• Korean Journal of Applied Biomechanics
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• v.25 no.4
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• pp.413-421
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• 2015

Objective : The purpose of this study was to investigate biomechanical changes of the lower limb including dynamic stability with changes in illumination (300Lx, 150Lx, and 5Lx) and slope (level and $15^{\circ}$ downhill) as risk factors for elderly falls. Method : Fifteen elderly females were selected for this study. Seven infrared cameras (Proreflex MCU 240: Qualisys, Sweden) and an instrumented treadmill (Bertec, USA) surrounded by illumination regulators and lights to change the levels of illumination were used to collect the data. A One-Way ANOVA with repeated measures using SPSS 12.0 was used to analyze statistical differences by the changes in illumination and slope. Statistical significance was set at ${\alpha}=.05$. Results : No differences in the joint movement of the lower limbs were found with changes in illumination (p>.05). The maximum plantar flexion movement of the ankle joints appeared to be greater at 5Lx compared to 300Lx during slope gait (p<.05). Additionally, maximum extension movement of the hip joints appeared to be greater at 5Lx and 150Lx compared to 300Lx during slope gait (p<.05). The maximum COM-COP angular velocity (direction to medial side of the body) of dynamic stability appeared to be smaller at 150Lx and 300Lx compared to 5Lx during level gait (p<.05). The minimum COM-COP angular velocity (direction to lateral side to the body) of dynamic stability appeared smaller at 150Lx compared to 5Lx during level gait (p<.05). Conclusion : In conclusion, elderly people use a stabilization strategy that reduces walk speed and dynamic stability as darkness increases. Therefore, the changes in illumination during gait induce the changes in gait mechanics which may increase the levels of biomechanical risk in elderly falls.

• Journal of Microbiology
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• v.40 no.3
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• pp.219-223
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• 2002

In order to investigate the function of Soo1p/${\alpha}$-COP during post-translational modification and intra-cellular transport of cell wall proteins in Saccharomyces cerevisiae, cell wall proteins from the soo1-1/ret1-1 mutant cells were analyzed. SDS-PAGE analysis of biotin labeled cell wall proteins suggested that the soo1-1 mutation impairs post-translational modification of cell wall proteins, such as N- and/ or Ο-glycosylation. Analysis of cell wall proteins with antibodies against ${\beta}$-1,3-glucan and ${\beta}$-1,6-glucan revealed alteration of the linkage between cell wall proteins and ${\beta}$-glucans in the soo1-1 mutant cells. Compositional sugar analysis of the cell wall proteins also suggested that the soo1-1 mutation impairs glycosylation of cell wall protein in the ER, which is crucial for the maintenance of cell wall integrity.

• Korean Journal of Applied Biomechanics
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• v.31 no.3
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• pp.220-225
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• 2021

Objective: The purpose of this study was to investigate the effect of levels of education on ground reaction force and center of pressure parameters during chest compression resuscitation. Method: Twenty male university students were divided into two groups; certified group (CG, n=10) and non-certified group (NCG, n=10). Two force plates were used to measure ground reaction force and center of pressure parameters during 30 times (three trials) chest compression resuscitation. Independent t-tests were used to compare ground reaction force and center of pressure parameters between two groups. An alpha level of 0.05 was used in all tests. Results: All chest-compression time parameters (total time, 1 systolic time, and diastolic time) in CG were significantly shorter than those in NCG (p<.05). Fy of the diastolic and Fz of the systolic in CG revealed significantly the larger GRF values and Fy of the systolic in CG showed significantly the smaller GRF value (p<.05). The standard deviation of Fz of the systolic and diastolic within the subject during 30 times chest-compression resuscitation revealed significantly the smaller values in CG (p<.05). Conclusion: First, CG performed chest compressions efficiently at an appropriate rate compared to NCG. Second, CG showed lower Fx and Fy values in both the mediolateral and anteroposterior axes compared to NCG, which reduced unnecessary chest-compression force consumption and minimized the movement in patients with cardiac arrest. Third, CG showed high Fz value of the systolic and low Fz value of the diastolic. Based on this, chest compression resuscitation was performed to increase the survival rate of cardiac arrest patients.