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Antioxidative effects of Houttuynia cordata root on non-lipid oxidative damage  

Hah, Dae-Sik (Gyeongnam Livestock Promotion Institute Middle-branch)
Kim, Chung-Hui (Department of Animal Science and Biotechnology, Jinju National University)
Kim, Euikyung (College of Veterinary Medicine, Gyeongsang National University (Institute of Animal Science))
Kang, Chung-boo (College of Veterinary Medicine, Gyeongsang National University (Institute of Animal Science))
Kim, Jong-shu (College of Veterinary Medicine, Gyeongsang National University (Institute of Animal Science))
Publication Information
Korean Journal of Veterinary Research / v.47, no.1, 2007 , pp. 25-32 More about this Journal
Abstract
Houttuynia cordata root on non-lipid oxidative damage. The antioxidative efects of methanolic (MeOH) extract of Houttuynia cordata rooton non-lipid, including liposome oxidation, oxidation of deoxyribose, protein oxidation, chelating, scavenging,and 2'-deoxyguanosine (2'dG) oxidation were investigated. Houttuynia cordata root exhibited highantioxidative effect in a liposome model system. The inhibitory effect of MeOH extract on deoxyribosedamage exhibited antioxidative effect and it afforded considerable protection against damage to deoxyribose.In addition, MeOH extract at over 300extracts exhibited metal binding ability for hydrogen peroxide. Furthermore, the oxidation of 2'dG to 8-hydroxy-2-deoxyguanosine was inhibited by MeOH extracts, and scavenging activity for hydroxyl radicalexhibited a remarkable effect. The present results on biological model systems showed that MeOH extractswas effective in the protection of non-lipids against various oxidative model systems.
Keywords
antioxidative effect; Houttuynia cordata root; non-lipid; oxidative damage;
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