• Title/Summary/Keyword: $^{123}In$

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Evaluation of Hemodynamic Failure with Acetazolamide Challenged $^{123}I-IMP$ Brain SEPCT and PET (PET과 Acetazolamide 부하 $^{123}I-IMP$ 뇌혈류 SPECT를 이용한 혈역학적 부전의 평가)

  • Chun, Kyung-Ah;Cho, In-Ho;Won, Kyu-Jang;Lee, Hyung-Woo;Hayashida, Kohei
    • The Korean Journal of Nuclear Medicine
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    • v.37 no.2
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    • pp.94-102
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    • 2003
  • Purpose : Cerebral blood flow (CBF) reactivity to acetazolamide (ACZ) is useful to select patients with hemodynamic failure. However, it is still a matter of speculation that varying degrees of regional CBF increases after ACZ administration represent the severity or stage of regional hemodynamic failure as assessed by positron emission tomography (PET). We studied to elucidate whether ACZ challenge $^{123}I-IMP$ brain single photon emission tomography (SPECT) can accurately grade the seventy of regional hemodynamic failure. Materials and Methods: Eighteen patients (M: 16, F: 2, average age: 61 years) with unilateral occlusive disease of the internal carotid artery or the trunk of the middle cerebral artery (MCA). Patients undewent $^{123}I-IMP$ brain SPECT study with acetazolamide challenge and PET study was carried out within 2 weeks before and after SPECT study. Five healthy volunteers with a mean age of 48 years (range: 28-73 yr, M: 3, F: 2) underwent PET studies to determine normal values. In SPECT study, an asymmetry index (Al)-the percentage of radioactivity of region of interest (ROI) in the occlusive cerebrovascular lesion to the contralateral homologous ROI-was used for numerical evaluation of relative $^{123}I-IMP$ distribution. In PET study, regional CBF, oxygen extraction fraction (OEF), cerebral metabolic rate of oxygen ($CMRO_2$) and cerebral blood volume (CBV) values were measured with $^{15}O-labeled$ gas inhalation method and the values were used for comparison with Al (Al during acetazolamide challenge-Al of basal study) on the SPECT study. ROls were classified by severity into three groups (normal, stage I and stage II). Results: Mean values of Al in areas with normal, stage I and stage II hemodynamic failure were $6.25{\pm}7.77%\;(n=107),\;-10.38{\pm}10.41%\:(n=117)\;and\;13.30{\pm}10.51%\;(n=140)$, respectively. Al significantly differed with each groups (p<0.05). Correlation between Al and CBF, OEF and CBV/CBF in hemisphere with occlusive cerebrovascular lesion was 0.20 (p<0.01), -0.28 (p<0.01) and -0.28 (p<0.01), respectively. Conclusion: We concluded that $^{123}I-IMP$ brain SPECT with acetazolamide challenge could determine the severity ad stage of regional hemodynamic failure as assessed by PET.

Effects of $BaCO_3$ purity on the superconducting properties of top seeded melt growth processed $Y_{1+x}Ba_2Cu_3O_y$ superconductors

  • Choi, J.S.;Park, S.D.;Jun, B.H.;Han, Y.H.;Sung, T.H.;Choo, K.N.;Kim, C.J.
    • Progress in Superconductivity and Cryogenics
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    • v.11 no.2
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    • pp.7-10
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    • 2009
  • Effects of $BaCO_3$ purity on the superconducting properties of top seeded melt growth (TSMG) processed $Y_{1+x}Ba_2Cu_3O_{7-y}$ (Y1+x, x=0.1 and 0.2) superconductors were investigated. $YBa_2Cu_3O_{7-y}$ (Y123) powder prepared using $BaCO_3$ with 99.75% purity and commercially available Y123 powder of 99.9% were used for the fabrication of single Y123 grain superconductors. $T_c$ values of the Y1+x samples prepared using low purity Y123 powder were slightly lower than those of the samples prepared using a high purity powder. In addition to the lower $T_c$, an anomalous peak effect in the intermediate magnetic fields was observed in Y1+x samples prepared using the low purity $BaCO_3$ powder. The slight decrease in $T_c$ and the anomalous peak effect are ascribed to the possible incorporation of a Y123 phase with impurity elements such as strontium and calcium included in the $BaCO_3$powder of 99.7%. The result suggests that the low purity $BaCO_3$ powder of a low price can be used as a raw power for the fabrication of single grain YBCO bulk superconductors.

A Comparison of Genospecies of Clinical Isolates in the Acinetobacter spp. Complex Obtained from Hospitalized Patients in Busan, Korea

  • Park, Gyu-Nam;Kang, Hye-Sook;Kim, Hye-Ran;Jung, Bo-Kyung;Kim, Do-Hee;Chang, Kyung-Soo
    • Biomedical Science Letters
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    • v.25 no.1
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    • pp.40-53
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    • 2019
  • Of the Acinetobacter spp., A. baumannii (genospecies 2) is the most clinically significant in terms of hospital-acquired infections worldwide. It is difficult to perform Acinetobacter-related taxonomy using phenotypic characteristics and routine laboratory methods owing to clusters of closely related species. The ability to accurately identify Acinetobacter spp. is clinically important because antimicrobial susceptibility and clinical relevance differs significantly among the different genospecies. Based on the medical importance of pathogenic Acinetobacter spp., the distribution and characterization of Acinetobacter spp. isolates from 123 clinical samples was determined in the current study using four typically applied bacterial identification methods; partial rpoB gene sequencing, amplified rRNA gene restriction analysis (ARDRA) of the intergenic transcribed spacer (ITS) region of the 16~23S rRNA, the $VITEK^{(R)}$ 2 system (an automated microbial identification system) and matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS). A. baumannii isolates (74.8%, 92/123) were the most common species, A. nosocomialis (10.6%, 13/123) and A. pittii isolates (7.5%, 9/123) were second and third most common strains of the A. calcoaceticus-A. baumannii (ACB) complex, respectively. A. soli (5.0%, 6/123) was the most common species of the non-ACB complex. RpoB gene sequencing and ARDRA of the ITS region were demonstrated to lead to more accurate species identification than the other methods of analysis used in this study. These results suggest that the use of rpoB genotyping and ARDRA of the ITS region is useful for the species-level identification of Acinetobacter isolates.

Thermal Stability of Superconductor NdBCO Sintered at Various Oxygen Partial Pressures (다양한 산소분압에서 소결한 NdBCO 초전도체의 열적 안정성)

  • Chung, J.K.;Kim, W.J.;Park, S.C.;Kang, S.G.;Lim, Y.J.;Kim, C.J.
    • Progress in Superconductivity
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    • v.10 no.2
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    • pp.133-138
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    • 2009
  • The $Nd_{1+x}Ba_{2-x}Cu_3O_{7-{\delta}}$(Nd123) superconductor exhibits high performance in high magnetic field and high temperature. We have studied phase stability for Nd123 under reduced oxygen partial pressure and various heat-treatment conditions. The main phase is Nd123 and some samples contain small amounts of Nd422 depending on the temperature and oxygen partial pressure. The decomposition temperature decreases with decreasing oxygen partial pressure from $1052^{\circ}C(P(O_2)$=150 Torr) to about $845^{\circ}C(P(O_2)$=0.1 Torr). The liquidus line was steeper temperature with decreasing oxygen partial pressure. In same condition of oxygen partial pressure, the region of stable Nd123 phase was formed at slightly higher temperature than the region of stable YBCO phase.

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High $T_c$ Superconductors $LnBa_2Cu_3O_{7-\delta}$ from 2-Ethylhexanoate Precursors (2-Ethylhexanoate 화합물에서 제조한 고온초전도체 $LnBa_2Cu_3O_{7-\delta}$)

  • Jung Ohk Kweon;Soon Bok Hong;Sung Uhk Lee;Jung Sik Oh;Won Yang Chung
    • Journal of the Korean Chemical Society
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    • v.36 no.6
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    • pp.818-823
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    • 1992
  • 2-Ethylhexanoate compounds which contained Y, Er, Yb, Ba, and Cu were prepared separately. These metallo-organic compounds were dissolved together in the common solvent and the solution was homogeneous. From these solution, high $T_c$ superconductors $YBa_2Cu_3O_{7-\delta}(Y_{123})$, $ErBa_2Cu_3O_{7-\delta}(Er_{123})$, and $YbBa_2Cu_3O_{7-\delta}(Yb_{123})$ were prepared. XRD analysis showed that these superconductors were not single phase and contained some impurity phases including $YBa_2Cu_4O_8(Y_{124})$. This was also confirmed from the magnetic susceptibility measurement. Generally, critical temperatures were higher than that of the superconductors prepared by ceramic method. Volume diamagnetic susceptibility showed little variation compared to the specimen made by ceramic method.

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Effect of Germination and Heating on Phytase Activity in Cereal Seeds

  • Ma, Xi;Shan, Anshan
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.7
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    • pp.1036-1039
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    • 2002
  • The effect of germination on phytase activity in wheat NEAU123, triticale5305 and rye2 was studied in the present study. Germination significantly increased phytase activity by 2.04 times for wheat NEAU123 (3 d), 1.82 times for triticale 5305 (1 d) and 2.45 times for rye2 (1 d), respectively. It was safe for phytase in fresh malts kilned for 2 h at $40^{\circ}C$. Phytase in cereal seeds had strong heat stability. There was no loss of phytase activity in cereal seeds heated at $70^{\circ}C$ for 1 h, a little loss (${\leq}$5.46%) at $80^{\circ}C$ or $90^{\circ}C$. Even heated at $100^{\circ}C$, the phytase activity in wheat NEAU123, triticale5305 and rye2 remained 89.47%, 86.44% and 104.64%, respectively.

진공장치용 오링의 압축율 측정

  • Sin, Yong-Hyeon;Im, In-Tae;Im, Jong-Yeon;Hong, Seung-Su;Kim, Jeong-Hyeong;Seong, Dae-Jin;Jeong, Gwang-Hwa
    • Proceedings of the Korean Vacuum Society Conference
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    • 2001.02a
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    • pp.123-123
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    • 2001
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