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http://dx.doi.org/10.4191/KCERS.2008.45.1.584

Fabrication and Properties of Bioactive Porous Ceramics for Bone Substitution  

Lee, Lak-Hyoung (School of Advanced Materials Engineering, Andong National University)
Ha, Jung-Soo (School of Advanced Materials Engineering, Andong National University)
Publication Information
Journal of the Korean Ceramic Society / v.45, no.10, 2008 , pp. 584-588 More about this Journal
Abstract
Porous hydroxyapatite(HA) and HA-coated porous $Al_2O_3$ possessing pore characteristics required for bone substitutes were prepared by a slurry foaming method combined with gelcasting. The HA coating was deposited by heating porous $Al_2O_3$ substrates in an aqueous solution containing $Ca^{2+}$ and ${PO_4}^{3-}$ ions at $65{\sim}95^{\circ}C$ under ambient pressure. The pore characteristic, microstructure, and compressive strength were investigated and compared for the two kinds of samples. The porosity of the samples was about 81% and 80% for HA and $Al_2O_3$, respectively with a highly interconnected network of spherical pores with size ranging from 50 to $250{\mu}m$. The porous $Al_2O_3$ sample showed much higher compressive strength(25 MPa) than the porous HA sample(10 MPa). Fairly dense and uniform HA coating(about $2{\mu}m$ thick) was deposited on the porous $Al_2O_3$ sample. Since the compressive strength of cancellous bone is $2{\sim}12$ MPa, both the porous HA and HA-coated porous $Al_2O_3$ samples could be successfully utilized as scaffolds for bone repair. Especially the latter is expected suitable for load bearing bone substitutes due to its excellent strength.
Keywords
Porous hydroxyapatite; Porous alumina; Hydroxyapatite coating; Bone substitutes;
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Times Cited By KSCI : 3  (Citation Analysis)
Times Cited By SCOPUS : 2
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