• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.6
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• pp.1388-1394
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• 2014

Recently, medical expenses are increasing because of the accelerated aging phenomenon, thus study for the medical service of high quality and reduction of medical expenses should be continued as yet. Especially, U-health is performed by intelligent medical service which is derived by smart devices, wireless network, sensing technology and it could be more extensible in the medical fields as time goes on. On this study, we analyze message transmission structure of HL7 standard and will suggest improved processing methodology of HL7 message.

• Journal of The Korean Astronomical Society
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• v.7 no.1
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• pp.11-15
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• 1974

An attempt has been made to re-evaluate the photospheric iron abundance by comparing computed, theoretical line profiles with observations. Our resulting abundance is found to be in good agreement with that of Garz and Kock (1969), when the logarithmic abundance of iron is taken to be 7.5.

• Journal of applied mathematics & informatics
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• v.13 no.1_2
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• pp.433-440
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• 2003

Artinian O-sequences of codimension 3 and type 3 with length 7 are classified as level or non-level. Some cases are proved to be non-level among the 334 cases which have been suspected to be level.

• BMB Reports
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• v.30 no.5
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• pp.370-377
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• 1997

A novel assay method is described for rapid quantitation of reaction rate of sterol ${\Delta}^7$-reductase (${\Delta}^7$-SR) which catalyzes reduction of the ${\Delta}^7$-double bond of sterols. Of six different organ tissues-liver, small intestine, brain, lung, kidney, and testis-. ${\Delta}^7$-SR activity was detected only in liver (2.30 nmol/min/mg protein) and testis (0.11 nmol/min/mg protein). Using a newly developed method which employs diet-induced enzyme proteins and ergosterol as substrate, we assessed both kinetics ($K_m=210\;{\mu}M$, $V_{max}=1.93\;nmol/min/mg$) and inhibition of the rat hepatic ${\Delta}^7$-SR against well-studied cholesterol lowering agents such as triparanol ($IC_{50}=16\;{\mu}M$). 3-$\beta$-[2-(diethylamino)ethoxy]androst-5-en-17-one (U18666A) ($IC_{50}=5.2\;{\mu}M$), and trans-1.4-bis(2-chlorobenzylaminomethyl)cyclohexane dihydrochloride (AY-9944) ($IC_{50}=0.25\;{\mu}M$). Of the three well-known AY-9944-sensitive cholesterogenic enzymes (i.e., ${\Delta}^7$-SR, sterol ${\Delta}^8$-isomerase, and sterol ${\Delta}^14$-reductase). ${\Delta}^7$-SR was found to be the most sensitive enzyme with a noncompetitive inhibition of this compound ($K_i=0.109\;{\mu}M$). Substrate specificity studies of the microsomal ${\Delta}^7$-SR indicate that the relative reaction rate for 7-dehydrocholesterol and ergosterol are 5.6-fold and 1.6-fold higher than that for lathosterol. ${\Delta}^7$-SR activity was also modulated by feeding rats a diet supplemented with 0.5% ergosterol (>2.6-fold) in addition to 5.0% cholestyramine plus 0.1% lovastatin ($\simeq$5.0-fold). Finally, microsomal ${\Delta}^7$-SR was solubilized by 1.5% 3-[3-(cholamidopropyl)-dimethylammonio]-1-propanesulfonate (CHAPS) and enriched on PEG (0~10%) precipitation, which should be suitable for further purification of the enzyme.

• BMB Reports
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• v.47 no.7
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• pp.399-404
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• 2014

B7-H4 is a member of B7 family of co-inhibitory molecules and B7-H4 protein is found to be overexpressed in many human cancers and which is usually associated with poor survival. In this study, we developed a therapeutic vaccine made from a fusion protein composed of a tetanus toxoid (TT) T-helper cell epitope and human B7-H4IgV domain (TT-rhB7-H4IgV). We investigated the anti-tumor effect of the TT-rhB7-H4IgV vaccine in BALB/c mice and SP2/0 myeloma growth was significantly suppressed in mice. The TT-rhB7-H4IgV vaccine induced high-titer specific antibodies in mice. Further, the antibodies induced by TT-rhB7-H4IgV vaccine were capable of depleting SP2/0 cells through complement-dependent cytotoxicity (CDC) in vitro. On the other hand, the poor cellular immune response was irrelevant to the therapeutic efficacy. These results indicate that the recombinant TT-rhB7-H4IgV vaccine might be a useful candidate of immunotherapy for the treatment of some tumors associated with abnormal expression of B7-H4.

• ETRI Journal
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• v.29 no.2
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• pp.246-248
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• 2007

Query-by-example (QBE) is a well-known method for image retrieval. In reality, however, an example image to be used for the query is rarely available. Therefore, it is often necessary to find a good example image to be used for the query before applying the QBE method. Query-by-layout (QBL) is our proposal for that purpose. In particular, we make use of the visual descriptors such as the edge histogram descriptor (EHD) and the color layout descriptor (CLD) in MPEG-7. Since image features of the CLD and the EHD can be localized in terms of a$4{\times}4$ sub-image, we can specify image features such as color and edge distribution on each sub-image separately for image retrieval without a query image. Experimental results show that the proposed query method can be used to retrieve a good image as a starting point for further QBE-based image retrieval.

• Journal of the Korean Society of Radiology
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• v.7 no.2
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• pp.131-136
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• 2013

Panorama of dental radiation generators can observe the wide anatomical structures of oral and maxillofacial areas but there can be distortion of lengths, angles, or shapes. CBCT can diagnose 3D images and get the ones whose errors by superposition and interference are remarkably smaller between anatomical structures. But the quality of the images by movement of subjects can be lowered as it takes long to diagnose them. And if there are impermeable radiation objects like metal in mouths, impermeable radiation lines can radially appear with the objects as center. This study tries to analyze accuracy of panorama and CBCT and get useful anatomical information in dental treatment by comparing the length of wisdom teeth which were measured by Panorama and CBCT with the teeth which were actually extracted and analyzing distortion of the teeth. The test result could be found that Panorama is expanded by average 7.3% as the errors of Panorama and Digital Vernier Caliper range from 110.7% to 103.9%. The length of wisdom teeth which were measured in CBCT and Digital Vernier Caliper could be found that the error range is 1.3%. And the length of wisdom teeth which were measured in Panorama and Digital Vernier Caliper has found that the error range shows 7.3%. So it could be found that the images of CBCT is about 6% more exact than those of Panorama. It could be found that CBCT shows the more exact images than those of Panorama. But because the examination expenses of CBCT are higher than those of Panorama and exposure dose of CBCT is much more than that of Panorama, it is thought to find proper ways in examination.

• ETRI Journal
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• v.24 no.1
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• pp.23-30
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• 2002

MPEG-7 Visual Standard specifies a set of descriptors that can be used to measure similarity in images or video. Among them, the Edge Histogram Descriptor describes edge distribution with a histogram based on local edge distribution in an image. Since the Edge Histogram Descriptor recommended for the MPEG-7 standard represents only local edge distribution in the image, the matching performance for image retrieval may not be satisfactory. This paper proposes the use of global and semi-local edge histograms generated directly from the local histogram bins to increase the matching performance. Then, the global, semi-global, and local histograms of images are combined to measure the image similarity and are compared with the MPEG-7 descriptor of the local-only histogram. Since we exploit the absolute location of the edge in the image as well as its global composition, the proposed matching method can retrieve semantically similar images. Experiments on MPEG-7 test images show that the proposed method yields better retrieval performance by an amount of 0.04 in ANMRR, which shows a significant difference in visual inspection.

• Journal of the Korean Society for Precision Engineering
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• v.29 no.10
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• pp.1119-1127
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• 2012

In this paper, we present an inverse kinematics of a 7-dof Anthropomorphic robot arm using conformal geometric algebra. The inverse kinematics of a 7-dof Anthropomorphic robot arm using CGA can be computed in an easy way. The geometrically intuitive operations of CGA make it easy to compute the joint angles of a 7-dof Anthropomorphic robot arm which need to be set in order for the robot to reach its goal or the positions of a redundant robot arm's end-effector. In order to choose the best solution of the elbow position at an inverse kinematics, optimization techniques have been proposed to minimize an objective function while satisfying the euler-lagrange equation.

• Bulletin of the Korean Chemical Society
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• v.11 no.5
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• pp.379-383
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• 1990

$YBa_2Cu_{3-x}Ni_xO_{7-{\delta}}$, with x = 0.05, 0.2, 0.4, 0.7 and 1.0 had been prepared by the thermal decomposition of corresponding nitrates. Among them, the sample with x = 0.05 shows above-liquid-$N_2$ temperature superconductivity with $T_c$ of 88.7K. According to the X-ray diffraction analysis, its crystal symmetry was estimated as orthorhombic with the lattice parameters of a = 3.866${\AA}$, b = 3.893${\AA}$, c = 11.715${\AA}$. The chemical composition of the sample was determined by electron probe microanalysis and the chemical composition around its grain boundaries was carefully studied by the X-ray line scanning technique. From the observed binding energy of Ni-$2p_{3/2}$ orbital electron (B.E. = 853 eV) measured by X-ray photoelectron spectroscopy, the valency state of nickel stabilized in $YBa_2Cu_{2.95}Ni_{0.05}O_{7-{\delta}}$ oxide lattice could be determined to be Ni(II).