Serum concentrations of α2-macroglobulin, α1-antitrypsin, and C-reactive protein in dogs with suspected acute pancreatitis |
Park, Soyoung
(Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University)
Kim, Hakhyun (Laboratory of Veterinary Internal Medicine and Neuroendocrinology, College of Veterinary Medicine, Chungbuk National University) Kang, Ji-Houn (Laboratory of Veterinary Internal Medicine and Neuroendocrinology, College of Veterinary Medicine, Chungbuk National University) Kang, Byeong-Teck (Laboratory of Veterinary Dermatology and Neurology, College of Veterinary Medicine, Chungbuk National University) Yang, Mhan-Pyo (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University) |
1 | Caspi D, Snel FW, Batt RM, Bennett D, Rutteman GR, Hartman EG, Baltz ML, Gruys E, Pepys MB. C-reactive protein in dogs. Am J Vet Res 1987;48:919-921. |
2 | Puolakkainen P, Valtonen V, Paananen A, Schroder T. Creactive protein (CRP) and serum phospholipase A2 in the assessment of the severity of acute pancreatitis. Gut 1987;28:764-771. DOI |
3 | Rau B, Steinbach G, Baumgart K, Gansauge F, Grunert A, Beger HG. Serum amyloid A versus C-reactive protein in acute pancreatitis: clinical value of an alternative acute-phase reactant. Crit Care Med 2000;28:736-742. DOI |
4 | Bassi D, Kollias N, Fernandez-del Castillo C, Foitzik T, Warshaw AL, Rattner DW. Impairment of pancreatic microcirculation correlates with the severity of acute experimental pancreatitis. J Am Coll Surg 1994;179:257-263. |
5 | Koj A, Kurdowska A, Magielska-Zero D, Rokita H, Sipe JD, Dayer JM, Demczuk S, Gauldie J. Limited effects of recombinant human and murine interleukin 1 and tumour necrosis factor on production of acute phase proteins by cultured rat hepatocytes. Biochem Int 1987;14:553-560. |
6 | Ruaux CG, Atwell RB. Levels of total alpha-macroglobulin and trypsin-like immunoreactivity are poor indicators of clinical severity in spontaneous canine acute pancreatitis. Res Vet Sci 1999;67:83-87. DOI |
7 | Murtaugh RJ, Jacobs RM. Serum antiprotease concentrations in dogs with spontaneous and experimentally induced acute pancreatitis. Am J Vet Res 1985;46:80-83. |
8 | Goodman AJ, Bird NC, Johnson AG. Antiprotease capacity in acute pancreatitis. Br J Surg 1986;73:796-798. DOI |
9 | Andus T, Geiger T, Hirano T, Kishimoto T, Tran-Thi TA, Decker K, Heinrich PC. Regulation of synthesis and secretion of major rat acute-phase proteins by recombinant human interleukin-6 (BSF-2/IL-6) in hepatocyte primary cultures. Eur J Biochem 1988;173:287-293. DOI |
10 | Lobo SM, Lobo FR, Bota DP, Lopes-Ferreira F, Soliman HM, Melot C, Vincent JL. C-reactive protein levels correlate with mortality and organ failure in critically ill patients. Chest 2003;123:2043-2049. DOI |
11 | Mansfield C. Pathophysiology of acute pancreatitis: potential application from experimental models and human medicine to dogs. J Vet Intern Med 2012;26:875-887. DOI |
12 | Holm JL, Rozanski EA, Freeman LM, Webster CRL. Creactive protein concentrations in canine acute pancreatitis. J Vet Emerg Crit Care (San Antonio) 2004;14:183-186. DOI |
13 | Papa K, Mathe A, Abonyi-Toth Z, Sterczer A, Psader R, Hetyey C, Vajdovich P, Voros K. Occurrence, clinical features and outcome of canine pancreatitis (80 cases). Acta Vet Hung 2011;59:37-52. DOI |
14 | Gauldie J, Richards C, Harnish D, Lansdorp P, Baumann H. Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc Natl Acad Sci U S A 1987;84:7251-7255. DOI |
15 | Steiner JM. Canine pancreatic disease. In: Ettinger SJ, Feldman EC (eds.). Textbook of Veterinary Internal Medicine. 7th ed. pp. 1695-1704, WB Saunders Company, Philadelphia, 2010. |
16 | Ernster L. Biochemistry of reoxygenation injury. Crit Care Med 1988;16:947-953. DOI |
17 | Dominguez-Munoz JE, Carballo F, Garcia MJ, Miguel de Diego J, Gea F, Yanguela J, de la Morena J. Monitoring of serum proteinase--antiproteinase balance and systemic inflammatory response in prognostic evaluation of acute pancreatitis. Results of a prospective multicenter study. Dig Dis Sci 1993;38:507-513. DOI |
18 | Newman S, Steiner J, Woosley K, Barton L, Ruaux C, Williams D. Localization of pancreatic inflammation and necrosis in dogs. J Vet Intern Med 2004;18:488-493. DOI |
19 | Geokas MC, Van Lancker JL, Kadell BM, Machleder HI. Acute pancreatitis. Ann Intern Med 1972;76:105-117. DOI |
20 | Mayer AD, McMahon MJ, Bowen M, Cooper EH. C reactive protein: an aid to assessment and monitoring of acute pancreatitis. J Clin Pathol 1984;37:207-211. DOI |
21 | Petersen CM. Alpha 2-macroglobulin and pregnancy zone protein. Serum levels, alpha 2-macroglobulin receptors, cellular synthesis and aspects of function in relation to immunology. Dan Med Bull 1993;40:409-446. |
22 | Balldin G, Laurell CB, Ohlsson K. Increased catabolism of alpha-Macroglobulins after intravenous infusion of trypsinalpha1- antitrypsin complexes in dogs. Hoppe Seylers Z Physiol Chem 1978;359:699-708. |
23 | Xenoulis PG, Steiner JM. Canine and feline pancreatic lipase immunoreactivity. Vet Clin Pathol 2012;41:312-324. DOI |
24 | Ohlsson K. Elimination of 125-I-trypsin alpha-macroglobulin complexes from blood by reticuloendothelial cells in dogs. Acta Physiol Scand 1971;81:269-272. DOI |
25 | Kim DI, Kim H, Son P, Kang JH, Kang BT, Yang MP. Serum 25-hydroxyvitamin D concentrations in dogs with suspected acute pancreatitis. J Vet Med Sci 2017;79:1366-1373. DOI |
26 | Mansfield C. Acute pancreatitis in dogs: advances in understanding, diagnostics, and treatment. Top Companion Anim Med 2012;27:123-132. DOI |
27 | de Beaux AC, Ross JA, Maingay JP, Fearon KC, Carter DC. Proinflammatory cytokine release by peripheral blood mononuclear cells from patients with acute pancreatitis. Br J Surg 1996;83:1071-1075. DOI |
28 | Paek J, Kang JH, Kim HS, Lee I, Seo KW, Yang MP. Serum adipokine concentrations in dogs with acute pancreatitis. J Vet Intern Med 2014;28:1760-1769. DOI |
29 | Wilson C, Heads A, Shenkin A, Imrie CW. C-reactive protein, antiproteases and complement factors as objective markers of severity in acute pancreatitis. Br J Surg 1989;76:177-181. DOI |
30 | Lasson A, Ohlsson K. Protease inhibitors in acute human pancreatitis. Correlation between biochemical changes and clinical course. Scand J Gastroenterol 1984;19:779-786. DOI |
31 | Banks RE, Evans SW, Alexander D, Van Leuven F, Whicher JT, McMahon MJ. Alpha 2 macroglobulin state in acute pancreatitis. Raised values of alpha 2 macroglobulin-protease complexes in severe and mild attacks. Gut 1991;32:430-434. DOI |
32 | Burton SA, Honor DJ, Mackenzie AL, Eckersall PD, Markham RJ, Horney BS. C-reactive protein concentration in dogs with inflammatory leukograms. Am J Vet Res 1994;55:613-618. |
33 | McMahon MJ, Bowen M, Mayer AD, Cooper EH. Relation of alpha 2-macroglobulin and other antiproteases to the clinical features of acute pancreatitis. Am J Surg 1984;147:164-170. DOI |
34 | Hedstrom J, Sainio V, Kemppainen E, Haapiainen R, Kivilaakso E, Schroder T, Leinonen J, Stenman UH. Serum complex of trypsin 2 and alpha 1 antitrypsin as diagnostic and prognostic marker of acute pancreatitis: clinical study in consecutive patients. BMJ 1996;313:333-337. DOI |
35 | Rinderknecht H. Fatal pancreatitis, a consequence of excessive leukocyte stimulation? Int J Pancreatol 1988;3:105-112. DOI |
36 | Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response. Biochem J 1990;265:621-636. DOI |
37 | Geiger T, Andus T, Klapproth J, Hirano T, Kishimoto T, Heinrich PC. Induction of rat acute-phase proteins by interleukin 6 in vivo. Eur J Immunol 1988;18:717-721. DOI |
38 | Ballou SP, Lozanski G. Induction of inflammatory cytokine release from cultured human monocytes by C-reactive protein. Cytokine 1992;4:361-368. DOI |
![]() |