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http://dx.doi.org/10.3947/ic.2018.50.4.340

Virulence Genes, Antibiotic Resistance and Capsule Locus Polymorphisms in Enterococcus faecalis isolated from Canals of Root-Filled Teeth with Periapical Lesions  

Saffari, Fereshteh (Department of Microbiology and Virology, School of Medicine, Kerman University of Medical Sciences)
Sobhanipoor, Mohammad Hossein (Faculty of Medicine, Microbiology Section, Bam University of Medical Sciences)
Shahravan, Arash (Endodontology Research Center, Kerman University of Medical Sciences)
Ahmadrajabi, Roya (Faculty of Medicine, Microbiology Section, Bam University of Medical Sciences)
Publication Information
Infection and chemotherapy / v.50, no.4, 2018 , pp. 340-345 More about this Journal
Abstract
Frequent isolation of Enterococcus faecalis from root canal treated teeth with apical periodontitis, has proposed the role of this organism in endodontic treatment failures. Different factors have been suggested in the pathogenicity of this organism. In this study, 22 E. faecalis isolates from canals of root-filled teeth were identified, and phenotypic and genotypic characteristics were investigated. No resistance to vancomycin and gentamicin was noted, and most isolates (91%) were susceptible to ampicillin. Biofilm formation was detected in 73% of the isolates and may be considered as the most important virulence factor involved in the pathogenesis of these isolates.
Keywords
Enterococcus faecalis; Apical periodontitis; Virulence factors; Antibiotic resistance; Biofilm;
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