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Immunological relationships of FMD vaccine strain and Asia1 field isolate from East Asia  

Park, Jong-Hyeon (Foreign Animal Disease Division, National Veterinary Research and Quarantine Service)
Ko, Young-Joon (Foreign Animal Disease Division, National Veterinary Research and Quarantine Service)
Kim, Su-Mi (Foreign Animal Disease Division, National Veterinary Research and Quarantine Service)
Lee, Hyang-Sim (Foreign Animal Disease Division, National Veterinary Research and Quarantine Service)
Lee, Kwang-Nyeong (Foreign Animal Disease Division, National Veterinary Research and Quarantine Service)
Cho, In-Soo (Foreign Animal Disease Division, National Veterinary Research and Quarantine Service)
Publication Information
Korean Journal of Veterinary Research / v.49, no.3, 2009 , pp. 221-229 More about this Journal
Abstract
Foot-and-mouth disease (FMD) is the most contagious disease of mammals. The use of inactivated vaccine can be chosen to prevent or control FMD. However, vaccination against one serotype of FMDV doses not cross-protect against other serotypes and may not protect fully against some strains of the same serotype. Appropriate selection of vaccine strain is an important element in the control of FMD. The immunity of vaccine antigens should be matched against newly circulating viruses. The phylogenetic analysis of serotype Asia1 reported from China, Mongolia, North Korea and Russia since 2005 shows that they are all classified into genetic group V, but the strain, Asia1/Shamir (ISR/89) which have been used as a vaccine strain in Korea, is clustered into different genetic group. So, in this study the serological relationship between the isolate (Asia1/MOG/05; MOG) and the Shamir strain was determined by ELISA and virus neutralization test. Even though the matching value of the virus (MOG) against the vaccinated sera in target animals was not so high, the vaccinated animals elicited antibodies enough for protection after vaccinated once or twice. Conclusively, we suggest that the vaccine containing Asia1/Shamir antigen could protect the genetic group V strains circulating in East Asia currently if vaccinated twice or the more.
Keywords
ELISA; FMD vaccine; neutralization; vaccine matching;
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1 Bachrach HL. Foot-and-mouth disease. Annu Rev Microbiol 1968, 22, 201-244   DOI   PUBMED   ScienceOn
2 Knowles NJ. Update on the world situation in relation to FMD. In: OIE regional coordinational unit (ed.). Report of 13th Meeting of the OIE Sub-commission for Southeast Asia. Appendix 1. p. 11, OIE, Bankkok, 2007
3 Brehm KE, Kumar N, Thulke HH, Haas B. High potency vaccines induce protection against heterologous challenge with foot-and-mouth disease virus. Vaccine 2008, 26, 1681-1687   DOI   ScienceOn
4 Park JH, Park JY, Kim YJ, Oem JK, Lee KN, Kye SJ, Joo YS. Vaccination as a control measure during the outbreak of foot-and-mouth disease in 2000 in Korea. Dev Biol (Basel) 2004, 119, 63-70
5 Oh YI. Current knowledge of foot-and-mouth disease. Kor J Vet Publ Hlth 2008, 32, 237-243
6 Sur JH, Shin JH, Loubroth J, Yeh M, Ku BK, Choi KS, Kweon BJ, Sohn HJ, Ko YJ, Choi CU, Kwon CH, Kim JY, An SH, Kim KS, Moon OK, Kim JH, Choi SH, Lee HG, Hwang EK, Kim SB, Kang SS, Kim OK. In Vivo characterization and transmission of Korean foot-and-mouth disease virus (FMDV). Korea J Vet Res 2000, 40, 719-727
7 Ko YJ, Jeoung HY, Lee HS, Chang BS, Hong SM, Heo EJ, Lee KN, Joo HD, Kim SM, Park JH, Kweon CH. A recombinant protein-based ELISA for detecting antibodies to foot-and-mouth disease virus serotype Asia 1. J Virol Methods 2009, 159, 112-118   DOI   ScienceOn
8 Park JH, Lee KN, Kim SM, Ko YJ, Lee HS, Kweon CH, Yang CB. Molecular epidemiological analysis and recent distribution of foot-and-mouth disease in the world. Kor J Vet Publ Hlth 2008, 32, 61-68
9 Kitching P, Hammond J, Jeggo M, Charleston B, Paton D, Rodriguez L, Heckert R. Global FMD control-Is it an option? Vaccine 2007, 25, 5660-5664   DOI   ScienceOn
10 Park JH, Lee KN, Kim SM, Ko YJ, Lee HS, Heo EJ, Joo YS, Kweon CH, Yang CB. The present and future of foot-and-mouth disease emergency vaccine. Kor J Vet Publ Hlth 2008, 32, 173-181
11 Office International de Epizooties (OIE). Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2008: Mammals, Birds and Bees. 6th ed. pp 190-216, OIE, Paris, 2008
12 Hedger RS. Observations on the carrier state and related antibody titres during an outbreak of foot-andmouth disease. J Hyg (Lond) 1970, 68, 53-60   DOI   ScienceOn
13 Paton DJ, Valarcher JF, Bergmann I, Matlho OG, Zakharov VM, Palma EL, Thomson GR. Selection of foot and mouth disease vaccine strains-a reviews. Rev Sci Tech 2005, 24, 981-993   DOI   PUBMED
14 Meloen RH. Localisation on foot-and-mouth disease virus (FMDV) of an antigenic deficiency induced by passage in BHK cells. Arch Virol 1976, 51, 299-306   DOI   PUBMED   ScienceOn
15 Hammond JM, King DP, Knowles NJ, Wadsworth J, Swabey KG, Statham B, Li Y, Keel P, Hamblin P, Hutchings GH, Reid SM, Ebert K, Stirling JM, Ferris NP, Chisholm C, Byrom E, Paton DJ. Update on the world situation in relation to FMD. In: OIE regional coordinational unit (ed.). Report of 15th Meeting of the OIE Sub-commission for Southeast Asia. Appendix 1. OIE, Bankkok, 2009
16 Mahapatra M, Aggarwal N, Cox S, Statham RJ, Knowles NJ, Barnett PV, Paton DJ. Evaluation of a monoclonal antibody-based approach for the selection of foot-and-mouth disease (FMD) vaccine strains. Vet Microbiol 2008, 126, 40-50   DOI   PUBMED   ScienceOn
17 Bolwell C, Brown AL, Barnett PV, Campbell RO, Clarke BE, Parry NR, Ouldridge EJ, Brown F, Rowlands DJ. Host cell selection of antigenic variants of foot-and-mouth disease virus. J Gen Virol 1989, 70, 45-57   DOI   ScienceOn
18 Knowles NJ, Valarcher JF, Zakharov VM, Scherbakov AV, Zhang Z, Shang YJ, Liu ZX, Liu XT, Sanyal A, Hemadri D, Tosh C, Rasool TJ, Rodriguez LL, Backham TR, Linchongsubongkoch W, Ferris NP, Roeder PL, Paton DJ. Recent molecular epidemiology of foot and mouth disease virus Asia 1. In: Food and agriculture organization of the united nations (FAO), European commission for the control of foot-and-mouth disease (EUFMD) (eds.). Report of the Session of the Research Group of the Standing Technical Committee of EUFMD. pp 97-104,OIE, Rome, 2006懟╰櫟╰苟╰裟╰諟╰闟╰ꃟ╰ꛟ╰돟╰뗟╰럟╰?╰?╰?╰╰Ԁጀᄀ氀਀鐀嬀⼀Ḁ਀琅ꘀ਀̀㼀␀鸍ЀĀȀȀࠀᜀԀĀ਀਀Ԁ਀ĀĀ℀ĀĀ᐀਀āāāāāāāāāāāāāāĀĀ ⢨잖⨀墨잖⨀袨잖⨀잖⨀エ잖⨀
19 Oem JK, Park JH, Lee KN, Kim YJ, Kye SJ, Park JY, Song HJ. Characterization of recombinant footand- mouth disease virus pentamer-like structures expressed by baculovirus and their use as diagnostic antigens in a blocking ELISA. Vaccine 2007, 25, 4112- 4121   DOI   ScienceOn
20 Park JH, Lee KN. Kim SM, Ko YJ, Lee HS, Heo EJ, Kweon CH, Yang CB. Role of persistent infection in the transmission of foot-and-mouth disease. Kor J Vet Publ Hlth 2008, 32, 189-197