Neuroprotective Effect of Dizocilpine (MK-801) via Anti-apoptosis on Hypoxic-ischemic Brain Injury in Neonatal Rats |
Seo, Min-Ae
(Department of Pediatrics, School of Medicine, Catholic University of Daegu)
Lee, Hyun-Ju (Department of Pediatrics, School of Medicine, Catholic University of Daegu) Choi, Eun-Jin (Department of Pediatrics, School of Medicine, Catholic University of Daegu) Kim, Jin-Kyung (Department of Pediatrics, School of Medicine, Catholic University of Daegu) Chung, Hai-Lee (Department of Pediatrics, School of Medicine, Catholic University of Daegu) Kim, Woo-Taek (Department of Pediatrics, School of Medicine, Catholic University of Daegu) |
1 | Weitzdoerfer R, Pollak A, Lubec B. Perinatal asphyxia in the rat has lifelong effects on morphology, cognitive functions, and behavior. Semin Perinatol 2004;28:249-56. DOI ScienceOn |
2 | Chan PH. Mitochondrial dysfunction and oxidative stress as determinants of cell death/survival in stroke. Ann N Y Acad Sci 2005;1042:203-9. DOI ScienceOn |
3 | Zipfel GJ, Babcock DJ, Lee JM, Choi DW. Neuronal apoptosis after CNS injury: the roles of glutamate and calcium. J Neurotrauma 2000;17:857-69. DOI ScienceOn |
4 | Clawson TF, Vannucci SJ, Wang GM, Seaman LB, Yang XL, Lee WH. Hypoxia-ischemia-induced apoptotic cell death correlates with IGF-I mRNA decrease in neonatal rat brain. Biol Signals Recept 1999;8:281-93. DOI |
5 | Bågenholm R, Nilsson UA, Götborg CW, Kjellmer I. Free radicals are formed in the brain of fetal sheep during reperfusion after cerebral ischemia. Pediatr Res 1998;43:271-5. |
6 | Giulian D, Vaca K. Inflammatory glia mediate delayed neuronal damage after ischemia in the central nervous system. Stroke 1993;24(12 Suppl):I84-90. |
7 | Graham EM, Sheldon RA, Flock DL, Ferriero DM, Martin LJ, O'Riordan DP, et al. Neonatal mice lacking functional Fas death receptors are resistant to hypoxic-ischemic brain injury. Neurobiol Dis 2004;17:89-98. DOI ScienceOn |
8 | Allan SM, Rothwell NJ. Inflammation in central nervous system injury. Philos Trans R Soc Lond B Biol Sci 2003;358:1669-77. DOI ScienceOn |
9 | Huang SS, Tsai MC, Chih CL, Hung LM, Tsai SK. Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia. Life Sci 2001;69:1057-65. DOI ScienceOn |
10 | Ashwal S, Pearce WJ. Animal models of neonatal stroke. Curr Opin Pediatr 2001;13:506-16. DOI ScienceOn |
11 | Vannucci RC. Hypoxic-ischemic encephalopathy. Am J Perinatol 2000;17:113-20. DOI ScienceOn |
12 | Towfighi J, Mauger D, Vannucci RC, Vannucci SJ. Influence of age on the cerebral lesions in an immature rat model of cerebral hypoxiaischemia: a light microscopic study. Brain Res Dev Brain Res 1997; 100:149-60. DOI ScienceOn |
13 | Wyllie AH. Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview. Cancer Metastasis Rev 1992; 11:95-103. DOI ScienceOn |
14 | Gerschenson LE, Rotello RJ. Apoptosis: a different type of cell death. FASEB J 1992;6:2450-5. DOI |
15 | Johnson EM Jr, Deckwerth TL. Molecular mechanisms of developmental neuronal death. Annu Rev Neurosci 1993;16:31-46. DOI ScienceOn |
16 | Dong JW, Zhu HF, Zhu WZ, Ding HL, Ma TM, Zhou ZN. Intermittent hypoxia attenuates ischemia/reperfusion induced apoptosis in cardiac myocytes via regulating Bcl-2/Bax expression. Cell Res 2003;13:385-91. DOI ScienceOn |
17 | Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG, Youle RJ. Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol 1997;139:1281-92. DOI ScienceOn |
18 | Thornberry NA, Lazebnik Y. Caspases: enemies within. Science 1998;281:1312-6. DOI |
19 | Porter AG, Janicke RU. Emerging roles of caspase-3 in apoptosis. Cell Death Differ 1999;6:99-104. DOI ScienceOn |
20 | Qin ZH, Wang Y, Chase TN. Stimulation of N-methyl-D-aspartate receptors induces apoptosis in rat brain. Brain Res 1996;725:166-76. |
21 | Amir G, Ramamoorthy C, Riemer RK, Reddy VM, Hanley FL. Neonatal brain protection and deep hypothermic circulatory arrest: pathophysiology of ischemic neuronal injury and protective strategies. Ann Thorac Surg 2005;80:1955-64. DOI ScienceOn |
22 | Choi DW. Cerebral hypoxia: some new approaches and unanswered questions. J Neurosci 1990;10:2493-501. |
23 | Garthwaite J, Boulton CL. Nitric oxide signaling in the central nervous system. Annu Rev Physiol 1995;57:683-706. DOI ScienceOn |
24 | Marini AM, Rabin SJ, Lipsky RH, Mocchetti I. Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate. J Biol Chem 1998;273: 29394-9. DOI |
25 | Mukhin AG, Ivanova SA, Knoblach SM, Faden AI. New in vitro model of traumatic neuronal injury: evaluation of secondary injury and glutamate receptor-mediated neurotoxicity. J Neurotrauma 1997;14:651-63. DOI ScienceOn |
26 | Ayala GX, Tapia R. Late N-methyl-D-aspartate receptor blockade rescues hippocampal neurons from excitotoxic stress and death after 4-aminopyridine-induced epilepsy. Eur J Neurosci 2005;22:3067- 76. DOI ScienceOn |
27 | Kocaeli H, Korfali E, Oztürk H, Kahveci N, Yilmazlar S. MK-801 improves neurological and histological outcomes after spinal cord ischemia induced by transient aortic cross-clipping in rats. Surg Neurol 2005;64 Suppl 2:S22-6; discussion S27. |
28 | Ford LM, Sanberg PR, Norman AB, Fogelson MH. MK-801 prevents hippocampal neurodegeneration in neonatal hypoxicischemic rats. Arch Neurol 1989;46:1090-6. DOI ScienceOn |
29 | Han RZ, Hu JJ, Weng YC, Li DF, Huang Y. NMDA receptor antagonist MK-801 reduces neuronal damage and preserves learning and memory in a rat model of traumatic brain injury. Neurosci Bull 2009;25:367-75. DOI ScienceOn |
30 | Jantas D, Lason W. Different mechanisms of NMDA-mediated protection against neuronal apoptosis: a stimuli-dependent effect. Neurochem Res 2009;34:2040-54. DOI ScienceOn |
31 | Lam TT, Siew E, Chu R, Tso MO. Ameliorative effect of MK-801 on retinal ischemia. J Ocul Pharmacol Ther 1997;13:129-37. DOI ScienceOn |
32 | Vannucci RC, Vannucci SJ. A model of perinatal hypoxic-ischemic brain damage. Ann N Y Acad Sci 1997;835:234-49. DOI |
33 | Lam TT, Abler AS, Kwong JM, Tso MO. N-methyl-D-aspartate (NMDA)--induced apoptosis in rat retina. Invest Ophthalmol Vis Sci 1999;40:2391-7. |
34 | Zhang X, Boulton AA, Zuo DM, Yu PH. MK-801 induces apoptotic neuronal death in the rat retrosplenial cortex: prevention by cycloheximide and R(-)-2-hexyl-N-methylpropargylamine. J Neurosci Res 1996;46:82-9. DOI ScienceOn |
35 | Brewer GJ. Isolation and culture of adult rat hippocampal neurons. J Neurosci Methods 1997;71:143-55. DOI ScienceOn |
36 | Feng Y, Fratkins JD, LeBlanc MH. Treatment with tamoxifen reduces hypoxic-ischemic brain injury in neonatal rats. Eur J Pharmacol 2004;484:65-74. DOI ScienceOn |
37 | Greenwood K, Cox P, Mehmet H, Penrice J, Amess PN, Cady EB, et al. Magnesium sulfate treatment after transient hypoxia-ischemia in the newborn piglet does not protect against cerebral damage. Pediatr Res 2000;48:346-50. DOI ScienceOn |
38 | Vannucci RC, Connor JR, Mauger DT, Palmer C, Smith MB, Towfighi J, et al. Rat model of perinatal hypoxic-ischemic brain damage. J Neurosci Res 1999;55:158-63. DOI ScienceOn |
39 | MacDonald HM, Mulligan JC, Allen AC, Taylor PM. Neonatal asphyxia. I. Relationship of obstetric and neonatal complications to neonatal mortality in 38,405 consecutive deliveries. J Pediatr 1980;96:898-902. DOI |
40 | Delivoria-Papadopoulos M, Mishra OP. Mechanisms of cerebral injury in perinatal asphyxia and strategies for prevention. J Pediatr 1998;132:S30-4. DOI ScienceOn |