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Survey of extended-spectrum β-Lactamase (ESBL) in pathogenic Escherichia coli isolated from poultry in Korea  

Sung, Myung-Suk (College of Veterinary Medicine, Kyungpook National University)
Kim, Jin-Hyun (College of Veterinary Medicine, Kyungpook National University)
Cho, Jae-Keun (Health & Environmental Research Institute)
Seol, Sung-Yong (Kyungpook National University School of Medicine)
Kim, Ki-Seuk (College of Veterinary Medicine, Kyungpook National University)
Publication Information
Korean Journal of Veterinary Research / v.48, no.3, 2008 , pp. 259-265 More about this Journal
Abstract
This study was conducted to investigate incidence of extended-spectrum ${\beta}$-lactamase (ESBL) producing strains and characteristics of ESBL gene in pathogenic Escherichia coli isolated from poultry during the period from April 2003 to December 2005 in Korea. Among 203 isolates, 4 isolates (3 from broilers and 1 from layer) were confirmed as ESBL producing strains by double disk synergy test, polymerase chain reaction and sequencing for ${\beta}$-lactamase genes. $bla_{CTX-M-15}$ and $bla_{CMY-2}$ were detected in these 4 isolates and were transferred to recipient by conjugation, respectively. Also, these ESBL producing strains were associated with multiple drug resistance. In conclusion, these results exhibit incidence of CTX-M and CMY-2 ${\beta}$-lactamase in pathogenic E coli from poultry in Korea, and clinically important meaning in human. And they also suggest the needs for rapid and broad surveillance to monitor ESBL genes and R plasmid transferring resistant gene in poultry.
Keywords
ESBL genes; extended-spectrum ${\beta}$-Lactamase (ESBL); Korea; pathogenic Escherichia coli; poultry;
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Times Cited By KSCI : 2  (Citation Analysis)
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