• Title/Summary/Keyword: ${\alpha}$-Bromoketone

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Synthesis, Anticancer and Antioxidant Activity of Novel 2,4-Disubstituted Thiazoles

  • Tran, Nguyen Minh An;Kumar, Mungara Anil;Chang, Seung Hyun;Kim, Mi Yeong;Kim, Jung-Ae;Lee, Kap Duk
    • Bulletin of the Korean Chemical Society
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    • v.35 no.6
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    • pp.1619-1624
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    • 2014

  • A new series of carbazole based 2,4-disubstituted thiazole derivatives were synthesized. All the synthesized compounds were tested for their cytotoxicity against three different cancer cell lines A549, MCF-7, and HT29. Some of these compounds showed good cytotoxicity. These compounds were also evaluated for antioxidant activity. Compounds 3a, 3b, 3d-f and 3i showed higher antioxidant activity than standard BHT.

  • https://doi.org/10.5012/bkcs.2014.35.6.1619 인용 PDF KSCI KPUBS HTML