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Toxoplasmic meningoencephalitis in a stray cat in Korea  

Kim, Ha-Young (Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service)
Bae, You-Chan (Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service)
Woo, Gye-Hyeong (Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service)
Byun, Jae-Won (Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service)
Jung, Byeong-Yeal (Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service)
Park, Jung-Won (Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service)
Chae, Hee-Sun (Research Institute of Public Health & Environment)
Choi, Jae-Yong (Korean Veterinary Medical Association)
Nakayama, Hiroyuki (Graduate School of Agricultural and Life Sciences, The University of Tokyo)
Hwang, Eui Kyung (College of Life Science and Natural Resources, Sangji University)
Joo, Yi-Seok (Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service)
Lee, O-Soo (Animal Disease Diagnostic Center, National Veterinary Research and Quarantine Service)
Publication Information
Korean Journal of Veterinary Research / v.49, no.4, 2009 , pp. 291-295 More about this Journal
Abstract
A dead stray cat was necropsied for zoonotic feline disease monitoring. Grossly, there were no specific lesions. Major microscopic lesions included lymphocytic meningoencephalitis, malacia, and tissue cysts in the cerebral and cerebellar cortex. The size and shape of tissue cysts were identical to those of Apicomplexa including Toxoplasma (T.) gondii. Bradyzoites in the tissue cyst were strongly positive for T. gondii by immunohistochemistry. Electron microscopy revealed that bradyzoites within the tissue cyst were similar to the morphological features of T. gondii. Fresh tissue samples were examined by a polymerase chain reaction assay and resulted in a specific band of T. gondii only in the brain. Based on the results, this case was diagnosed as toxoplasmosis. This is the first case of toxoplasmic meningoencephalitis in a cat in Korea.
Keywords
bradyzoite; cat; meningoencephalitis; tissue cysts; toxoplasmosis;
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