Browse > Article
http://dx.doi.org/10.4070/kcj.2012.42.7.487

Acute Coronary Stent Thrombosis in Cancer Patients: A Case Series Report  

Lee, Joo-Myung (Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital)
Yoon, Chang-Hwan (Division of Cardiology, Department of Internal Medicine, Seoul National University Bundang Hospital)
Publication Information
Korean Circulation Journal / v.42, no.7, 2012 , pp. 487-491 More about this Journal
Abstract
There have been a growing numbers of patients diagnosed with malignancy and coronary artery disease simultaneously or serially. In the era of percutaneous coronary intervention (PCI), stent thrombosis has been a rare but challenging problem. Recently, we experienced two unique cases of acute stent thrombosis in patients with malignancy. The first case showed acute and subacute stent thrombosis after PCI. The second case revealed simultaneous thromboses in stent and non-treated native coronary artery. We believe that we need rigorous precautions in the treatment of patients with coronary artery disease and malignancy, especially with regards to deciding how and whether to revascularize, as well as which anti-platelet agents to select.
Keywords
Coronary thrombosis; Thrombosis; Neoplasms; Pancreatic neoplasms; Lung neoplasms; Coronary angiography; Stent thrombosis;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Iakovou I, Schmidt T, Bonizzoni E, et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA 2005;293:2126-30.   DOI   ScienceOn
2 Blich M, Zeidan-Shwiri T, Petcherski S, Osherov A, Hammerman H. Incidence, predictors and outcome of drug-eluting stent thrombosis in real- world practice. J Invasive Cardiol 2010;22:461-4.
3 Lee AY. Thrombosis in cancer: an update on prevention, treatment, and survival benefits of anticoagulants. Hematology Am Soc Hematol Educ Program 2010;2010:144-9.   DOI
4 Khorana AA, Connolly GC. Assessing risk of venous thromboembolism in the patient with cancer. J Clin Oncol 2009;27:4839-47.   DOI   ScienceOn
5 De Cicco M. The prothrombotic state in cancer: pathogenic mechanisms. Crit Rev Oncol Hematol 2004;50:187-96.   DOI   ScienceOn
6 Nakagawa T, Yasuno M, Tanahashi H, et al. A case of acute myocardial infarction: intracoronary thrombosis in two major coronary arteries due to hormone therapy. Angiology 1994;45:333-8.   DOI   ScienceOn
7 Canale ML, Camerini A, Stroppa S, et al. A case of acute myocardial infarction during 5-fluorouracil infusion. J Cardiovasc Med (Hagerstown) 2006;7:835-7.   DOI   ScienceOn
8 Wijesinghe N, Thompson PI, McAlister H. Acute coronary syndrome induced by capecitabine therapy. Heart Lung Circ 2006;15:337-9.   DOI   ScienceOn
9 Kalapura T, Krishnamurthy M, Reddy CV. Acute myocardial infarction following gemcitabine therapy: a case report. Angiology 1999;50:1021-5.   DOI   ScienceOn
10 Gemici G, Cinçin A, Degertekin M, Oktay A. Paclitaxel-induced ST-segment elevations. Clin Cardiol 2009;32:E94-6.   DOI
11 Lee SP, Suh JW, Park KW, et al. Study design and rationale of 'Influence of Cilostazol-based triple anti-platelet therapy on ischemic complication after drug-eluting stent implantation (CILON-T)' study: a multicenter randomized trial evaluating the efficacy of Cilostazol on ischemic vascular complications after drug-eluting stent implantation for coronary heart disease. Trials 2010;11:87.   DOI
12 Gurbel PA, Bliden KP, Butler K, et al. Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the respond study. Circulation 2010;121:1188-99.   DOI   ScienceOn
13 Montalescot G, Wiviott SD, Braunwald E, et al. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial. Lancet 2009;373:723-31.   DOI   ScienceOn