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http://dx.doi.org/10.4191/KCERS.2008.45.1.579

Fabrication and Characterization of Porous TCP coated Al2O3 Scaffold by Polymeric Sponge Method  

Sarkar, Swapan Kumar (Department of Biomedical Engineering and Materials, School of Medicine, Soonchunhyang University)
Kim, Young-Hee (Department of Biomedical Engineering and Materials, School of Medicine, Soonchunhyang University)
Kim, Min-Sung (Department of Biomedical Engineering and Materials, School of Medicine, Soonchunhyang University)
Min, Young-Ki (Department of Biomedical Engineering and Materials, School of Medicine, Soonchunhyang University)
Yang, Hun-Mo (Department of Biomedical Engineering and Materials, School of Medicine, Soonchunhyang University)
Song, Ho-Yeon (Department of Biomedical Engineering and Materials, School of Medicine, Soonchunhyang University)
Lee, Byong-Taek (Department of Biomedical Engineering and Materials, School of Medicine, Soonchunhyang University)
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Abstract
A porous $Al_2O_3$, scaffold coated with tricalcium phosphate(TCP) was fabricated by replica method using polyurethane(PU) foam as a fugitive material. Successive coatings of $Al_2O_3$ and hydroxyapatite(HAp) were applied via dip coating onto polyurethane foam, which has a slender and well interconnected network. A porous structure was obtained after sequentially burning out the foam and then sintering at $1500^{\circ}C$. The HAp phase was changed to TCP phase at high temperature. The scaffold showed excellent interconnected porosity with pore sizes ranging from $300{\sim}700{\mu}m$ in diameter. The inherent well interconnected structural feature of PU foam remained intact in the fabricated porous scaffold, where the PU foam material was entirely replaced by $Al_2O_3$ and TCP through a consecutive layering process. Thickness of the $Al_2O_3$ base and the TCP coating was about $7{\sim}10{\mu}m$ each. The TCP coating was homogeneously dispersed on the surface of the $Al_2O_3$ scaffold.
Keywords
TCP coating; Scaffold; Porous structure;
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