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http://dx.doi.org/10.4191/KCERS.2006.43.8.504

Fabrication of Functionally Gradient Porous Al2O3-(t-ZrO2)/HAp Composites and their In-Vitro Study  

Kim, Ki-Ho (School of Advanced Materials Engineering, Engineering College, Kongju National University)
Kim, Young-Hee (Department of Microbiology, School of Medicine, Soonchunhyang University)
Song, Ho-Yeon (Department of Microbiology, School of Medicine, Soonchunhyang University)
Lee, Byong-Taek (School of Advanced Materials Engineering, Engineering College, Kongju National University)
Publication Information
Journal of the Korean Ceramic Society / v.43, no.8, 2006 , pp. 504-508 More about this Journal
Abstract
Functionally gradient porous $Al_2O_3-(t-ZrO_2)/HAp$ composites consist of 3 layers were fabricated using the multi-pass extrusion process at the various temperatures. The continuous pores were homogeneously formed in the $2^{nd}$ passed samples and their size was about $180{\mu}m$ in diameter. In the porous composites sintered at $1200-1400^{\circ}C$, the relative density and bending strength increased with the sintering temperature. The maximum values of relative density and bending strength in the $2^{nd}$ passed $Al_2O_3-(t-ZrO_2)/HAp$ composites were 62.2% and 107.8 MPa, respectively. In order to investigate the growth behavior of osteogenic cells on the functionally gradient porous $Al_2O_3-(t-ZrO_2)/HAp$ composites, an in vitro test was performed, using human osteoblast-like MG-63 cells. The cells were well attached and grown on the rough surface of the inside of the functionally gradient porous body.
Keywords
$Al_2O_3-(t-ZrO_2)/HAp$ composites; Functionally gradient; Multi-pass extrusion; In-vitro;
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