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http://dx.doi.org/10.3746/jkfn.2011.40.8.1107

Protective Effects of Food Including Hovenia dulcis on Acute Alcohol Intoxication  

Choi, Geun-Ho (Samsung Pharm. Co., Ltd.)
Kim, Jong-Gwan (Neopharm)
Kwon, Seoung-Taek (Neopharm)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.40, no.8, 2011 , pp. 1107-1112 More about this Journal
Abstract
Over-consumption of alcohol leads to many side-effects such as malnutrition, liver disease, and neuronal disorders and many investigators have tired to identify methods for preventing the side-effects of drinking. In this study, we demonstrated the protective effect of a new food component, SAC-1, containing Hovenia dulcis Thumb and Lonicera caerulea Thumb extract against the side-effects of drinking. We observed that blood alcohol concentration, glutamic oxaloacetate transaminase, lipid peroxidation, and total glutathione level decreased significantly in plasma and liver of mice fed the SAC-1 extract before alcohol intoxication. In particular, SAC-1 had more of a protective effect than that of Hovenia dulcis Thumb extract alone. These results suggest that SAC-1 should further be developed to treat alcohol detoxification and stimulate antioxidative potentials.
Keywords
alcohol intoxication; Hovenia dulcis; functional food; liver; alcohol toxicity;
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Times Cited By KSCI : 5  (Citation Analysis)
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