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http://dx.doi.org/10.4191/KCERS.2008.45.1.625

Effect of Storage Conditions on the Setting Properties of Brushite Bone Cement Containing Granular β-Tricalcium Phosphate  

Lee, Sun-Ae (School of Advanced Materials Engineering, The Center for Green Materials Technology, Andong National University)
Chung, Tai-Joo (School of Advanced Materials Engineering, The Center for Green Materials Technology, Andong National University)
Oh, Kyung-Sik (School of Advanced Materials Engineering, The Center for Green Materials Technology, Andong National University)
Publication Information
Journal of the Korean Ceramic Society / v.45, no.10, 2008 , pp. 625-630 More about this Journal
Abstract
In the bone cement composed of dense granules of $\beta-Ca_3(PO_4){_2}(\beta-TCP)$ and $Ca(H_2PO_4){_2}H_2O$, the compressive strength, setting time and temperature rise were measured to observe the degradation of cement with respect to the stored days before setting. Decreases of compressive strength and temperature rise were observed, while setting time increased with respect to the stored days. The similar trends were repeated with the increase of temperature of storage. Such a change virtually meant the fading of the character of cement and it took place only when the two starting materials were mixed during storage. The degradation could be mitigated taking advantage of granular $\beta$-TCP instead of powdery one. The formation of $CaHPO_4$, which resulted from reaction with ambient humidity, was attributed to the degradation observed during storage. Dependence of the degradation behavior on mixing and temperature during storage was discussed in terms of the driving force for reaction of cement.
Keywords
Bone cement; Granular $\beta$-TCP; Storage; DCPD; DCP;
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1 F. Theiss, D. Apelt, B. Brand, A. Kutter, K. Zlinksky, M. Bohner, S. Matter, C. Frei, J. A. Auer, and B. von Rechenber, "Biocompatibility and Resorption of a Brushite Calcium Phosphate Cement," Biomaterials, 26 [21] 4383-94 (2008)
2 E. Charriere, S. Terrazzoni, C. Pittet, Ph. Mordasini, M. Dutoit, J. Lemaitre, and Ph. Zysset, "Mechanical Characterization of Brushite and Hydroxyapatite Cements," Biomaterials, 22 [21] 2937-45 (2001)   DOI   ScienceOn
3 A. A. Mirtchi, J. Lemaitre, and N. Terao, "Calcium Phosphate Cements: Study of the $\beta$-tricalicum Phosphate-Monocalcium Phosphate System," Biomaterials, 10 [7] 475-80 (1989)   DOI   ScienceOn
4 C. Pittet and J. Lemaitre, "Mechanical Characterization of Brushite Cements: A Mohr Circles' Approach," J. Biomed. Mater. Res: Appl. Biomat., 53 [6] 769-80 (2000)   DOI   ScienceOn
5 M Bohner, "Calcium Orthophosphates in Medicine: from Ceramics to Calcium Phosphate Cements," Injury, 31:S-D 37-47 (2000)   DOI   ScienceOn
6 Private Communications with Kyungwon Medical Co
7 S. A. Lee, T. J. Chung, K. A. Lee, H. M. Kim, and K. S. Oh, "Effect of Storage Conditions Prior to Mixing of $\beta$-TCP Based Bone Cement on the Reaction Products and the Setting," Key Engineering Materials, 361-363 351-354 (2008)   DOI
8 F. C. M. Drissens, M. G. Boltong, O. Bermudez, J. A. Planell, M. P. Ginebra, and E. Fernandez, "Effective Formulations for the Preparation of Calcium Phosphate Bone Cements," J. Mater. Sci. Mater. Med., 5 [3] 164-70 (1994)   DOI
9 X. Lu, Y. B. Wang, J. X. Wang, S. X. Qu, J. Weng, R. L. Xin, and Y. Leng, "Calcium Phosphate Crystal Growth under Controlled Environment through Urea Hydrolysis," J. Cryst. Growth, 297 396-402 (2006)   DOI   ScienceOn
10 S. V. Dorozhkin, "Calcium Orthophosphates," J. Mater. Sci., 42 [4] 1061-95 (2007)   DOI
11 J. C. Elliott, "Structure and Chemistry of the Apatites and Other Calcium Orthophosphates," pp. 6-11, Elsevier, Amsterdam, London, New York, Tokyo, 1994
12 K. S. Oh, H. W. Choi, and S. R. Kim, "Temperature Rise and Setting of $\beta$-TCP-MCPM Bone Cement Containing Dense $\beta$-TCP Granules," Current Applied Physics, 5 489-92 (2005)   DOI   ScienceOn
13 M. Bohner and U. Gbureck, "Thermal Reactions of Brushite Cements," J. Biomed. Mat. Res. Part.B, 84B [2] 375-85 (2008)   DOI   ScienceOn
14 K. S. Oh, S. R. Kim, and P. Boch, "Synthesis and Properties of Bone Cement Containing Dense $\beta$-TCP Granules," Key Engineering Materials, 254-256 237-240 (2004)   DOI