• Title/Summary/Keyword: "Challenged"

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Effects of dietary supplementation of Pediococcus pentosaceus strains from kimchi in weaned piglet challenged with Escherichia coli and Salmonella enterica

  • Dongcheol Song;Jihwan Lee;Kangheung Kim;Hanjin Oh;Jaewoo An;Seyeon Chang;Hyunah Cho;Sehyun Park;Kyeongho Jeon;Yohan Yoon;Yoonjeong Yoo;Younghyun Cho;Jinho Cho
    • Journal of Animal Science and Technology
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    • v.65 no.3
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    • pp.611-626
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    • 2023
  • Escherichia coli (E. coli) and Salmonella enterica (SE) infections in pigs are major source associated with enteric disease such as post weaning diarrhea. The aim of this study was to investigate the effects of Pediococcus pentosaceus in weaned piglets challenged with pathogen bacteria. In Experiment.1 90 weaned piglets with initial body weights of 8.53 ± 0.34 kg were assigned to 15 treatments for 2 weeks. The experiments were conducted two trials in a 2 × 5 factorial arrangement of treatments consisting of two levels of challenge (challenge and non-challenge) with E. coli and SE, respectively and five levels of probiotics (Control, Lactobacillus plantarum [LA], Pediococcus pentosaceus SMFM2016-WK1 [38W], Pediococcus acidilactici K [PK], Lactobacillus reuteri PF30 [PF30]). In Experiment.2 a total of 30 weaned pigs (initial body weight of 9.84 ± 0.85 kg) were used in 4 weeks experiment. Pigs were allocated to 5 groups in a randomized complete way with 2 pens per group and 3 pigs per pen. Supplementation of LA and 38W improved (p < 0.05) growth performance, intestinal pathogen bacteria count, fecal noxious odor and diarrhea incidence. In conclusion, supplementation of 38W strains isolated from white kimchi can act as probiotics by inhibiting E. coli and SE.

Evaluation of Comprehensive Effects of Methanol Extracts of Coptidis rhizoma against Several Oral Pathogenic Bacteria (황련 메탄올 추출물의 주요 구강 병원성 세균에 대한 포괄적 활성 평가)

  • Chae Hyeon Seo;Youngcheon Song;Dongsool Yim;Sungsook Choi
    • Korean Journal of Pharmacognosy
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    • v.54 no.1
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    • pp.27-37
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    • 2023
  • This research was conducted to investigate the comprehensive effects of methanol extract of Coptidis rhizoma (MECR) against oral pathogen. We studied the antibacterial, anti-biofilm, anti-gingipain and anti-inflammatory activity of MECR. The minimum bactericidal concentration (MBC) of MECR was 100 ㎍/mL against several oral pathogens. The formation of biofilm of Streptococcus mutans was reduced to 8.93~24.12% in the presence of 25 ㎍/mL of MECR. The gingipain activity of Porphyromonas gingivalis were reduced to 3.91~6.23% in case of Kgp and 5.73~7.78% in case of Rgp in the presence of 10 mg/mL of MECR. The expression of fadA mRNA, virulence factor of Fusobacterium nucleatum (F. nucleatum) was 3 folds decreased in the presence of 25 ㎍/mL of MECR. In case of YD-38 cells challenged with F. nucleatum, RQ values of IL-8 and IL-6 were reduced about 12 folds and 5.45 folds in the presence of 2 ㎍/mL of MECR. In case of RAW 264.7 murine cell challenged with F. nucleatum, RQ values of IL-1β and IL-6 were 2.52 folds and 2.55 folds reduced in the presences of 2 ㎍/mL of MECR. Conclusively, MECR showed potent antibacterial and anti-inflammatory effects against oral pathogenic bacteria.

The Effect of Participation Degree in Sports for all of People with Physical Disabilities on Positive Psychological Capital(PPC) (지체장애인의 생활체육 참여정도가 긍정심리자본(PPC)에 미치는 영향)

  • Kim, Dae-Kyung;Park, Jin-Woo;Kim, Hye-Min;Lee, Hyun-Su
    • 한국체육학회지인문사회과학편
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    • v.54 no.5
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    • pp.867-876
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    • 2015
  • This study was intended to closely examine an effect that the level of physically challenged person's participation in community sports had on positive psychological capital. In order to accomplish the purpose of study, data on 212 physically challenged persons who lived in B city and participated in community sports were analyzed. Korean version of positive psychological capital created by Taehong Lim (2014) through the reconstruction of scales developed by Luthans, Youssef and Avolio(2007) and Sangwan Jeon and Jonghun Yang's (2009) level of participation in community sports was reconstructed through modification·improvement as measurement instrument. An exploratory factor analysis, reliability test, paired difference test, and multiple regression analysis was carried out by using SPSS 18.0 program for data processing. First, It was shown that there was a significant difference in positive psychological capital according to gender, age, and disability grade among physically challenged persons' socio-demographic characteristics. Second, it was shown that, among sub-variables (period, frequency and intensity) of level of physically challenged persons' participation in community sports, the frequency of participation and the intensity of participation had a significant effect on self efficacy. On the other hand, it was shown that the period of participation didn't have a significant effect. Third, it was shown that the frequency of participation had a significant effect on optimism. On the other hand, it was shown that the period of participation and the intensity of participation didn't have a significant effect. Fourth, it was shown that the frequency of participation and the intensity of participation had a significant effect on hope. On the other hand, it was shown that no significant effect was produced on the period of participation. Fifth, it was shown that the frequency of participation had a significant effect on resilience. On the other hand, it was shown that no significant effect was produced on the period of participation and the intensity of participation. Sixth, it was shown that the frequency of participation and the intensity of participation had a significant effect on positive psychological capital. And it was shown that no significant effect was produced on the period of participation.

Critical Review on Functionalistic Perspective in Family Study it is Limitation and Alternatives (가족연구의 이론적 시각-기능주의 가족이론의 한계와 대안적 논의)

  • 배선희
    • Journal of Families and Better Life
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    • v.11 no.2
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    • pp.147-155
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    • 1993
  • This study attemps to rethink assumption that the family can be 'a heaven' to everyone in a harsh world through theoretical review Functionalists insist that people feel emotional secure through family life. However this pers-pective sees only the one side of the family experience ignoring the other side of its tension and conflicts in the family. From marxist perspective the family experiences may not be the same among different social classes due to their economic inequality, It might be that middle class family is more likely to experiences emotional secure than any other social class. Feminists have challenged prevalent assumptions about the family. They see that women are oppressed by the family. These results mean that marxist and feminist perspectives compensate for the limitation of functionalism. I'd like to propose that marxist and feminist perspectives can be used framewrok for the family study.

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A Study on The Utility Estimation about Employment of The Disabled (AHP를 이용한 장애인고용의 효용성평가 연구)

  • Na, Hea-Sook
    • Journal of the Korea Safety Management & Science
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    • v.10 no.2
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    • pp.225-235
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    • 2008
  • It is expected that the change of industrial structure of Knowledge based economy, and service based economy would affect on economic life of physically-challenged person with no exceptions. There have been some former studies which have been misunderstood the employment of disabled due to the declining employment of the disabled and prejudice to the disabled based on biased perspective and public opinion. This study have analyzed the employment conditions of the ordinary workers and disabled workers out of those prejudices and biased opinions. Wage, economic activity ratio, age, educational background and industry those 5 parameters are brought for analyzing the two comparison group. Each parameter have compared based on the statistical data of ordinary workers and disabled workers for past 7 years. Weight between each parameter have been drawn by collecting the experts' opinion using AHP(Analytic Hierarchy Process), and utility of employment of two comparison groups have been estimated through progress inclination of each parameter. Through the estimated outcome, present condition and controversial issues and way of improvement of domestic employment of ordinary workers and the disabled is mentioned.

Sensory Integration Therapy Camp(the Challenging Children) Report (대한 감각통합치료학회 주최 제1회 감각통합치료캠프(도전하는 아이들) 보고)

  • Ji, Seok-Yeon;Kim, Kyeong-Mi
    • The Journal of Korean Academy of Sensory Integration
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    • v.1 no.1
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    • pp.81-86
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    • 2003
  • To make up extended and intensive sensory integration program, Korean Society of Sensory Integration Therapist(KSSIT) planned and practiced sensory integration camp. Camp were held during 5 days and 7 children with sensory integrative dysfunction were participated in the camp. COPM, Sensory profile, STEP-SI and interview were used for deciding the therapy goals. For preparing the camp, therapists did seminars, discussion and get advices form specialists in US and Japan. Through the camp, as the theme, not only children and parents got the chance of challenging but also therapists challenged by themselves. For this camp KSSIT expected to build up more effective sensory integrative program and research.

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Effect of Juglandis Semen Aqua-acupuncture and Acupuncture on the Allergic Response (호도약침이 알레르기에 미치는 영향)

  • Lee Zoo Eun;Lee Tae Yong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.1
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    • pp.123-129
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    • 2003
  • Experimental studies were done to research the dinical effects of Juglandis Semen aqua-acupuncture and acupuncture(BL 13) on the anti-allergic response. anaphylaxis provoked by the compound 48/80, delayed type hypersensitivity response to picryl chloride and SASC and inflammation response to egg albumin. The following results have been obtained: Juglandis Semen aqua-acupuncture and acupuncture(BL13) group were increased the survival rate in compound48/80 induced systemic anaphylactic reaction. Picryl chloride induced contact dermatitis and delayed type hypersensitivity in SRBC challenged mouse were significantly decreased in Juglandis Semen aqua-acupuncture and acupuncture (BL13) group. Inflammation response - WBC, CRP and Nitric Oxide in egg albumin induced allergic rat were significantly decreased in Juglandis Semen aqua-acupuncture and acupuncture(BL13) group. According to the above results, Semen aqua-acupuncture and acupuncture(BL13) both depress the allergy reaction.

Effects of Ethanol and Saccharin on the Immune Response in Rats (랏트에 있어서 에탄올과 삭카린이 면역반응에 미치는 영향)

  • 안영근;김주영;김정훈;염정열
    • Environmental Analysis Health and Toxicology
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    • v.2 no.1_2
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    • pp.33-42
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    • 1987
  • Experiments were performed to investigate effects of ethanol and saccharin on the immune system in rats. 4% ethanol and 0.02, 0.20, 2.00% saccharin solution in 4% ethanol were provided ad libitum by tap water for 4 weeks. Rats were sensitized and challenged with sheep red blood cells (S-RBC). Immune responses were evaluated by relative immuno organ weight, antibody production, Arthus reaction, delayed type hypersensitivity, and rosette forming cell. Ethanol exposure decreased thymus weight and delayed type hypersensitivity. A combined solution of ethanol and saccharin decreased water intake, growth rate, spleen weight, thymus weight, humoral and cellular immune response. Especially, a 2% saccharin solution in 4% ethanol very significantly suppressed cellular immunity.

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Effect of Ethanol on the Immunotoxicity of Ampicillin in Mice (Ampicillin의 면역독성에 미치는 Ethanol의 영향)

  • 안영근;김정훈;나헌진
    • Environmental Analysis Health and Toxicology
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    • v.3 no.1_2
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    • pp.55-64
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    • 1988
  • Experiments were performed on mice to investigate the influences of ampicillin and ethanol on the immune response. Ampicillin was injected intraperitoneally and ethanol was administered in the drinking water. Mice were sensitized and challenged with sheep red blood cells. Immune responses were evaluated by humoral immunity, cellular immunity, peripheral circulating white blood cell and phagocyte activity. 1. The combined administration of ampicillin and ethanol as compared to ampicillin had not influence on the weight of spleen, but increased the weight of thymus. 2. Humoral immune response was slightly reduced by ampicillin. Especially, the combined administration of ampicillin and ethanol significantly reduced hemclysin production. 3. Cellural immune response was reduced by ampicillin. The combine administration of ampicillin and ethanol significantly reduced cellural immune response. 4. Peripheral circulating white blood cell was reduced by the combined administration of ampicillin and ethanol as compared to ampicillin. 5. The combined administration of ampicillin and ethanol as compared to ampicillin had not influence on the phagocyte activity.

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Effect of Ginseng petroleum Ether Fraction on the Immunotoxicity of Cadmium in Mice (I) (마우스에 있어서 카드뮴의 면역독성에 미치는 인삼석유 Ether 분획의 영향( I ))

  • 안영근;김정훈;이상근;황갑수
    • Environmental Analysis Health and Toxicology
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    • v.3 no.1_2
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    • pp.43-54
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    • 1988
  • Experiment was performed to investigate the immunotoxicity of cadmium administered orally and the effect of ginseng petroleum ether fraction on it. Mice were given 3, 30, or 300 ppm cadmium as cadmium chloride orally in the drinking water and injection of ginseng petroleum ether fraction intraperitoneally for 4 weeks. Mice were sensitized and challenged with sheep red blood cells (S-RBC). Humoral immune response was evaluated by antibody production and Arthus reaction. Body weight gain, spleen weight, thymus weight, and liver weight were also measured. In the present study, cadmium generally suppressed the humoral immunity. There was decrease in the rate of body weight gain and liver weight to body weight by cadmium-administration. Ginseng petroleum ether fraction showed restoring effect, to some extent, on the decrease in PFC and in the rate of liver weight to body weight by cadmium-administration. But it more suppressed Arthus reaction.

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