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Anti-inflammatory and Cellular Protective Effects on Hydrogen Peroxide-induced Cytotoxicity of Grasshopper Extracts  

Park, Ja-Young (Department of Food Science & Technology, Kyungpook National University)
Heo, Jin-Chul (Department of Food Science & Technology, Kyungpook National University)
Woo, Sang-Uk (Department of Food Science & Technology, Kyungpook National University)
Yun, Chi-Young (Department of Biology, Daejeon University)
Kang, Seok-Woo (National Institute of Agicultural Science & Technology (NIAST))
Hwang, Jae-Sam (National Institute of Agicultural Science & Technology (NIAST))
Lee, Sang-Han (Department of Food Science & Technology, Kyungpook National University)
Publication Information
Food Science and Preservation / v.13, no.6, 2006 , pp. 796-802 More about this Journal
Abstract
In order to investigate the anti-inflammatory and cellular protective effects of Atractomorpha lata Motschulsky, Oxya japonica japonica Thunberg and Stethophyma magister Rehn, we first examined hydrogen peroxide-induced cytotoxicity in SH-SY5Y cells as well as antioxidant assays including DPPH and FRAP assays. We found that water, ethanol and methanol extracts of Oxya japonica japonica Thunberg and Stethophyma magister Rehn had potentials to anti-oxidant activity and especially water extract of Oxya japonica japonica Thunberg exhibited the most potent protective effects against $H-2O_2$-induced cytotoxicity in SH-SY5Y cells by MTT assay. Taken Together, these findings indicate that water extract of Oxya japonica japonica Thunberg could be useful insect resources for agrobiotechnological or oriental medicinal purposes.
Keywords
Atractomorpha lata Motschulsky; Oxya japonica japonica Thunberg; Stethophyma magister Rehn; anti-oxidant; DPPH; FRAP; MTT assay;
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1 Zhao, Y., Wang, X., Kawai, M., Liu, J., Liu, M. and Mori, A. (1995) Antioxidant activity of Chinese ant extract preparations. Acta. Med. Okayama, 49, 275-279
2 Joubert, E., Winterton, P., Britz, T.J. and Gelderblom, W.C. (2005) Antioxidant and pro-oxidant activities of aqueous extracts and crude polyphenolic fractions of rooibos (Aspalathus linearis). J. Agric. Food Chem., 53, 10260-10267   DOI   ScienceOn
3 Hsu, C.Y. (2006) Antioxidant activity of extract from Polygonum aviculare L. BioI. Res., 39, 281-288
4 Park, H. Y. (2000) Utilization of Microorganisms from Insects. Food Industry and Nutr., 6, 34-45
5 Ham, G.S. (2003) Utilization of chitosan as a regulatory molecule to increase health-beneficial substance and shelf-life of agricultural products. Food Industry Nutr., 8, 23-27
6 Hu, D., Liu, Q., Cui, H., Wang, H., Han, D. and Xu, H. (2005) Effects of amino acids from selenium-rich silkworm pupas on human hepatoma cells. Life Sci., 77, 2098-2110   DOI   ScienceOn
7 Li, S.P., Zhang, G.H., Zeng, Q., Huang, Z.G., Wang, Y.T., Dong, T.T. and Tsim, K.W. (2006) Hypoglycemic activity of polysaccharide, with antioxidation, isolated from cultured Cordyceps mycelia. Phytomed., 13, 428-433   DOI   ScienceOn
8 Xu, J.Z., Yeung, S.Y., Chang, Q., Huang, Y. and Chen. Z.Y. (2004) Comparison of antioxidant activity and bioavailability of tea epicatechins with their epimers. Br. J. Nutr., 91, 873-881   DOI   ScienceOn
9 Pulido, R., Bravo, L. and Saura-Calixto, F. (2000) Antioxidant activity of dietary polyphenols as determined by a modified ferric reducing/antioxidant power assay. J. Agric. Food. Chem., 48, 3396-3402   DOI   ScienceOn
10 Sroka, Z. and Cisowski, W. (2003) Hydrogen peroxide scavenging, antioxidant and anti-radical activity of some phenolic acids. Food Chem. Toxicol., 41, 753-758   DOI   ScienceOn
11 Choo, H.Y., Kim, H.H., Lee, D.W., Lee, S.M., Park, S.H., Choo, Y.M. and Kim, J.K. (2001) Practical Utilization of Entomopathogenic Nematodes, Steinernema carpocapsae Pocheon Strain and Heterorhabditis bacteriophora. Korean J. Appl. Entomol., 40, 69-76   과학기술학회마을
12 Han, S.M., Lee, S.H., Yun, C.Y., Kang, S.W., Lee, K.G., Kim, I.S., Yun, E.Y., Lee, P.J., Kim, S.Y. and Hwang, J.S. (2006) Inhibition of nitric oxide production by ladybug extracts(Harmonia axyridis) in LPS-activated BV-2 cells. Korean J. Appl. Entomol., 45, 31-36   과학기술학회마을
13 Hong, H. and Liu, G.Q. (2004) Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin, Life Sci., 74, 2959 - 2973   DOI   ScienceOn
14 Branen, A.S. (1975) Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene. J. Am. Oil Chem. Soc., 52, 59-63   DOI
15 Valko, M., Rhodes, C.J., Moncol, J., Izakovic, M. and Mazur, M. (2006) Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. BioI. Interact., 160, 1-40   DOI   ScienceOn
16 Lee, S.E., Ju, E.M. and Kim, J.H. (2001) Free radical scavenging and antioxidant enzyme fortifying activities of extracts from Smilax china root. Exp. Mol. Med., 33, 263-268   DOI   ScienceOn
17 Park, J.Y., Heo, J.C., Kwon, T.K., Chung, S.K., Kim, S.U. and Lee, S.H. (2005) Throughtput-compatible screening of anti-oxidative substances by insect extract library. Korean J. Food Preserv., 12, 482-488   과학기술학회마을
18 Blokhina, O., Virolainen, E. and Fagerstedt, K.V. (2003) Antioxidants, oxidative damage and oxygen deprivation stress: a review. Ann. Bot.-Lond., 91, 179-194   DOI   ScienceOn
19 Schlesier, K., Harwat, M., Bohm, V. and Bitsch, R. (2002) Assessment of antioxidant activity by using different in vitro methods. Free. Radic. Res., 36, 177-187   DOI
20 Paik, J.C. and Jung, S.H. (2004) Some Orthopteran Insects (Orthoptera: Insecta) of Jeju Island(1). Korean J. Soil Zool., 9, 44-52
21 Xu, Q., Konta, T., Nakayama, K., Furusu, A., Moreno-Manzano, V., Lucio-Cazana, J., Ishikawa, Y., Fine, LG., Yao, J. and Kitamura, M. (2004) Cellular defense against $H_2O_2$-induced apoptosis via MAP kinase-MKP-1 pathway. Free Radic. BioI. Med., 36, 985-993   DOI   ScienceOn
22 Ishikawa, Y. and Kitamura, M. (2000) Anti-apoptotic effect of quercetin: intervention in the JNK - and ERK-mediated apoptotic pathways. Kidney Int., 58, 1078-1087   DOI   ScienceOn
23 Chuang, S.M., Wang, I.C. and Yang, J.L. (2000) Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium. Carcinogenesis, 21, 1423-1432   DOI   ScienceOn
24 Spinella, F., Rosan, L., Di, Castro V., Nicotra, M.R., Natali, P.G. and Bagnato, A. (2004) Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothe1in a receptor in human ovarian carcinoma cells. Clin. Cancer. Res., 10, 4670-4679   DOI   ScienceOn
25 Lee, D.W., Choo, H.Y., Shin, O.K., Yun, J.S. and Kim, Y.S. (2002) Damage of Perennial ryegrass, Lolium perenne by chestnut brown chafer, Adoretus tenuimaculatus (Coleoptera: Scarabaeidae) and biological control with Korean isolate of entomopathogenic nematodes. Korean J. Appl. Entomol., 41, 217-223   과학기술학회마을
26 Murr, C., Schroecksnadel, K., Winkler, C., Ledochowski, M. and Fuchs, D. (2005) Antioxidants may increase the probability of developing allergic diseases and asthma. Med. Hypotheses, 64, 973-977   DOI   ScienceOn
27 Halliwell, B. and Gutterridge, J.M. (1990) Roles of free radicals and catalytic metal ions in human disease. An overview. In: Methods in Enzymology, Fleischer, S. and Packer, L. (Editors), Academic Press, New York, USA, 186, p.1-12
28 Valko, M., Izakovic, M., Mazur, M., Rhodes, C.J. and Telser, J. (2004) Role of oxygen radicals in DNA damage and cancer incidence. Mol. Cell. Biochem., 266, 37-56   DOI   ScienceOn
29 Wu, S.J., Tsai, J.Y., Chang, S.P., Lin, D.L., Wang, S.S., Huang, S.N. and Ng, L.T. (2006) Supercritical carbon dioxide extract exhibits enhanced antioxidant and anti-inflammatory activities of Physalis peruviana. J. Ethnopharmacol., doi: 10.1016/j.jep.2006.05.027
30 Kim, T.S., Lee, J.H., Choi, B.D. and Ryu, H.S. (1987) Nutritional value of dried paddy grasshopper, Oxya chineansis formosana, J. Korean Soc. Food Nutr., 16, 98-104   과학기술학회마을