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Pneumocystis carinii pneumonia in pigs  

Jung, Ji-Youl (Department of Veterinary Medicine, Cheju National University)
Kim, Ki-Seung (Department of Veterinary Medicine, Cheju National University)
Kim, Dae-Yong (College of Veterinary Medicine, Seoul National University)
Kim, Jae-Hoon (Department of Veterinary Medicine, Cheju National University)
Publication Information
Korean Journal of Veterinary Research / v.47, no.3, 2007 , pp. 321-324 More about this Journal
Abstract
Pneumocystis (P.) carinii is an opportunistic fungal pathogen of many animal species and human, which can cause fatal pneumonia in immunocompromised individuals. Three 100-day-old pigs with progressive atrophy, anorexia and respiratory distress were submitted to the Cheju National University for diagnosis. Grossly, the lungs were enlarged with rubbery consistency. Histopathologically, the lungs were characterized by diffuse interstitial pneumonia with thickening of alveolar septa due to infiltration of macrophages and lymphocytes. Alveolar lumens were filled with a foamy eosinophilic proteinaceous material in which numerous punctiform organisms. The organisms were demonstrated as P. carinii by Grocott-methenamine-silver staining and immunohistochemistry in lungs of two pigs. In our best knowledge, this is believed to be the first report of P. carinii pneumonia in pigs in Korea.
Keywords
Grocott's methenamine silver staining; immunohistochemistry; pig; Pneumocystis carinii; pneumonia;
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1 Caswell JL, Williams KJ. The respiratory system. In: Jubb KVF, Kennedy PC, Palmer N (eds.). Pathology of Domestic Animals. 5th ed. p. 593, Elsevier, Toronto, 2007
2 Christopher-Hennings J, Nelson EA, Nelson JK, Hines RJ, Swenson SL, Hill HT, Zimmerman JJ, Katz JB, Yaeger MJ, Chase CCL, Benfield DA. Detection of porcine reproductive and respiratory syndrome virus in boar semen by PCR. J Clin Microbiol 1995, 33, 1730-1734
3 Kim J, Yu JR, Hong ST, Park CS. Detection of Pneumocystis carinii by in situ hybridization in the lungs of immunosuppressed rats. Korean J Parasitol 1996, 34, 177-184   DOI
4 Jensen TK, Boye M, Bille-Hansen V. Application of fluorescent in situ hybridization for specific diagnosis of Pneumocystis carinii pneumonia in foals and pigs. Vet Pathol 2001, 38, 269-274   DOI   ScienceOn
5 Limper AH, Thomas CF, Anders RA, Leof EB. Interactions of parasite and host epithelial cell cycle regulation during Pneumocystis carinii pneumonia. J Lab Clin Med 1997, 130, 132-138   DOI   ScienceOn
6 박소영, 이혜경. 후천성 면역결핍증 환자에서 병발된 주폐포자충 폐렴 및 속립성 폐결핵 중복감염. 대한병리학회지 1994, 28, 657-662
7 Kondo H, Taguchi M, Abe N, Nogami Y, Yoshioka H, Ito M. Pathological changes in epidemic porcine Pneumocystis carinii pneumonia. J Comp Pathol 1993, 108, 261-268   DOI   ScienceOn
8 Sepkowitz KA. Opportunistic infections in patients with and patients without acquired immunodeficiency syndrome. Cli Infect Dis 2002, 34, 1098-1107   DOI   ScienceOn
9 Kondo H, Kuramochi T, Taguclb.i M, Ito M. Serological studies on porcine Pneumocystis carinii pneumonia: kinetics of the antibody titers in swine herds and the association of porcine reproductive and respiratory syndrome virus infection. J Vet Med Sci 1997, 59, 1161-1163   DOI
10 Ellis J, Hassard L, Clark. E, Harding J, Allan G, Willson P, Strokappe J, Martin K, McNeilly F, Meehan B, Todd D, Haines D. Isolation of circovirus from lesions of pigs with postweaning multisystemic wasting syndrome. Can Vet J 1998, 39, 44-51
11 Stringer JR. Pneumocystis carinii: What is it, exactly? Clin Microbiol Rev 1996, 9, 489-498
12 Bauer NL, Paulsrud JR, Bartlett MS, Smith JW, Wilde CE III. Pneumocystis carinii organisms obtained from rats, ferrets, and mice are antigenically different. Infect Immunol 1993, 61, 1315-1319
13 권건영, 전영준, 장은숙. 뉴우모시스티스 카리니 폐렴에서 폐포상피세포와 뉴우모시스티스 카리니의 상호 반응에 관련된 Fibronectin, Vitronectin 및 Surfactant-A, D의 발현. 대한병리학회지 2000, 34, 625-635
14 김숙, 곽정자, 김동원, 진소영, 이동화. 미만성 폐포손상으로 나타난 뉴우모시스티스 카리니 폐렴, 대한병리학회지 1996, 30, 1155-1158
15 Segales J, Domingo M, Chianini F, Majo N, Dominguez J, Darwich L, Mateu E, Immunosuppression in postweaning multisystemic wasting syndrome affected pigs. Vet Microbiol 2004, 98, 151-158   DOI   ScienceOn
16 Larochelle R, Antaya M, Morin M, Magar R. Typing of porcine circovirus in clinical specimens by multiplex PCR. J Virol Methods 1999, 80, 69-75   DOI   ScienceOn