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http://dx.doi.org/10.14405/kjvr.2011.51.2.117

Comparison of tuberculin skin test with Interferon-γ assay for the diagnosis of bovine tuberculosis in Korean cattle  

Shin, Seung Won (College of Veterinary Medicine and BK21 for Veterinary Science, Seoul National University)
Shin, Min Kyoung (College of Veterinary Medicine and BK21 for Veterinary Science, Seoul National University)
Cha, Seung Bin (College of Veterinary Medicine and BK21 for Veterinary Science, Seoul National University)
Woo, Jong Tae (Gyeonggido Veterinary Service)
Lee, Sung Mo (Incheon Metropolitan City Institute of Health & Environment)
Ku, Bok Kyung (Bacterial Disease Division, Department of Animal and Plant Health Research, Animal, Plant and Fisheries Quarantine and Inspection Agency)
Cho, Yun Sang (Bacterial Disease Division, Department of Animal and Plant Health Research, Animal, Plant and Fisheries Quarantine and Inspection Agency)
Jung, Suk Chan (Bacterial Disease Division, Department of Animal and Plant Health Research, Animal, Plant and Fisheries Quarantine and Inspection Agency)
Yoo, Han Sang (College of Veterinary Medicine and BK21 for Veterinary Science, Seoul National University)
Publication Information
Korean Journal of Veterinary Research / v.51, no.2, 2011 , pp. 117-122 More about this Journal
Abstract
Bovine tuberculosis (bTB), caused primarily by Mycobacterium bovis, continues to exert an economic loss, even in countries with active control measures, and is one of zoonotic diseases enable to be transmitted to human. The control and eradication of bTB are mainly based on a test and slaughter policy and/or abattoir surveillance. Various factors including limitation of diagnostic tests have been considered as major constraints to eradication. Single intradermal test (SIT) is the official diagnostic test. New diagnostic methods are needed to be developed, because of limitations of the test. In the present study SIT was compared with single intradermal comparative cervical test (SICCT) and interferon (IFN)-${\gamma}$ assay. There was very low correlation between SIT and SICCT. However, high correlation was shown between SIT and IFN-${\gamma}$ assay while no correlation was observed between SICCT and IFN-${\gamma}$ assay. Therefore, our results suggest the possibility of replacement of SIT with IFN-${\gamma}$ assay for the diagnosis of bovine tuberculosis.
Keywords
bovine tuberculosis; IFN-${\gamma}$ assay; SICCT; SIT;
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Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By SCOPUS : 0
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