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http://dx.doi.org/10.4191/kcers.2018.55.2.12

Preparation and Properties of Hydroxyapatite/Methylcellulose for Bone Graft  

Tak, Woo-Seong (Department of Nano Fusion Technology, Pusan National University)
Kim, Dong-Jun (Department of Nano Fusion Technology, Pusan National University)
Ryu, Su-Chak (Department of Nanomechatronics, Pusan National University)
Publication Information
Journal of the Korean Ceramic Society / v.55, no.2, 2018 , pp. 145-152 More about this Journal
Abstract
Although many bone graft materials have been developed, powder graft materials are somewhat difficult to use in surgery. To solve this problem, a bone graft material in the form of a viscous paste was prepared. Hydroxyapatite was used as a bone graft material, and methyl cellulose was used to impart viscosity. Three cases of samples were prepared, and freeze-dried block type and sintered specimens were made from the paste. The recrystallization of the graft material in a simulated body fluid and the degree of graft adhesion with a tooth were observed by scanning electron microscopy (SEM). The test for cytotoxicity was carried out and the sample was grafted into the back of a mouse to confirm the presence or absence of side effects in the animal's body. Based on these investigations, composites of this type are expected to be applicable for bone grafts.
Keywords
Hydroxyapatite; Methylcellulose; Freeze-drying; Paste; Rats;
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