• The Korean Journal of Nuclear Medicine
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• v.38 no.1
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• pp.41-51
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• 2004

PURPOSE: Tourette's disorder (TD), which is characterized by multiple waxing and waning motor tics and one or more vocal tics, is known to be associated with abnormalities in the dopaminergic system. To testify our hypothesis that risperidone would improve tic symptoms of TD patients through the change of the dopaminergic system, we measured the dopamine transporter (DAT) densities between drug-naive children with TD and normal children, and investigated the DAT density before and after treatment with risperidone in drug-naive children with TD, using iodine-123 labelled $N-(3-iodopropen-2-yl)-2{\beta}-carbomethoxy-3beta-(4-chlorophenyl)tropane$ ($[^{123}I]IPT$) single photon omission computed tomography (SPECT). MATERIALS and METHODS: $[^{123}I]IPT$ SPECT Imaging and Yale Global Tic Severity Scale-Korean version (YGTSS-K) for assessing the tic symptom severity were carried out before and after treatment with risperidone for 8 weeks in nine drug-naive children with TD. Eleven normal children also underwent SPECT imaging 2 hours after an intravenous administration of $[^{123}I]IPT$. RESULTS: Drug-naive children with TD had a significantly greater increase in the specific/nonspecific DAT binding ratio of both basal ganglia compared with the normal children. However, no significant difference in the specific/nonspecific DAT binding ratio of the basal ganglia before and after treatment with risperidone in children with TD was found, although tic symptoms were significantly improved with risperidone. CONCLUSION: These findings suggest that DAT densities are directly associated with the pathophysiology of TD, however, that the effect of risperidone on tic symptoms in children with TD is not attributed to the change of dopaminergic system.

• Korean Journal of Mathematics
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• v.22 no.1
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• pp.123-131
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• 2014

The purpose of this paper is to study the perturbation analysis of the matrix equation $X=I-A^*X^{-1}A+B^*X^{-1}B$. Based on the matrix differentiation, we give a precise perturbation bound for the positive definite solution. A numerical example is presented to illustrate the shrpness of the perturbation bound.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.11a
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• pp.123-125
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• 2011

A SATA hard disk has been widely used in recent years and NCQ is one of its crucial features. Despite the development from IDE to SATA disk, there is still much room for improvement for a SATA disk. In addition, until now a hard disk is a black box to us and it is very hard to make research at the level of a disk controller. To enhance the performance of NCQ, we try to do I/O clustering over the requests, which combines multiple sequential requests into a single large one. To evaluate the effect of an I/O clustering mechanism, we created a simple but practical SATA hard disk simulator. Experimental results show that the proposed approach is effective in enhancing the I/O performance of a SATA disk.

• Journal of Korean Medical classics
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• v.31 no.3
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• pp.123-142
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• 2018

Objectives : This paper aims to study the I-Ching perspective in Shanghansuyuanji. Methods : Key words associated with I-Ching was searched in Shanghansuyuanji and analyzed its meaning and categorized thematically. Results & Conclusions : 1. Qianhuang symbolized Shaoyang, The Power of the Great hexagrams, Jueyin Peace hexagrams, Taiyin Gen Earth, Yangming Kun Earth, Shaoyin Return hexagrams, but didn't symbolize Taiyang, making it not uniform. 2. Qianhuang explained physiology focusing the change of YangQi with I-Ching perspective. This is possible because Shanghanlun thought that much of YangQi and I-Ching set a high value on Yang. 3. Qianhuang explained pathology such as insomnia, epigastric fullness, splenic constipation syndrome, Taiyinbing syndrome, somnolence, thirst, YinYang exchange with I-Ching perspective, it is meaningful because it enriches medical YinYanglun. 4. Qianhuang explained prescriptions such as Daqinglongtang, Zhenwutang, Shizaotang, Fuzixiexintang, Dachaihutang, Baihutang, a comparison between Daqinglongtang and Xiaoqinglongtang with I-Ching perspective. This is helpful to grasp the image of prescriptions. 5. Qianhuang explained nature of drugs such as Guizhi, Fuling, Fuzi, Qiandan, Rougui with I-Ching perspective, and it combines well with the features of I-Ching with drugs efficacy. 6. Qianhuang explained diseases of the six Meridians curing time with I-Ching perspective. This shows diseases of the six Meridians recover when Corresponding Qi is vigorous or Conflict Qi appears, and it is persuasive. For reasons mentioned above; Shanghansuyuanji is meaningful as Shanghanlun commentary.

• Water for future
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• v.31 no.1
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• pp.123-129
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• 1998

• TTA Journal
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• s.103
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• pp.123-127
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• 2006

• Monthly Korean Chicken
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• v.14 no.11
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• pp.120-123
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• 2008

• Monthly Korean Chicken
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• v.16 no.1
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• pp.123-129
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• 2010

• Monthly Korean Chicken
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• v.17 no.11
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• pp.120-123
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• 2011

• Journal of radiological science and technology
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• v.24 no.2
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• pp.35-40
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• 2001

Performance of SPECT imaging systems which use a rotating gamma camera, are affected by characteristics of the detector-collimator assembly, the data acquisition method, and the filter used in imaging reconstruction. The purpose of this study Is to examine image qualifies of SPECT with different types of low energy collimators. The SPECT imaging system in this study is a digital gamma camera system GCA-901A(Toshiba) and a data processing unit Scintipac-700(Shimadzu). The four types of collimators compared are UHR(ultra high resolution), LEHR(low energy high resolution), LEGP(low energy general purpose), and I-123 PAR(Parallel), with 0.27, 0.66, 1.00, and 2.06 relative sensitivity, respectively. In this case of the same collimators, the spatial resolutions measured in the slice plane showed a slight difference in the FWHM values(mean values of UHR, LEHR, LEGP, and I-123 PAR were 11.3 mm, 13.6 mm, 15.8 mm, and 20.4 mm, respectively) between the center and the circumference of the field of view, in the radial direction, but a large difference in the tangential direction, with lower FWHM values(values of UHR, LEHR, LEGP, and I-123 PAR were 8.4 mm, 8.7 mm, 9.3 mm, and 10.8 mm at 12 cm from the center, respectively). In comparison of SPECT images with the four types of collimators, except for the I-123 PAR collimator, image qualities of UHR, LEHR, and LEGP collimators showed only a slight difference. From the point of for, it is expected that the LEGP collimator would be suitable for SPECT imaging with $^{99m}Tc$.