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http://dx.doi.org/10.3746/jkfn.2011.40.2.163

Nutritional Properties and Biological Activities of Artemisia annua L.  

Ryu, Ji-Hyun (Dept. of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
Kim, Ra-Jeong (Dept. of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
Lee, Soo-Jung (Dept. of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
Kim, In-Soo (Dept. of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
Lee, Hyun-Ju (Division of Food Science, International University of Korea)
Sung, Nak-Ju (Dept. of Food Science and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.40, no.2, 2011 , pp. 163-170 More about this Journal
Abstract
The nutritional properties and biological activities of leaves and stems of Gaeddongssuk (Artemisia annua L.) were investigated. Contents of moisture, crude lipid and crude protein were significantly higher in the leaves, and then ash, crude fiber and mineral were significantly higher in the stems. Contents of total phenols and flavonoids of leaves were about 2 fold higher than those of stems. Antioxidant activity was significantly increased in a dose-dependent manner; also, water and ethanol extracts of leaves were stronger than those of stems. Especially, DPPH radical scavenging activity, reducing power and tyrosinase inhibition activity were significantly higher in leaves extracts than stems extracts of Gaeddongssuk. But, ${\alpha}$-glucosidase inhibition activity was higher in stem than its leaves extract. In MTT assay by human breast adenocarcinoma cell line MCF-7 and MDA-MB-231, ethanol extracts of leaves showed the highest anticancer activity; the rates of growth inhibition were 76.26% and 52.59% on MCF-7 and MDA-MB-231 cells, at the concentration of $250\;{\mu}g$/mL, respectively. In conclusion, biological activities of extracts from Gaeddongssuk were dependent on the fiber, phenolic and flavonoid content.
Keywords
Gaeddongssuk (Artemisia annua L.); antioxidant activity; tyrosinase; ${\alpha}$-glucosidase; MTT assay;
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