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Anti-inflammatory and Cellular Protective Effects on Hydrogen Peroxide-induced Cytotoxicity of Grasshopper Extracts  

Park, Ja-Young (Department of Food Science & Technology, Kyungpook National University)
Heo, Jin-Chul (Department of Food Science & Technology, Kyungpook National University)
Woo, Sang-Uk (Department of Food Science & Technology, Kyungpook National University)
Yun, Chi-Young (Department of Biology, Daejeon University)
Kang, Seok-Woo (National Institute of Agicultural Science & Technology (NIAST))
Hwang, Jae-Sam (National Institute of Agicultural Science & Technology (NIAST))
Lee, Sang-Han (Department of Food Science & Technology, Kyungpook National University)
Publication Information
Food Science and Preservation / v.13, no.6, 2006 , pp. 796-802 More about this Journal
Abstract
In order to investigate the anti-inflammatory and cellular protective effects of Atractomorpha lata Motschulsky, Oxya japonica japonica Thunberg and Stethophyma magister Rehn, we first examined hydrogen peroxide-induced cytotoxicity in SH-SY5Y cells as well as antioxidant assays including DPPH and FRAP assays. We found that water, ethanol and methanol extracts of Oxya japonica japonica Thunberg and Stethophyma magister Rehn had potentials to anti-oxidant activity and especially water extract of Oxya japonica japonica Thunberg exhibited the most potent protective effects against $H-2O_2$-induced cytotoxicity in SH-SY5Y cells by MTT assay. Taken Together, these findings indicate that water extract of Oxya japonica japonica Thunberg could be useful insect resources for agrobiotechnological or oriental medicinal purposes.
Keywords
Atractomorpha lata Motschulsky; Oxya japonica japonica Thunberg; Stethophyma magister Rehn; anti-oxidant; DPPH; FRAP; MTT assay;
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