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Occurrence of Hairless Piglets with Congenital Goiter  

Kim, Jae-hoon (Department of Veterinary Medicine, Cheju National University)
Sohn, Hyun-joo (National Veterinary Research and Quarantine Service)
Kim, Hyoung-ook (Laboratory of Comparative Pathology, Graduate School of Veterinary Medicine, Hokkaido University)
Jean, Young-hwa (National Veterinary Research and Quarantine Service)
Publication Information
Korean Journal of Veterinary Research / v.43, no.3, 2003 , pp. 457-461 More about this Journal
Abstract
A diagnosis of iodine-deficient goiter was confirmed in newborn piglets that were born hairless edematous, and with markedly enlarged thyroid gland. Clinically, most of the piglets were born dead, extreme weakness or dying within a few hours of birth. Gestation periods were prolonged for 3-7 days. Histopathologically, hair follicles were scarce and reduced in size, contained slender hairs, and revealed a shallow penetration into the hypodermis that showed severe diffuse edema. Thyroid glands had severely hyperplastic follicles and poorly staining colloid. The follicles were irregular in size and shape depending on varying amounts of lightly eosinophilic and granular colloid in the lumen. The iodine content of the diet fed to the sows and plasma total thyroxine and triiodothyronine concentration of sows were very low. This is a first report for iodine-deficient goiter in newborn piglets in Korea.
Keywords
piglet; iodine; goiter; skin; thyroid gland;
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  • Reference
1 McDonald, L. E. and Pineda, M. H. VeterinaryEndocrinology and Reproduction, p. 86, 4th ed. Lea &Febiger. Philadelphia, 1989
2 Wrathall, A. E.. Bailey, J., Wells, D. E. and Hebert,C N. Studies on the barker (neonatal respiratcry distress)syndrome in the pig. Comell Vet. 1977, 67, 543-598
3 Beck-Peccoz, P. and Medri, G. Congenital thyroiddisease. Bailliere's Clin. Endocnnol. Metab. 1988, 2,737-759
4 Fowler, E. H. and Calhoun, M. L. The microscopic anatomy of developing fetal pig skin. Am. J. Vet. Res.1964, 25, 156-164
5 The National Reseaix'h Council. Nutrient requirementsof swine. lOth ed. Washington, DC: National Academyof Science, 1998
6 Brenner, K. V., Pethes, G., Gurtler, H., Losonczy, S., and Grun, E. Thyroxine and triiodothyronine blood plasma concentrations in sows and newbom pigs Endokrinologie. 1980, 75, 20-28
7 Kalkus, J. W. A study of goiter and associateds condition in domestic animals, pp. 4-48. Agricultural Experiment Station, Washington, 1920
8 Welchman, D. D., Cranwell, M. P., Wrathall, A. E.,and Christensen, P. An inhehted congenital goiter inpigs. Vet. Rec. 1994, 135, 589-593
9 WrathaM, A. E. Reproductive failure in the pig:diagnosis and control. Vet. Rec. 1977, 100, 230-237
10 Jubb, K. V. F., Kennedy, P. C. and Palmer, N. Pathology of Domestic Animals, pp. 314-320. 4th ed. Academic Press, Inc., San Diego, 1993
11 Itakura, C., Nakano, D. and Goto, M. Histopathologic features of the skin of hairless newbom pigs with goiter. Am. J. Vet. Res. 1979, 40, 111-114
12 Blackwell, T. E., Werdin, R. E., Eisenmenger, M. C., and FitzSimmons, M. A. Goitrogenic effects in offspring of swine fed sulfadiniethoxine and onnetoprim in late gestation. J.A.V.M.A. 1989, 194, 519-523
13 Straw, B. E., Allaire, S. D., Mengeling, W. L., andTaylor, D. J. Disease of Swine, PP. 746-751, 8th ed.lowa State Press, Ames, 1999