. From the findings, we discuss theoretical implications and provide suggestions for nonprofit organizations.

Agenda Setting between the Public and Government on Weibo: The Case of Shanghai Lockdown during the COVID-19 Epidemic

  • Weiwen Yu
    • Journal of Contemporary Eastern Asia
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    • 제22권2호
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    • pp.39-58
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    • 2023
  • This study examined China's public and government agenda setting in response to the Shanghai lockdown due to the COVID-19 pandemic. It employed content analysis, correlation, and Granger's causality tests to analyze 1,717 Weibo posts published by the public and the Shanghai Municipal Government from March 12 to June 1, 2022. The results showed that (1) pandemic statistics were the central attribute in the government agenda, while civil life, community management, and government and policies were the central attributes in the public agenda; (2) the government's agenda unidirectionally influenced the public agenda in terms of government policy attributes; and (3) the government and public agendas reciprocally influenced each other in terms of economic attributes. This study contributed to the existing literature by examining agenda-setting dynamics in a city closure event during the COVID-19 epidemic. It also extended existing methods by modeling implicit relationships between attributes in the public and government agendas.

TIMELIKE TUBULAR SURFACES OF WEINGARTEN TYPES AND LINEAR WEINGARTEN TYPES IN MINKOWSKI 3-SPACE

  • Chenghong He;He-jun Sun
    • 대한수학회보
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    • 제61권2호
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    • pp.401-419
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    • 2024
  • Let K, H, KII and HII be the Gaussian curvature, the mean curvature, the second Gaussian curvature and the second mean curvature of a timelike tubular surface Tγ(α) with the radius γ along a timelike curve α(s) in Minkowski 3-space E31. We prove that Tγ(α) must be a (K, H)-Weingarten surface and a (K, H)-linear Weingarten surface. We also show that Tγ(α) is (X, Y)-Weingarten type if and only if its central curve is a circle or a helix, where (X, Y) ∈ {(K, KII), (K, HII), (H, KII), (H, HII), (KII , HII)}. Furthermore, we prove that there exist no timelike tubular surfaces of (X, Y)-linear Weingarten type, (X, Y, Z)-linear Weingarten type and (K, H, KII, HII)-linear Weingarten type along a timelike curve in E31, where (X, Y, Z) ∈ {(K, H, KII), (K, H, HII), (K, KII, HII), (H, KII, HII)}.

한국에서 분리된 Leptospira의 배양조건에 따른 형태변화 (Effects of Culture Temperatures and Media on Morphological Changes of Leptospira interrogans Isolated in Korea)

  • 이태윤;박전한;엄정란;이봉기;이원영;김주덕;윤정구;한규웅
    • 대한미생물학회지
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    • 제22권3호
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    • pp.209-218
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    • 1987
  • Leptospira interrogans, the causative organism of leptospirosis, is characterized by a fine helical morphology, and the helix is almost always right-handed. However, one of the striking features of recent isolates of L. interrogans in Korea was the heterogeneity in their morphology. Even under optimal culture conditions($30^{\circ}C$, EMJH medium), rods, spiral forms with right or left-handed helices, and even spherical forms of L. interrogans were present. Although the literature notes the presence of left-handed helices, long rods, and spherical forms in cultures of L. interrogans isolates, little is known about the cause of this morphologic heterogeneity. In an attempt to answer this question, this study was initiated to examine the effects of culture conditions, especially temperature and medium, on the morphology of L. interrogans. Four temperatures($5^{\circ}C$, $15^{\circ}C$, $30^{\circ}C$, and $37^{\circ}C$) and two types of media(Fletcher and EMJH) were used; one strain from Korean isolates and L. interrogans serovar canicola obtained from the Pasteur Institute(Paris, France) were employed throughout the study. The findings are as follows: 1. The L. interrogans isolated in Korea(UM-19) had a larger cell diameter($0.25{\sim}0.30\;{\mu}m$: $0.10{\sim}0.15\;{\mu}m$), and helix diameter($0.10{\sim}0.60\;{\mu}m$: $0.10{\sim}0.15\;{\mu}m$) than that obtained from the Pasteur Institute, but they varied in their distances between the helices($0.31{\sim}1.00\;{\mu}m$: $0.50{\sim}0.70\;{\mu}m$). 2, When UM-19 was grown at $37^{\circ}C$ after months or longer preincubation at $5^{\circ}C$ or $15^{\circ}C$, the majority of the organisms were spiral forms; however, they became rods when subcultured at $30^{\circ}C$ or $37^{\circ}C$. No significant morphological differences were found between Fletcher and EMJH media. 3. When L. interrogans serovar canicola was subcultured more than ten times at $37^{\circ}C$, some of the organism lost their motility as well as the hooks at either one or both ends, but only in Fletcher medium. The number of variants increased with the frequency of subculturing. These findings suggested that L. interrogans strain (UM-19) is different, in their morphology, from that of the Pasteur Institute, and its various morphologies may represent stages of the life cycle and vary with incubation temperature.

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토양굴취력이 향상된 스크류형 경량 식혈기 개발(I) - 설계 및 제작 - (Development of Screw-Type Handy Earth Auger for an Improved Digging Efficiency(I) - Design and Manufacture -)

  • 김진현;이재현;김기동;고치웅;김동근
    • 농업생명과학연구
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    • 제50권3호
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    • pp.31-41
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    • 2016
  • 본 연구는 산림조성사업에 있어서 가장 큰 비중을 차지하는 인건비와 생산비용을 절감시키고 경사가 험준한 우리나라 산림지형에서 유용하게 이용 가능한 경량 식혈기를 개발하고자 수행하였다. 제작된 1차 시제품은 토양을 굴취하는 스크류(screw) 부분과 동력원인 배터리로 구성되고, 제원은 스크류의 길이 170mm, 상단폭 60mm, 하단폭 47mm, 나선각(Helix angle)은 23°, 그리고 Tip은 송곳형태로 길이 50mm로 설계·제작하였고 무게를 줄이기 위해 1줄 스크류를 채택하였다. 또한, 동력원으로는 회전용 DC Motor(WD-6G2425, WONILL, Korea)로 최대 Torque는 30㎏f-cm, 회전속도는 20~30rpm으로 설정하였다. 감속비는 30:1의 K6G30C 감속기에 무부하 상태로 사용한 결과 48시간 작동하였다. 그리고 배터리는 경량식재기의 개발을 목표로 하기 때문에 무게를 고려하여 리듐배터리를 사용하였으며, 포트묘의 길이가 15cm 내외인 점을 고려하면 스크류의 회전력이 최대 100kgf-cm정도로 설계하였다. 1차 시제품의 성능을 평가하기 위해 조사지에서 굴취시 스크류에 소요되는 회전력을 측정한 결과, 회전력이 가장 큰 곳은 A area(단단한 초지), 그 다음은 F area(경사가 40°인 산지), E area(경사가 30°인 산지)의 순서로 나타났다. 토양의 굴취 회전력은 일반적으로 깊이가 깊어질수록 높아지는 경향을 보이고 있으며, 대체적으로 토양의 깊이 10cm 부근에서 높은 경향을 보였다.

CgGH insertion functional domain analysis in transgenic G1 and G2 and G3 mutiara catfish (Clarias gariepinus) broodstock

  • Buwono, Ibnu Dwi;Grandiosa, Roffi;Mulyani, Yuniar
    • Fisheries and Aquatic Sciences
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    • 제25권1호
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    • pp.1-11
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    • 2022
  • Catfish is one of the most important freshwater fish farming commodities in Indonesia. Higher catfish production can be achieved by cultivating transgenic catfish carrying the growth hormone (GH) gene of African catfish (Clarias gariepinus GH, CgGH). This research focuses on analysis of the presence of the CgGH gene in transgenic G1, G2, and G3 mutiara catfish broodstock, as an indication of stable CgGH inheritance. CgGH gene was isolated using the RNeasy mini kit and RT-PCR. RT-PCR revealed amplicons measuring approximately 600 bp in transgenic G0, G1, G2, and G3 mutiara catfish. The CgGH consensus sequence similarities ranged from 93.76% to 97.06%, with four functional domain sites (somatotropin-1, somatotropin-2, four α-helix, N-glycosylation, four cysteine residues) of fish GH proteins. The functional domains of fish GH proteins are conserved in G1, G2, and G3 and indicate stable exogenous GH inheritance to produce transgenic catfish strains in each generation.

Solution State Structure of pB1, the Mimotopic Peptide of Apolipoprotein B-100, by NMR

  • Lee, Sung-Ran;Kim, Dae-Sung;Kim, Hyo-Joon;Lee, Yong-Woo;Won, Ho-Shik
    • Bulletin of the Korean Chemical Society
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    • 제25권12호
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    • pp.1845-1849
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    • 2004
  • Apolipoprotein B-100 (Apo-B100) is a major protein component for low density lipoproteins (LDL). A number of mimetic peptides of Apo-B100 were screened from the phase-displayed random peptide library by utilizing monoclonal antibody (B9). Mimetic peptide for B9 epitope against apo B-100 was CRNVPPIFNDVYWIAF (pB1). From the BLAST search, the mimetic peptide pB1 had 40% homology with apo B-100. As a result of the structural determination of this mimotope using homo/hetero nuclear 2D-NMR techniques and NMR-based distance geometry (DG)/molecular dynamic (MD) computations, DG structure had low penalty value of 0.3-0.6 ${\AA}^2$ and the total RMSD was 0.5-1.5 ${\AA}. Moreover, pB1 structure included a weak $3_{10}$-helix from $Ile^7$,/TEX> to $Trp^{13}$.

트롬본 장치를 이용한 하악궁 확장 (Expansion of the mandibular arch using a trombone appliance)

  • Sabuncuoglu, Fidan Alakus;Karacay, Seniz;Olmez, Huseyin
    • 대한치과교정학회지
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    • 제41권3호
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    • pp.211-218
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    • 2011
  • Objective: This case report describes orthodontic treatment of contracted mandibular arch using a trombone appliance. Methods: A 14-year-old girl with Class II division 2 malocclusion, retroclined maxillary incisors, and buccally displaced maxillary canines required dental expansion in 3 spatial directions to correct the contracted maxillary and mandibular arches. In the initial phase of treatment, the maxillary arch was expanded and distalized using a quad-helix appliance and cervical headgear. Following the expansion and leveling of the maxillary arch, a trombone appliance was used to expand the mandibular arch. On correction of the mandibular arch and provision of sufficient space to level the mandibular teeth, fixed orthodontic treatment phase was initiated. Results: A trombone appliance proved effective in correcting the contracted mandibular arch. Because of labiolingual and transversal expansion, the mandibular dental arch perimeter was increased by 7.4 mm; the misalignment of the mandibular teeth was corrected successfully. Conclusions: A trombone appliance may serve as an appropriate clinical alternative for treating moderate mandibular arch crowding caused by the contraction of the dental arch.

Site-directed mutagenesis에 의한 PrrB histidine kinase의 신호인지 기능에 관련된 아미노산의 발굴 (Identification of Amino Acids Involved in the Sensory Function of the PrrB Histidine Kinase by Site-directed Mutagenesis)

  • 김용진;고인정;오정일
    • 생명과학회지
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    • 제16권3호
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    • pp.485-492
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    • 2006
  • 광합성세균인 Rhodobacter sphaeroides의 PrrBA two-component system은 산소분압의 변화에 따라 광합성 유전자의 발현을 조절하는 주요한 조절계 중 하나이다. PrrBA two-component system은 PrrB histidine kinase와 PrrA response regulator로 구성되어 있는데, PrrB의 N-말단 transmembrane 도메인은 신호인지 도메인으로서, 여섯 개의 transmembrane helix가 세 개의 periplasmic loop와 두 개의 cytoplasmic loop을 형성하고 있다. 그 중 세 번째, 네 번째 transmembrane helix와 두 번째 periplasmic loop가 산화/환원 인지 기능에 있어 중요한 역할을 할 것이라고 제안되었다. 본 연구에서는, 두 번째 periplasmic loop와 그 인접 부위에서의 돌연변이 (Asp-90, Gln-93, Leu-94, Leu-98, Asn-106)에 의해 PrrB의 인지 기능에 있어 심각한 결함이 생기는 것을 증명하였고, 이는 이 아미노산들이 PrrB의 산화/환원 인지 기능에 연관되어 있을 수 있다는 것을 보여준다. PrrB의 돌연변이 형태 (D90E, D90N, D90A)가 대장균에서 과발현되어서 affinity chromatography에 의해 정제되었고, 정제된 단백질의 자가인산화 반응이 측정되었다. PrrB D90N 변이형태는 PrrB wild-type보다 높은 자가인산화 활성을 가지는 반면에, PrrB D90E 변이형태는 PrrB wild-type보다 낮은 자가인산화 활성을 나타내었다. 그리고 D90A 변이형태는 PrrB의 자가인산화 활성이 매우 약화되었다.