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Efficacy of Ciprofloxacin for the Control of Streptococcal Infection in Cultured Fish, Flounder(Paralichtyhs olivaceus) and Eel(Anguilla japonica)  

Park, Se Chang (Collage of veterinary medicine, Seoul National University)
Heo, Gang-Joon (Collage of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National university)
Publication Information
Korean Journal of Veterinary Research / v.44, no.4, 2004 , pp. 643-648 More about this Journal
Abstract
Efficacy of ciprofloxacin was evaluated in laboratory and field studies for control of streptococcal infection in flounder and eel. In disc diffussion test, all streptococcal strains showed high sensitivity to the ciprofloxacin. Minimum inhibitory concentrations of ciprofloxacin against all streptococcal strains used in this study were less than $0.195{\mu}g/ml/$. In laboratory studies where fishes were challanged with Streptococcus iniae, significant reductions in mortality were observed among fish receiving ciprofloxacin (in fed) at 100 mg/kg/body weight or more daily for 3 d when compared with mortality of non-medicated controls. Similar results were achieved when 100 mg/kg/body weight of ciprofloxacin was used in field trials.
Keywords
ciprfloxacin; efficacy; streptococcal infection; cultured fish;
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