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http://dx.doi.org/10.4191/KCERS.2011.48.1.026

DCPD Formation and Conversion to HAp in Glass and Glass-ceramic Bone Cement  

Lim, Hyung-Bong (Department of Materials Science and Engineering, Inha University)
Kim, Cheol-Young (Department of Materials Science and Engineering, Inha University)
Publication Information
Journal of the Korean Ceramic Society / v.48, no.1, 2011 , pp. 26-33 More about this Journal
Abstract
The glass in the system of CaO-$SiO_2-P_2O_5$ and the corresponding glass-ceramics are prepared for bone cements and the behaviors of the hardening and hydroxyapatite formation were studied for the glass and glass-ceramic powders. The glass crystallized into apatite, $\alpha$-wollastonite and $\beta$-wollastonite depending on the glass composition when they were heat-treated at $950^{\circ}C$ for 4 h. A DCPD (dicalcium phosphate dihydrate : $CaHPO_4{\cdot}2H_2O$) was developed when the prepared glass and glass-ceramic powders were mixed with 3M-$H_3PO_4$ solution. The DCPD (Ca/P=1.0) transformed to HAp (Ca/P=1.67) when the bone cement was soaked in simulated body fluid (SBF), and this HAp formation strongly depended on the releasing capacity of $Ca^{2+}$ ions from the glass and glass-ceramic cements. The glass-ceramic bone cement containing $\alpha$-wollastonite crystals showed faster transformation of DCPD to HAp than other glass-ceramics containing $\alpha$- and $\beta$-wollastonite crystals. No hydroxyapatite was observed when the glass-ceramic bone cement containing apatite crystals (36P6C) was soaked in SBF even for 1 month, because no $Ca^{2+}$ ion can be released from the stable apatite crystals.
Keywords
Bone cement; Glass; Glass-ceramics; Hydroxyapatite; Dicalcium phosphate dihydrate;
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