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http://dx.doi.org/10.3746/jkfn.2010.39.4.481

Antioxidant and Nitrite Scavening Activity and α-Glucosidase Inhibitory Effect of Water Extract from Schizandra chinensis Baillon  

Cho, Hea-Eun (Dept. of Food and Nutrition, Silla University)
Choi, Young-Ju (Dept. of Food and Nutrition, Silla University)
Cho, Eun-Kyung (Dept. of Bio-Food Materials, Silla University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.39, no.4, 2010 , pp. 481-486 More about this Journal
Abstract
The nutraceutical role of omija (Schizandra chinensis Baillon) water extract (OWE) was determined through the analysis of antioxidant activity, nitrite scavening activity, and xanthine oxdiase and $\alpha$-glucosidase inhibitory effects. Antioxidant activity of OWE was measured by using 2,2-diphenyl-1-picryl-hydrazyl (DPPH) free radical scavenging activity and superoxide dismutase-like activity (SODA). DPPH radical scavenging activity and SODA increased in a dose-dependent manner, and was about 49.0% at 2.5 mg/mL and 69.2% at 5 mg/mL, respectively. The xanthine oxidase and $\alpha$-glucosidase inhibitory activities of OWE were about 88.8% and 86.2% at 1 mg/mL, respectively. Nitrite scavenging activity of OWE was about 54.9%, 42.4%, and 34.2% on pH 1.2, 3.0, and 6.0 at 1 mg/mL, respectively. These results suggest that OWE has a strong antioxidant activity, and xanthine oxidase and $\alpha$-glucosidase inhibitory effects.
Keywords
antioxidant activity; xanthine oxidase; $\alpha$-glucosidase; Schizandra chinensis Baillon; nitrite scavenging activity;
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