Matrix metalloproteinase-1 suppression and type-1 procollagen synthesis promoting effects of Uncaria gambir
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Lee, Jaemin
(Department of Oral Pathology, School of Dentistry, Kyungpook National University)
Kim, Dong-Hee (National Development Institute of Korean Medicine) Kim, Eun-Woo (Department of Life Science and Biotechnology, Dong-Eui University) Kwon, Hyun Ju (Department of Life Science and Biotechnology, Dong-Eui University) Kim, Byung Woo (Department of Life Science and Biotechnology, Dong-Eui University) Cho, Jae-Hyon (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) Kim, Hyun-Joo (Crop Post-harvest Technology Division, National Institute of Crop Science, Rural Development Administration) Kim, Tae Hoon (Blue-Bio Industry Regional Innovation Center, Dong-Eui University) |
1 | Park EK, Ahn SR, Kim DH, Lee EW, Kwon HJ, Kim BW, Kim TH (2014) Effects of unripe apple polyphenols on the expression of matrix metalloproteinase-1 and type-1 procollagen in ultraviolet irradiated human skin fibroblasts. J Korean Soc Appl Biol Chem, 57, 449-455 DOI |
2 | Singleton VL, Orthofer R, Lamuela-Raventos RM (1999) Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods Enzymol, 299, 152-178 |
3 | Nagase H, Woessner JF (1999) Matrix metalloproteinases. J Biol Chem, 274, 21491-21494 DOI |
4 | Abe N, Ito T, Ohguchi K, Nasu M, Mastuda Y, Oyama M, Nozawa Y, Ito M, Iinuma M (2010) Resveratrol oligomers from Vatica albiramis. J Nat Prod, 73, 1499-1506 DOI |
5 | Kim MR, Moon HI, Chung JH, Moon YH, Hahm KS, Woo ER (2004) Matrix metalloproteinase-1 inhibitor from the stem bark of Styrax japonica S. et Z.. Chem Pharm Bull, 52, 1466-1469 DOI |
6 | Min W, Liu X, Quin Q, Lin B, Wu D, Wang M, Ahmad I, Yusuf N, Luo D (2014) The effects of baicalin against UVA-induced photoaging in skin fibroblasts. Am J Chin Med, 42, 709-727 DOI |
7 | Fisher GJ, Datta SC, Talwar HS, Wang ZQ, Varani J, Kang S, Voorhees JJ (1996) Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature, 379, 335-339 DOI |
8 | Kavitha O, Thampan RV (2008) Factors influencing collagen biosynthesis. J Cell Biochem, 104, 1150-1160 DOI |
9 | Scharffetter K, Wlaschek M, Hogg A, Bolsen K, Schothorst A, Goerz G, Krieg T, Plewig G (1991) UVA irradiation induces collagenase in human dermal fibroblasts in vitro and in vivo. Arch Dermatol Res, 283, 506-511 DOI |
10 | Chung JH, Seo JY, Choi HR, Lee MK, Youn CS, Rhie GE, Cho KH, Kim KH, Park KC, Eun HC (2001) Modulation of skin collagen metabolism in aged and photoaged human skin in vivo. J Invest Dermatol, 117, 1218-1224 DOI |
11 | Kim JE, Shin MH, Chung JH (2013) Epigallocatechin-3-gallate prevents heat shock-induced MMP-1 expression by inhibiting AP-1 activity in human dermal fibroblasts. Arch Dermatol Res, 305, 595-602 DOI |
12 | Lim TG, Jung SK, Kim JE, Kim Y, Lee HJ, Jang TS, Lee KW (2013) NADPH oxidase is a novel target of delphinidin for the inhibition of UVB-induced MMP-1 expression in human dermal fibroblasts. Exp Dermatol, 22, 428-430 DOI |
13 | Talwar HS, Griffiths CEM, Fisher GJ, Hamilton TA, Voorhees JJ (1995) Reduced type I and type III procollagens in photodamaged adult human skin. J Invest Dermatol, 105, 285-290 DOI |
14 | Visse R, Nagase H (2003) Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res, 92, 827-839 DOI |
15 | Sternlicht MD, Werb Z (2001) How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol, 17, 463-516 DOI |
16 | Varani J, Warner RL, Gharaee-Kermani M, Phan SH, Kang S, Chung JH, Wang ZQ, Datta SC, Fisher GJ, Voorhees JJ (2000) Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol, 114, 480-486 DOI |
17 | Risdale CE (1978) A revision of Mitragyna and Uncaria (Rubiaceae). Blumea, 24, 43-100 |
18 | Perry LM, Metzger J (1980) Medicinal Plants of East and Southeast Asia: arributed properties and uses. MIT press, Cambridge, MA, USA, p 395 |
19 | Taniguchi S, Kuroda K, Doi K, Tanabe M, Shibata T, Yoshida T, Hatano T (2007) Revised structures of gambiriins A1, A2, B1, and B2, chalcane-flavan dimers from gambir (Uncaria gambir extract). Chem Pharm Bull, 55, 268-272 DOI |
20 | Chen KC (1968) Gambirdine and isogambirdine, the alkaloids from Uncaria gambir (Hunt) Roxb. Tetrahedron Lett, 30, 3403-3406 |
21 | Moon HI, Lee J, Chung JH (2006) The effect of erythrodiol-3-acetate on the expressions of matrix metalloproteinase-1 and type-1 procollagen caused by ultraviolet irradiated cultured primary old aged human skin fibroblasts. Phytomedicine, 13, 707-711 DOI |
22 | Oh HI, Shim JS, Gwon SH, Kwon HJ, Hwang JK (2009) The effect of xanthorrhizol on the expression of matrix metalloproteinase-1 and type-I procollagen in ultravioletirradiated human skin fibrobalsts. Phytother Res, 23, 1299-1302 DOI |
23 | Hong YF, Lee HY, Jung BJ, Jang S, Chung DK, Kim H (2015) Lipoteichoic acid isolated from Lactobacillus plantarum down-regulates UV-induced MMP-1 expression and up-regulates type I procollagen through the inhibition of reactive oxygen species generation. Mol Immunol, 67, 248-255 DOI |
24 | Taniguchi S, Kuroda K, Doi K, Inada K, Yoshikado N, Yoneda Y, Tanabe M, Shibata T, Yoshida T, Hatano T (2007) Evaluation of gambir quality based on quantitative analysis of polyphenolic constituents. Yakugaku Zasshi, 127, 1291-1300 DOI |
25 |
Kim TW, Choi HJ, Eom SH, Lee JM, Kim TH (2014) Potential |
26 | Yimam M, Lee YC, Kim TW, Moore B, Jiao P, Hong M, Kim HJ, Nam JB, Kim MR, Oh JS, Cleveland S, Hyun EJ, Chu M, Jia Q (2015) Analgesic and anti-inflammatory effect of UP3005, a botanical composition containing two standardized extracts of Uncaria gambir and Morus alba. Pharmacognosy Res, 7, S39-46 DOI |
27 | Sazwi NN, Nalina T, Abdul Rahim ZH (2013) Antioxidant and cytoprotective activities of Piper betle, Areca catechu, Uncaria gambir and betel quid with and without calcium hydroxide. BMC complementary Altern Med, 13, 351-362 DOI |
28 | Carmichael J, DeGraff WG, Gazdar AF, Minna JD Mitchell JB (1987) Evaluation of a tetrazolium based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res, 47, 936-942 |
29 | Gross J, Lapiere CM (1962) Collagenolytic activity in amphibian tissues: a tissue culture assay. Proc Natl Acad Sci USA, 48, 1014-1022 DOI |
30 | Kim YH, Chung CB, Kim JG, Ko KI, Park SH, Kim JH, Eom SY, Kim YS, Hwang YI, Kim KH (2008) Anti-wrinkle activity of ziyuglycoside I isolated from a Sanguisorba officinalis root extract and its application as a cosmeceutical ingredient. Biosci Biotechnol Biochem, 72, 303-311 DOI |
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