Phenidone, a dual inhibitor of cyclooxygenase and lipoxygenase, inhibits carbon tetrachloride-induced acute liver injury in rats |
Choi, Hyuop
(College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University)
Joeng, Donghwan (College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University) Jung, Bae-Dong (College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University) Shin, Taekyun (College of Veterinary Medicine, Jeju National University) Wie, Myung-Bok (College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University) |
1 | Halliwell B, Gutteridge JM. The importance of free radicals and catalytic metal ions in human diseases. Mol Aspects Med 1985, 8, 89-193. DOI ScienceOn |
2 | Horrillo R, Planaguma A, Gonzalez-Periz A, Ferre N, Titos E, Miquel R, Lopez-Parra M, Masferrer JL, Arroyo V, Claria J. Comparative protection against liver inflammation and fibrosis by a selective cyclooxygenase-2 inhibitor and a nonredox-type 5-lipoxygenase inhibitor. J Pharmacol Exp Ther 2007, 323, 778-786. DOI ScienceOn |
3 | Kawada N, Mizoguchi Y, Kobayashi K, Yamamoto S, Morisawa S. Arachidonic acid metabolites in carbon tetrachloride-induced liver injury. Gastroenterol Jpn 1990, 25, 363-368. DOI ScienceOn |
4 | Kim HC, Jhoo WK, Bing G, Shin EJ, Wie MB, Kim WK, Ko KH. Phenidone prevents kainate-induced neurotoxicity via antioxidant mechanisms. Brain Res 2000, 874, 15-23. DOI ScienceOn |
5 | McCay PB, Lai EK, Poyer JL, DuBose CM, Janzen EG. Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism: observation of lipid radicals in vivo and in vitro. J Biol Chem 1984, 259, 2135-2143. |
6 | Moon C, Ahn M, Wie MB, Kim HM, Koh CS, Hong SC, Kim MD, Tanuma N, Matsumoto Y, Shin T. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res 2005, 1035, 206-210. DOI ScienceOn |
7 | Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95, 351-358. DOI ScienceOn |
8 | Perez Tamayo R. Is cirrhosis of the liver experimentally produced by and adequate model of human cirrhosis? Hepatology 1983, 3, 112-120. |
9 | Sen T, Dhara AK, Bhattacharjee S, Pal S, Nag Chaudhuri AK. Antioxidant activity of the methanol fraction of Pluchea indica root extract. Phytother Res 2002, 16, 331-335. DOI ScienceOn |
10 | Wie MB, Cho YJ, Jhoo WK, Kim HC. Phenidone attenuates oxygen/glucose deprivation-induced neurotoxicity by antioxidant and antiapoptotic action in mouse cortical cultures. Neurosci Lett 1999, 272, 91-94. DOI ScienceOn |