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http://dx.doi.org/10.3746/jkfn.2011.40.3.357

Biological Activity of Browning Compounds from Processed Garlics Separated by Dialysis Membrane  

Shin, Jung-Hye (Namhae Garlic Research Institute)
Kang, Min-Jung (Namhae Garlic Research Institute)
Kim, Ra-Jeong (Dept. of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
Ryu, Ji-Hyun (Dept. of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
Kim, Mi-Ju (Dept. of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
Lee, Soo-Jung (Dept. of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
Sung, Nak-Ju (Namhae Garlic Research Institute)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.40, no.3, 2011 , pp. 357-365 More about this Journal
Abstract
This study was conducted to compare biological activity of browning compounds from fresh, red and black garlic. Water soluble browning compounds were separated from fresh, red and black garlic by dialysis membrane. Antioxidation and other biological activities of freeze dried inner and outer parts from garlics were compared. pH of fresh and red garlic dialysis solutions were higher in inner part of membrane, but black garlic dialysis solution showed reverse tendency. Browning intensities of all tested samples were higher in outer part of dialysis solutions. In inner part dialysis solutions, contents of total phenol compounds were the lowest in red garlic while their contents were the highest in black garlic and thereafter, were the highest in inner part of dialysis solution made from red garlic. Flavonoids content was the highest in inner part of red garlic dialysis solution. Total pyruvate content was higher in outer part of fresh and red garlic dialysis solution which showed the opposite results in black garlic. Total thiosulfate content was the highest in black garlic, red garlic and fresh garlic in order. Antioxidant activities have some similarities among garlic products. DPPH radical scavenging activity was higher in inner part of fresh and black garlic and outer part of red garlic. Tyrosinase inhibition activity was higher in browning compounds of red garlic than fresh and black garlic. $\alpha$-glucosidase inhibition activity of tested samples were higher in inner part of dialysis solution than outer part, and showed higher activity in red garlic than fresh garlic at low sample concentrations.
Keywords
red garlic; black garlic; browning compounds; dialysis; antioxidant activity;
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1 Lee YR, Hwang IG, Woo KS, Kim DJ, Hong JT, Jeong HS.2007. Antioxidative activities of the ethyl acetate fraction from heated onion (Allium cepa). Food Sci Biotechnol 16: 1041-1045.   과학기술학회마을
2 Somoza V. 2005. Five years of research on health risks and benefits of Maillard reaction products: An update. Mol Nutr Food Res 49: 663-672.   DOI
3 Moreno FJ, Corzo-Martinez M, Dolores del Castillo M,Villamiel M. 2006. Changes in antioxidant activity of dehydrated onion and garlic during storage. Food Res Int 39: 891-897.   DOI
4 Jung SW, Lee NK, Kim SJ, Han DS. 1995. Screening of tyrosinase inhibitor from plants. Korean J Food SciTechnol 27: 891-896.   과학기술학회마을
5 Jung EY, Hong YH, Kim SH, Suh HJ. 2010. Physiological effects of formulations added with black garlic extract on skin care: oxidative stress, tyrosinase and elastase activities.J Korean Soc Food Sci Nutr 39: 662-668.   과학기술학회마을   DOI
6 Cha JY, Yang HJ, Jeong JJ, Seo WS, Park JS, Ok M, ChoYS. 2010. Tyrosinase inhibition activity and antioxidant capacity by fermented products of some medicinal plants. JLife Sci 20: 940-947.   과학기술학회마을   DOI
7 Shin JH, Kang MJ, Lee SJ, Yang SM, Ryu JH. Sung NJ.2009. Biological activity of dried garlic, red ginseng and tieirmixture. J Korean Soc Food Sci Nutr 38: 1633-1639.   DOI
8 Mooradian AD, Thurman JE. 1999. Drug therapy of post prandial hyperglycemia. Drugs 57: 19-29.
9 Baynes JW, Thorpe SR. 1999. Role of oxidative stress in diabetes complications: a new perspective on an old paradigm.Diabetes 48: 1-9.   DOI
10 Lee JW, Lee SK, Do JH, Sung HS, Shim KH. 1995. Browning reaction of fresh ginseng (Panax ginseng C. A. Meyer) as affected by heating temperature. Korean J Ginseng Sci 19:249-253.   과학기술학회마을
11 Shin JH, Choi DJ, Chung MJ, Kang MJ, Sung NJ. 2008.Changes of physicochemical components and antioxidant activity of aged garlic at different temperatures. J KoreanSoc Food Sci Nutr 37: 1174-1181.   과학기술학회마을   DOI
12 Delgado-Andrade C, Rufian-Henares JA, Morales FJ. 2005.Assessing the antioxidant activity of melanoidins from coffee brews by different antioxidant methods. J Agric Food Chem 53: 7832-7836.   DOI
13 Queiroz YS, Ishimoto EY, Bastos DHM, Sampaio GR, Torres EAFS. 2009. Garlic (Allium sativum) and ready-to-eat garlic products: In vitro antioxidant activity. Food Chem115: 371-374.   DOI
14 Lee SJ, Shin JH, Kang MJ, Jung WJ, Ryu JH, Kim RJ, SungNJ. 2010. Antioxidant activity of aged red garlic. J Life Sci20: 775-781.   DOI
15 Lertittikul W, Benjakul S, Tanaka M. 2007. Characteristics and antioxidative activity of Maillard reaction products from porcine plasma protein-glucose model system as influenced by pH. Food Chem 100: 669-677.   DOI
16 Woo KS, Yoon HS, Lee YR, Lee JS, Kim DJ, Hong JT,Jeong HS. 2007. Characteristics and antioxidative activity of volatile compounds in heated garlic (Allium sativum).Food Sci Biotechnol 16: 822-827.   과학기술학회마을
17 Kim SD, Do JH, Oh HI. 1981. Antioxidant activity of Panax ginseng browning products. J Korean Agric Chem Soc 24:161-166.   과학기술학회마을
18 Jang EK, Seo JH, Lee SP. 2008. Physiological activity and antioxidative effects of aged black garlic (Allium sativum)extract. Korean J Food Technol 40: 443-448.   과학기술학회마을
19 Schwimmer S, Weston WJ. 1961. Onion flavor and order, enzymatic development of pyruvic acid in onion as a measure of pungency. J Anal Food Chem 9: 301-304.   DOI
20 Freeman GG, Mcbreen F. 1973. A rapid spectrophotometric methods of determination of thiosulfinate in onion and its significance in flavor studies. Biochem Soc Trans 1: 1150-1154.   DOI
21 Blois MS. 1958. Antioxidant determination by the use of a stable free radical. Nature 181: 1199-1200.   DOI
22 Oyaizu M. 1986. Studies on products of browning reactions: antioxidative activities of products of browning reaction prepared from glucosamine. Jpn J Nutr 44: 307-315.   DOI
23 Re R, Pellegrini N, Pannala A, Yang M, Rice-Evans C. 1999.Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26:1231-1237.   DOI
24 Shin JH, Choi DJ, Lee SJ, Cha JY, Kim JG, Sung NJ. 2008.Changes of physicochemical components and antioxidant activity of garlic during its processing. J Life Sci 18: 1123-1131.   과학기술학회마을   DOI
25 Song HS, Moon KY. 2006. In vitro antioxidant activity profiles of $\beta$-glucans isolated from yeast Sacharomyces cerevisiae and mutant Sacchromyces cerevisiae IS2. Food Sci Biotechnol 15: 437-440.
26 Yagi A, Kanbara T, Morinobu N. 1986. The effect of tyrosinase inhibition for aloe. Planta Med 3981: 517-519.
27 Choe M, Kim DJ, Lee HJ, You JK, Seo DJ, Lee JH, ChungMJ. 2008. A study on the glucose regulating enzymes and antioxidant activities of water extracts from medicinal herbs. J Korean Soc Food Sci Nutr 37: 542-547.   과학기술학회마을   DOI
28 Moriguchi T, Saito H, Nishiyama N. 1997. Anti-aging effect of aged garlic extract in the inbred brain atrophy mouse model. Clin Exp Phaemacol Physiol 24: 235-242.   DOI
29 Son SJ, Lee SP. 2010. Effects of black garlic on the rheological and functional propertied of garlic fermented by Leuconostoc mesenteroides. J Korean Soc Food Sci Nutr39: 864-871.
30 Shin JH, Choi DJ, Lee SJ, Che JY, Sung NJ. 2008. Antioxidant activity of black garlic (Allium sativum L). J Korean SocFood Sci Nutr 37: 965-971.   과학기술학회마을   DOI
31 Kang MJ, Lee SJ, Shin JH, Kang SK, Kim JG, Sung NJ.2008. Effect of garlic with different processing on lipid metabolismin 1% cholesterol fed rats. J Korean Soc Food Sci Nutr 37: 162-169.   과학기술학회마을   DOI
32 Gutfinger T. 1981. Polyphenols in olive oils. JAOCS 58:966-968.   DOI
33 Amagase H, Petesch BL, Matsuura H, Kasuga S, Itakura Y. 2001. Intake of garlic and its bioactivity components. JN131: 955S-962S.
34 Ide N, Lau B HS, Ryu K, Matsuura H, Itakura Y. 1999.Antioxidant effects of fructosyl arginine, a Maillard reaction product in aged garlic extract. J Nutr Biochem 10:372-376.   DOI
35 Liu L, Yeh YY. 2001. Water-soluble organosulfur compounds of garlic inhibit fatty acid and triglyceride synthesis in cultured rat hepatocytes. Lipids 36: 395-400.   DOI
36 Moreno MIN, Isla MI, Sampietro AR, Vattuone MA. 2000.Comparison of the free radical scavenging activity of propolis from several region of Argentina. J Ethnopharmacol71: 109-114.   DOI
37 Cavagnaro PF, Senalik D, Galmarini CR, Simon PW. 2005.Correlation of pungency, thiosulfinates, antiplatelet activity and total soluble solids in two garlic families. American Society for Horticultural Sciences Annual Conference, Las Vegas, NV, USA. p 1019.
38 Heber D. 1997. The stinking rose: organosulfur compounds and cancer. J Clin Nutr 66: 425-426.   DOI
39 Borek C. 2001. Antioxidant health effects of aged garlic extract. J Nutr 131: 1010S-1015S.   DOI