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http://dx.doi.org/10.14405/kjvr.2018.58.3.143

Genetic variations in open reading frame 2 gene of porcine circovirus type 2 isolated in Korea during 2016-2017  

Kim, Kiju (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
Choi, Jong-Young (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
Lyoo, Kwang-Soo (Korea Zoonosis Research Institute, Chonbuk National University)
Hahn, Tae-Wook (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
Publication Information
Korean Journal of Veterinary Research / v.58, no.3, 2018 , pp. 143-146 More about this Journal
Abstract
The capsid protein of porcine circovirus type 2 (PCV2) encoded by open reading frame 2 (ORF2) is important for neutralizing activity against PCV2 infection. This study investigated the heterogeneity of the ORF2 gene of PCV2 isolated in Korea during 2016-2017. The results revealed that PCV2d is currently the predominant genotype. Moreover, comparison of ORF2 from 17 PCV2 isolates revealed 88.3-100% homology at the nucleotide (deduced amino acid 86.3-100%) level. Interestingly, 61.5% (8/13) of the PCV2d isolates had glycine at position 210. These data provide a useful information for PCV2 epidemiology in Korea.
Keywords
capsid proteins; genetic variation; phylogenetic analysis; porcine circovirus type 2;
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