• Nuclear Medicine and Molecular Imaging
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• 제40권6호
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• pp.327-331
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• 2006

목적: 흡인 영상법은 흡인의 유무를 확인하고 흡인된 물질의 양을 정량화하기 위한 핵의학적 영상법이다. 본 연구의 최종 목적은 흡인 영상법으로 흡인과 흡인성 폐렴의 상관관계를 규명하는 것이고, 이 논문은 그 시도에 대한 예비적 보고이다. 대상 및 방법: 비디오투시연하검사에서 양성으로 확인된 10명의 환자들을 선택하였다 환자들이 Tc-99m tin colloid 92.5 MBq (2.5 mCi)을 넣은 반고형식을 먹은 직후 초기영상을 얻었고, 3시간 후에 지연영상을 얻었다. 식사한 양에 대한 흡인량의 비율인 흡인분율을 붕괴 보정을 이용한 방정식에 의하여 계산하였다. 결과: 5명의 환자들이 흡인 영상법에 의해 양성으로 판독되었다. 4명은 초기영상에서만 양성으로 판독되었고, 1명은 초기영상과 지연영상 모두에서 양성으로 판독되었다. 흡인분율은 0.11%, 0.11%, 0.81%, 그리고 0.11% 였다. 초기영상과 지연영상 모두에서 흡인된 환자의 흡인분율은 초기에 5.82%, 지연에 2.26% 였다. 결론: 흡인 영상법에 의해 시간의 경과에 따라 흡인의 위치를 확인할 수 있고 흡인된 물질의 양을 정량화 할 수 있다. 앞으로 환자에 대한 추적관찰이 필요하다.

• 대한핵의학회지
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• 제21권1호
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• pp.9-16
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• 1987

It is well-known that hepatic scintigraphv have been found to be less sensitive and specific in the detection of the diffuse hepatocellular diseases than that of the space-occupying lesions. To obtain the higher diagnostic specificity and sensitivity, we, using the computer quantitation, have attempted to analyze hepatic and extrahepatic $^{99m}Tc-tin$ colloid uptake patterns in various diffuse hepatocellular diseases retrospectively. The studied groups consisted of 116 cases of normal, 67 cases of acute hepatitis, 112 cases of chronic hepatitis, 61 cases of liver cirrhosis, 47 cases of fatty liver, 12 cases of hepatoma and 9 cases of metastasis, making total 424 cases. Scintigraphic imagings were obtained in the anterior, right lateral and posterior projections using high-resolution collimation, and simultaneously these gamma data were acquisited into the computer system. Both large region of interest (ROI) using light pen and ROI computer program were placed over right lobe, left lobe of liver, spleen and cardiac blood pool. Total counts in ROI were divided by the number of pixels in the ROI, and mean count rate per pixels calculated. Mean right-lobe counts were divded by mean-left lobe counts to determine right-to-left hepatic lobe ratio and mean spleen counts were divided by mean liver counts to determine spleen to liver ratio. The results were as follows. 1) Of 424 cases, 292 were male and 132 were female. The majority of age distribution was in $30\sim49$ (54.5%). 2) Inter-observer between two independant operators and inter-method between drawing by light-pen and ROI computer program variations were not significant. 3) The uptake count values (per pixel) determined at each area in normal group were $106.53{\pm}18.35$ in right lobe, $79.00{\pm}13.82$ in left lobe, $17.52{\pm}8.31$ in spleen and $8.09{\pm}3.43$ in cardiac blood pool. 4) In liver cirrhosis, right lobe uptake was decreased but spleen and cardiac blood pool uptakes were increased (p<0.01). 5) Right-to-left hepatic lobe uptake ratio was $1.37{\pm}0.24$ in normal group and significantly low in chronic hepatitis, liver cirrhosis and fatty liver, and more or less low in acute hepatitis. 6) Spleen-to-right hepatic lobe uptake ratio was $0.17{\pm}0.09$ in normal group and high in chronic hepatitis and liver cirrhosis. 7) The computer-quantitation of hepatic and extrahepatic uptake patterns thought to be sensitive and useful method in the interpretation of liver scintigram.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 2002년도 제41차 추계학술대회
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• pp.30.1-30.1
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• 2002

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 2004년도 추계학술대회 및 총회
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• pp.415.2-415.2
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• 2004

• 대한핵의학회지
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• 제27권2호
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• pp.309-314
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• 1993

저자등은 33세 남자 환자에서 검사실 소견과 복부 전산화 단층촬영, 간 신티그라피 및 골주사, 복부 초음파 및 수술소견을 통해 알콜성 및 C형 간염에 의한 간경화를 동반한 환자가 교통사고로 복부 외상에 의한 간하부열상을 받아 복강내출혈로 입원한 환자에서 일시적으로 골주사소견에서 비장에 섭취를 보이는 것이 복부 비장의 잠재적 외상으로 인한 것으로 사료되며, 비장 비대 외에는 특이소견이 보이지 않으며 기전이 명확하지 않은 골주사상 비장섭취를 보인 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Nuclear Medicine and Molecular Imaging
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• 제43권1호
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• pp.55-59
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• 2009

목적: 전초림프절 스캔과 전초림프절 생검은 유방암 환자에서 액와림프절 전이를 인지하기 위해서 사용되지만, 표준화된 방법이 마련되어 있지 않다. 액와림프절 전이를 인지하기 위한 전초림프절 검사에 있어서 본 연구에서는 수술당일 주사하는 당일검사와 수술전날 주사하는 전날검사의 결과를 비교하여 보았다. 대상 및 방법: 본 연구에서는 2001년에서 2004년사이에 유방암으로 수술을 시행했던 349명의 환자를 대상으로 하였다. 171명의 환자는 Tc-99m Tin-Colloid (37 MBq) 0.8 ml를 유륜하로 수술당일(1시간 전)에 주사하였다. 178명의 환자는 Tc-99m Tin-Colloid (185 MBq) 0.8 ml를 유륜하로 수술전날(16시간 전)에 주사하였다. 앉은 자세에서 림프신티그라피가 시행되었고, 수술 중에 감마프로브로 전초림프절을 발견하였다. 결과: 당일검사를 시행한 전체 171명의 환자 중에서 153명(89.5%)이 림프신티그라피에 의해 전초림프절이 발견되었고, 150명(87.7%)이 감마프로브에 의해 전초림프절이 발견되었다. 전날검사를 시행한 전체 178명의 환자 중에서 159명(89.3%)이 림프신티그라피에 의해 전초림프절이 발견되었고, 154명(86.5%)이 감마프로브에 의해 전초림프절이 발견되었다. 당일검사와 전날검사에 있어서, 림프신티그라피와 감마프로브에 의한 전초림프절 발견율의 유의한 차이는 없었다(p>0.05, p>0.05). 결론 : 유방암 환자에서 전초림프절을 발견하는데 있어 당일검사와 전날검사에 의한 차이는 없었다. 전날검사는 전초림프절 스캔을 시행할 충분한 시간을 얻을 수가 있어서, 유방암 환자에서 전초림프절을 발견하는데 더 유용할 것이다.

• 대한핵의학회지
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• 제20권1호
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• pp.39-43
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• 1986

[ $^{99m}Technetium-Heat$ ] damaged erythrocyte were used as spleen scanning agents in 12 patients from July, 1985 to April, 1986. We used this scan to evaluate situs inversus, asplenia, accessory spleen, hypersplenism, splenic infarction, tumor staging and evaluation of therapy, especially when the $^{99m}Tc-tin$ colloid scans were not definite for diagnosis. The techniques applied to these scans were in vivo/in vitro-labeling method and heating-method to damage the erythrocytes. Liver-to-spleen uptake ratios were increased upto 100 : 1 and interference from the left lobe of the liver was eliminated. These scans were helpful to evaluate the spleen.

• 대한핵의학회지
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• 제22권2호
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• pp.193-197
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• 1988

Measurement of gastric emptying rate has been performed by a variety of techniques. Nuclear medicine method is a major advance in the quantitative evaluation of gastric function and also of pharmacologic intervention. Normal gastric emptying rate was measured in 48 healthy volunteers using live chicken liver labeled with $^{99m}Tc-Tin$ Colloid as a solid phase marker. In vitro studies were performed to evaluate the labeling efficiency and stability in hydrochloric acid and in human gastric juice of intracellularly labeled chicken liver. Anterior image counts only were compared with the geometric mean of anterior and posterior counts in 12 healthy volunteers who were studied by both anterior count and posterior count. The results were as follows: 1) The labeling efficiency in gastric juice and hydrochloric acid were $95.5{\pm}1.23%,\;95.7{\pm}1.15%$, respectively. 2) Half gastric emptying time by anterior count only was $126{\pm}21$ minutes 3) Although standard deviation of geometric mean method was smaller than anterior count method, gastric emptying curves from both method were similar. In daily practice, anterior count method may be useful alternative to geometric mean method in evaluation of gastric emptying rate.

• 대한핵의학회지
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• 제27권2호
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• pp.233-238
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• 1993

Esophageal motility was evaluated from the analysis of 10 consecutive swallows using liquid bolus containing 0.5 mCi of $^{99m}Tc$ tin colloid. We have reviewed our experience of esophageal transit study in the 20 normal volunteers and 55 patients with dysphagia that was not related to mechanical obstruction. The purpose of this study is to measure the esophageal transit in normal subjects and in patients with various esophageal motility disorders. The overall sensitivity and specificity of radionuclide esophageal transit study in detecting esophageal motor abnormality were compared with manometric results as a gold standard, which were 80% and 100% respectively. Radionuclide transit study is a safe, rapid, noninvasive test and suitable as a screening test for esophageal motor disorders.

• 대한핵의학회지
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• 제26권2호
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• pp.392-395
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• 1992

Hepatic hydrothorax is defined as the presence, in a cirrhotic patient, of a large pleural effusion in the absence of primary pulmonary or cardiac disease. Pleural effusions occur in 5% to 10% of patients with cirrhosis of the liver. The effusions are usually right-sided, but may be bilateral or left-sided. The precise mechanism of fluid accumulation is not clear. We reported a case of right hepatic hydrothorax occuring in the liver cirrhosis with ascites. Diagnosis was confirmed by the intraperitoneal and intrapleural injection of radioisotope $^{99m}Tc-tin$ colloid that demonstrated the one-way transdiaphragmatic flow of fluid from the peritoneal to pleural cavities.