Browse > Article
http://dx.doi.org/10.5667/tang.2019.0016

Evolvulus alsinoides: A potential antihypertensive herb  

Siraj, Mantasha Binth (Department of Moalajat)
Khan, Asim Ali (CCRUM, Ministry of AYUSH)
Jahangir, Umar (Department of Moalajat)
Hashimi, Ayshah (Department of Moalajat)
Ahmad, Yasmeen (Department of Moalajat)
Publication Information
CELLMED / v.9, no.4, 2019 , pp. 1.1-1.4 More about this Journal
Abstract
In spite of the fact that a variety of unfailing guidelines are existing for the management of hypertension, the problem of inadequate managing of this condition still continues. Several classes of existing antihypertensive drugs are associated with various side-effects. Since ancient times before the advent of anti-hypertensive drugs, this disease has been treated by the prominent classical scholars. Various herbal drugs are being used since ages for the treatment of hypertension and some of them are validated too. Evolvulus alsinoides is also one such herb used in classical literature since ages for various disorders like insanity, anxiety, nervous debility, epilepsy, melancholy, palpitation and many others. This review is to highlight the antihypertensive potential of Evolvulus alsinoides.
Keywords
Anti-hypertensive; herbal drugs; classical literature; Evolvulus alsinoides;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Takahashi H Sympathetic hyperactivity in hypertension (in Japanese).Nihon Rinsho. 2008:66(8):1495-502.
2 Agarwal D Haque M, Sriramula S, Mariappan N, Pariaut R, Francis J.Role of proinflammatory cytokines and redox homeostasis in exercise-induced delayed progression of hypertension in spontaneously hypertensive rats. Hypertension.2009:6(54):1393-1400.
3 Anonymus Causes of Death 2008. Geneva: World Health Organization, 2008.
4 Anonymus Global status report on non-communicable diseases 2010. Geneva: World Health Organization, 2013.
5 Asolkar LV, Kakkar KK, Chakre OJ. Second supplement to glossaryof indian medicinal plants with active principles, Part-I (A-K) (New-Dehli, India: Publications and information directorate), 1992.
6 Austin DF. Evolvulus alsinoides (Convolvulaceae): an American herb in the Old World. Ethnopharmacol. 2008:117(2):185-98.   DOI
7 Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003:289(19):2560-72.   DOI
8 Dodt C, Wellhoner JP, Schutt M, Sayk F. Glucocorticoids and hypertension.Der Internist. 2009:50:36-41.   DOI
9 Edward D. and M.D. Freis, Adverse effects of antihypertensive drugs. [Journal] // GP. - 1954. - Vol. 10. - pp. 32-33.
10 Ganju L, Karan D, Chanda S, Srivastava KK, Sawhney RC, Selvamurthy W. Immunomodulatory effects of agents of plant origin .Biomedicine & Pharmacotherapy.2003.57(7):296-300.   DOI
11 Gomathi D, Kalaiselvi M, Ravikumar G, Sophia D, Gopalakrishnan VK, Uma C. Secondary metabolite credentials of Evolvulus alsinoides by high performance thin layer chromatography. J Biomed Res. 2012:26(4):295-302.   DOI
12 Gomathi D, Ravikumar G, Kalaiselvi M, Devaki K, Uma C. Antioxidant activity and functional group analysis of Evolvulus alsinoides .Chinese Journel of Natural Medicine. 2014:12(11):827-832.   DOI
13 Gupta P, Sharma U, Gupta P, Siripurapu KB, Maurya R. Corrigendum to "Evolvosides C-E, flavonol-4'-O-triglycosides from Evolvulus alsinoides and their anti-stress activity"Bioorganic & Medicinal Chemistry.Bioorg Med Chem. 2013:21(8):2426.   DOI
14 Hwang IS, Ho H, Hoffman BB, Reaven GM. Fructose-induced insulin resistance and hypertension in rats. Hypertension.1987:10(5):512-6.   DOI
15 Joshi U, Dabhi KR, Desai T, Tigar P. Investigation of antihypertensive mechanism of Evolvulus alsinoides in DOCA salt induced hypertensive rats. Journal of Pharmacy Research.2012:5(7):3613-3617.
16 Joshi UH, Ganatra TH, Desai TR, Tirgar PR. Evaluation of antihypertensive activity of evolvulus alsinoides in adrenaline. International journal of pharmacy and pharmaceutical sciences. 2012:4(4):194-198.
17 Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005:365(9455):217-23.   DOI
18 Khan QA, Khan AA, Jabeen A, Jahangir U, Parveen S. Efficacy of sankhaholi (evolvulus alsinoides linn.) In the management of essential hypertension: a randomized standard control clinical study. International Journal of Pharmaceutical Sciences and Research. 2018:10(7):3467-3473.
19 Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K et. al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012:380(9859):2224-60.   DOI
20 Moghadam NS, AK HV, Talkad MS, Nagaraj M, Manasa DR. Anti-Bacterial and Anti-Oxidant Activities of Evolvulus Alsinoides Linn. J Pharm Biol Sci. 2017:12(01):83-86.
21 Najmul G. Khazaeynul Advia and Tarjumn-u-Tib. (Lahaur, Pakistan: Main Bazar Qasur Pura), YNM .Vol. 2:pp. 963-64.
22 Pierdomenico SD, Di Nicola M, Esposito AL, Di Mascio R, Ballone E, Lapenna D, Cuccurullo F. Prognostic value of different indices of blood pressure variability in hypertensive patients. Am J Hypertens. 2009:22(8):842-7.   DOI
23 Pimenta E, Oparil S. Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors. Vasc Hlth Risk Manag.2009:5:453-63.
24 Sagnella GA, Swift PA.The renal epithelial sodium channel: Genetic heterogeneity and implications for the treatment of high blood pressure. Curr Pharma Design. 2006:12:2221-34.   DOI
25 Sesso HD, Buring JE, Rifai N, Blake GJ, Gaziano JM, Ridker PM. C-reactive protein and the risk of developing hypertension. JAMA. 2003:290(22):2945-51.   DOI
26 Singh A. Review of Ethnomedicinal Uses and Pharmacology of Evolvulus alsinoides Linn. Ethnobotanical Leaflets. 2008:12:734-40.
27 Tabassum N, Ahmad F. Role of natural herbs in the treatment of hypertension. Pharmacognosy Review.2011:5(9):30-40.   DOI
28 Kiritikar KR, Basu BD. Indian Medicinal Plants. 2nd edition. (Newdelhi: Bishen Singh Mahendra Pal Singh), 1984.
29 Wright JM, Musini VM, Gill R. First-line drugs for hypertension. Cochrane Database Syst Rev. 2018:18(4):CD001841.
30 Yadav MK, Singh SK, TRIPATHI JS, Tripathi YB. Phytochemical screening and in-vitro antioxidant activity of evolvulus alsinoides extracts. International Journal of Pharmaceutical Sciences and Research. 2018:9(3):1247-50.
31 Zillich AJ, Garg J, Basu S, Bakris GL, Carter BL. Thiazide diretics, potassium and the development of diabetes: A quantitative review. Hypertension.2006:48(2):219-24.   DOI
32 Anonymus. Herbulecure India, "SANKHAPUSPI (Evolvulus alsinoides). World's Premier Health information site.
33 Anonymus. Noncommunicable diseases country Profiles 2011. Geneva, Switzerland: 2103. (Assessed on 13 June 2019)