Browse > Article

The effect of Phyllostachys nigra var. henenis Strapf leaf extract in the gamma-irradiated mice  

Shin, Dong-Ho (College of Veterinary Medicine, Chonnam National University)
Kim, Jong-Choon (College of Veterinary Medicine, Chonnam National University)
Kim, Se-Ra (College of Veterinary Medicine, Chonnam National University)
Oh, Heon (College of Veterinary Medicine, Chonnam National University)
Park, In-Chul (College of Veterinary Medicine, Chonnam National University)
Oh, Ki-Seok (College of Veterinary Medicine, Chonnam National University)
Chung, Hee-Jong (College of Agriculture and Life Science, Chonnam National University)
Jang, Jong-Sik (Department of Animal Science, Sangju National University)
Kim, Sung-Ho (College of Veterinary Medicine, Chonnam National University)
Publication Information
Korean Journal of Veterinary Research / v.43, no.1, 2003 , pp. 49-55 More about this Journal
Abstract
This study was performed to determine the effect of Phyllostachys nigra var. henenis Strapf leaf extract on jejunal crypt survival, endogenous spleen colony formation and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of gamma-radiation. Phyllostachys nigra var. henenis Strapf administration before irradiation (I.P.: 125 mg/kg of body weight, at 24 hours before irradiation) resulted in an increase of the formation of endogenous spleen colony (p<0.01). The frequency of radiation-induced apoptosis was also reduced by pretreatment of Phyllostachys nigra var. henenis Strapf (I.P.: 280 mg/kg or 28 mg/kg of body weight, at 24 hours before irradiation, p<0.01). These results indicated that Phyllostachys nigra var. henenis Strapf might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the promotion nature of Phyllostachys nigra var. henenis Strapf and its components.
Keywords
Phyllostachys nigra var. henenis Strapf; radiation; apoptosis; spleen colony;
Citations & Related Records
연도 인용수 순위
  • Reference
1 NCP report No. 65. Management of Persons AccidentaIly Contaminated with Radionuclides. 77, 1980
2 MacVittie TJ, Monroy RL, Patchen ML, et al. Therapeutic use of recombinant human G-CSF (rhG-CSF) in a canine model of sublethal and lethal whole body irradiation. Int J RadIat Biol, 57:723-736, 1990
3 Kligerman MM, Shaw MT, Slavid M, et al. Phase I clinical studies with WR2721. Cancer Clin Trials, 3:217-221, 1980
4 Zneg XL, Li XA, Zhang BY. Immunological and hematopoietic effect of Codonopsis pilosula on cancer patients during radiotherapy. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 12:607-608, 1992
5 Wang HB, Zheog QY, Ju DW, et al. Effects of Phytolacca acinosa polysaccharides II on lymphocyte ptoliferation and colony stimulating factor production from mice splenocytes in vitro. Yao Hsueh Hsueh Pao, 28:490-493, 1993
6 Hsu HY, Lian SL, Lin CC. Radioprotective effect of Ganoderma lucidum (Leyss. ex. Fr.) Karst after X-ray irradiation in mice. Am J Chin Med, 18:61-69, 1990
7 Lu G, Yang M, Shen Y, et al. The absorption of Fe, Zn, Cu in siwu, sijunzi, and Liuwei dihuang decoction by small intestine in rats. Chung Kuo Chung Yao Tsa Chih, 16:297-298, 1991
8 정보섭, 김일혁, 김재길, 원색천연약뮬대사전. 남산당, 서울:272, 1984
9 정영호, 식물대백과 : 현화식물편. 아카데미서적, 서울:259, 1991
10 Patt H, Tyree M, Straube RL. Cystein protects against x-irradiation. Science, 110:213-214, 1949
11 Neta R, Douches S, Oppenheim JJ. Interleukin 1 is a radioprotector. J Immunol, 136:2483-2485, 1986
12 Cairnie AB. Adverse effect of radioprotector WR2721. Radiat Res, 94:221-226, 1983
13 IAEA safety series No. 47. Manual on Earty Medical Treatment of Passible Radiation Injury. IAEA, Vienna: 74, 1978
14 Mei QB, Tao TY, Cui B. Advances in the phanna-cological studies of radix Angelica sinensis (Oliv) Diels (Chinese Danggui). Chin Med J Engl, 104:776-781, 1991
15 Washbum LC, Carlton JE, Hayes RL. Distribution of WR-2721 in normal and malignant tissue of mice and rats bearing solid tumors: dependence on tumor type, drug dose and species. Radiat Res, 59:483-575, 1974
16 Yuan Y, Hou S, Lian T, et al. Studies of Rehmannia glutinosa Libosch. f. hueichingensis as a blood tonic. Chung Kuo Chung Yao Tsa Chih, 17:366-368, 1992
17 Shibata M, Yannatake M, Sakamoto M, Kanamori K, Takagi K, Okabe S. Pharmacological studies on bamboo grass. Nippon Yakurigaku Zasshi, 71:481-485, 1975
18 과학백과사전출판사, 약초의 성분과 이용. 일월서각,서울:653-654, 1991
19 Kweon MH, Hwang HJ, Sung HC. Identification and antioxidant activity of novel chlorogenic add derivatives from bamboo (Phyllastachys edulis). J Agric Food Chem, 49:4646-4655, 2001
20 Hu C, Zhang Y, Kitts DD. Evaluation of andoxident and piooxident activities of bamboo Phyllostachys nigra var. henonis leaf extract in vitro. J Agric Food Chem, 48:3170-3176, 2000
21 송주택, 식물학대사전. 거북출판사, 서울: 1126-1127, 1986
22 김남재, 이석주, 권창호 등. 왕대잎(Phyllostachys bam-busoides S. et Z)의 지질과산화억제활성. 생약학회지, 26:368-376, 1995
23 Lee SE, Oh H, Yang JA, et al, Radioprotective effects of two tiaditional Chinese medicine prescriptions: Si-Wu-Tang and Si-Jun-Zi-Tang. Am J Chin Med, 27:387-396. 1999
24 Hsu HY, Ho YH, Lian SL, et al. Preliminary study on the anti-radiation effect of jen-sheng-yang-yung-tang. Am J Chin Med, 21:187-195, 1993
25 Wang Y, Zhu B. The effect of angelica polysaccharide on proliferation and differentiation of hematopoietic progenitor cell. Chung Hua I Hsueh Tsa Chih, 76:363-366, 1996
26 Milas L, Hunter N, Reid BO, et al. Protective effects of S-2-(3-aminoprapylamino) ethylphosphorothioic acid against radiation damage of normal tissues and a fibrosacoma in mice. Cancer Res, 42:1888-1987, 1982
27 Kim SH, Cho CK, Yoo SY, et al. In vivo radio-protective activity of Panax ginseng and diethyldi-thiocarbamate. IN VIVO, 7:467-470, 1993
28 Miyanomae T, Frindel E. Radioprotection of hemopoiesis conferred by Acanthopanax senticosus Harms (Shigoka) administered before or after irradiation. Exp Hemstol, 16:801-806, 1988
29 Hsu HY, Hau DM, Lin CC. Effects of kuei-pi-tang on cellular immunocompetence of gamma-irradiated mice. Am J Chin Med, 21:151-158, 1993
30 Hosokawa Y. Radioprotective effect of Chinese medicinal prescriptions in mice. J Med Pharm Soc for Wakan-Yaku, 3:164-169, 1986
31 Hall EJ. Sadiobiology for the radiologist, 4th ed., J.B. Lippincott Company, Philadelphia, 1994
32 Milas L, Murray D, Brock WA, et at. Radioprotectors in tumor radiotherapy: Factors and settings determining therapeutic ratio. Pharmacol. Ther, 39:179-189, 1988
33 Hsu HY, Ho YH, Lian SL, et al. Preliminary study on antiradiation effect of kuei-pi-tang. Am J Chin Med, 19:275-284, 1991
34 윤기동, 김철영, 허훈. 조릿대잎의 flavone 배당체 성분. 생약학회지, 31:224-227, 2000
35 Sweeney TR. A survey of compounds from the anti-radiation drug development program of the U.S. army medical research & development command. Walter Reed Army Institute of Research. Washington, DC. 1979
36 Li NQ. Clinical and experimental study on shen-qi injection with chemotherapy in the treatment of ma-lignant tumor of digestive tract. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 12:588-592, 1992
37 Ohta S, Sakurai N, Sato Y, et al. Studies on chemical protectors against radiation. XXX. Radioprotective sub-stances of cnidii rhizoma, Yakugaku Zasshi, 110:746-754, 1990
38 Neta R. Role of cytokines in radioprotection. Pharmacol Ther, 39:261-266, 1988